scholarly journals Prevalence and factors associated with chronic kidney disease among hospitalized patients in a university hospital in the city of São Paulo, SP, Brazil

2015 ◽  
Vol 37 (1) ◽  
Author(s):  
Natalia Alencar de Pinho ◽  
Giovänio Vieira da Silva ◽  
Angela Maria Geraldo Pierin
2021 ◽  
Vol 55 ◽  
pp. 76
Author(s):  
Thais Claudia Roma de Oliveira Konstantyner ◽  
Camila Bertini Martins ◽  
Carla Gianna Luppi ◽  
Suely Miyuki Yashiro ◽  
Nívia Aparecida Pissaia Sanches ◽  
...  

This study aimed to verify socio-demographic and baseline clinical factors associated with death in a hospital cohort of patients with COVID-19. A retrospective cohort study was conducted between February and December 2020 in a university hospital in the city of São Paulo, using Hospital Epidemiology Center data. RT-PCR-positive patients were selected to compose the sample (n = 1,034). At the end of the study, 362 (32%) patients died. In this cohort, age equal to or greater than sixty years (HR = 1.49) and liver disease (HR = 1.81) were independent risk factors for death from COVID-19 associated with higher in-hospital mortality.


Author(s):  
Gabriela Togni ◽  
Paulo José Puccinelli ◽  
Taline Costa ◽  
Aldo Seffrin ◽  
Claudio Andre Barbosa de Lira ◽  
...  

Background: The COVID-19 pandemic negatively affected physical activity levels. This study investigated the factors associated with the change in physical activity level in Brazilians residing in the city of São Paulo. Methods: A self-administered questionnaire, addressing personal data, restriction level, education level, family income, daily working hours, and physical activity level, was answered by 2140 volunteers, of which 1179 were excluded because the answers were either incomplete or the respondents were not from São Paulo. The total number of participants selected was 961 (581 female and 380 male). Results: The physical activity level adopted prior to the pandemic period (p < 0.001) and family income (p = 0.001) correlated significantly with physical activity level reduction during the pandemic. The proportion of people who reduced their physical activity was greater among those who were very active than those who were active (adjusted prevalence ratio [aPR]: 0.65 [confidence interval (CI): 0.52–0.80]) or insufficiently active [aPR: 0.39 (0.18–0.82)]. The proportion of people who reduced their physical activity was greater among those who received a salary less than minimum wage (MW) than those who received a salary between three to six times minimum wage [(aPR: 0.50 (CI 0.35–0.70)] or more than 6 MW [(aPR: 0.56 (CI 0.40–0.79)]. Conclusions: A higher prevalence of Brazilians residing in the city of São Paulo reduced their physical activity who had a vigorous level of physical activity prior to the pandemic and who received less than a MW.


2017 ◽  
Vol 135 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Maria Alice Muniz Domingos ◽  
Alessandra Carvalho Goulart ◽  
Paulo Andrade Lotufo ◽  
Isabela Judith Martins Benseñor ◽  
Silvia Maria de Oliveira Titan

ABSTRACT CONTEXT AND OBJECTIVE: Chronic kidney disease (CKD) has become an important public health issue. The socioeconomic burden of renal replacement therapy (RRT) is very high, as is CKD-related cardiovascular mortality and morbidity. Preventive and therapeutic measures only have modest impact and more research is needed. Few cohort studies have been conducted on populations with CKD. Our aim was to establish a cohort that would include more advanced forms of CKD (stages 3 and 4). Data collection was focused on renal and cardiovascular parameters. DESIGN AND SETTING: Prospective cohort study; São Paulo, Brazil. METHODS: Recruitment took place in Hospital das Clínicas, São Paulo, from March 2012 to December 2013. Data relating to medical history, food-frequency questionnaire, anthropometry, laboratory work-up, calcium score, echocardiography, carotid intimal-medial thickness, pulse-wave velocity, retinography and heart rate variability were collected. A biobank including serum, plasma, post-oral glucose tolerance test serum and plasma, urine (morning and 24-hour urine) and DNA was established. RESULTS: 454 participants (60% men and 50% diabetics) of mean age 68 years were enrolled. Their mean estimated glomerular filtration rate-CKD Epidemiology Collaboration was 38 ml/min/1.73 m2. Follow-up is ongoing and the main outcomes are the start of RRT, cardiovascular events and death. CONCLUSIONS: The PROGREDIR cohort is a promising prospective study that will allow better understanding of CKD determinants and validation of candidate biomarkers for the risks of CKD progression and mortality.


2021 ◽  
Author(s):  
Luiz Vinicius Leao Moreira ◽  
Gabriela Barbosa ◽  
Luciano Kleber de Souza Luna ◽  
Alberto Fernando Oliveira Justo ◽  
Ana Paula Cunha Chaves ◽  
...  

Objective: To assess the COVID-19 frequency rates in hospitalized patients (HP) and healthcare workers (HCW), viral load inference, and the impact of vaccination and variants of concern (VOC) during the first pandemic wave. Methods: We evaluated the COVID-19 diagnostics at Hospital Sao Paulo, Brazil, from March 2020 to April 2021, in 10,202 samples (6,502 HP and 3,700 HCW) tested by RT-qPCR, inferring viral load by cycle threshold (Ct) values, and frequency rates. Results: SARS-CoV-2 was detected in 31.27% of individuals (32.23% HP and 29.80% HCW). The mean age of HP positives was 57.26 +/- 18.29 years (median = 59), with a mean Ct value of 25.55 +/- 6.07. Neither age nor Ct values in both groups have significantly differed during the first and second waves or even since the predominance of VOC P.1 on March 2021. Conclusions: The COVID-19 epidemic curves of HP and HCW accompanied the variations reported in Sao Paulo city, as well as the variation of hospitalization and occupancy of ICU beds. The VOC P.1 has no impact on the viral load, since its predominance in March 2021. The vaccination of HCW may have contributed to a decrease in the positivity rates, although more studies will provide a better understanding of the impact of immunization on the COVID-19 pandemic.


2008 ◽  
Vol 2 (1) ◽  
pp. 93-94 ◽  
Author(s):  
M. C. Magri ◽  
M. E. F. Canziani ◽  
S. A. Draibe ◽  
E. Santos-Fortuna ◽  
A. C. de-Araujo

2014 ◽  
Vol 50 (1) ◽  
pp. 95-102 ◽  
Author(s):  
Mariana G.R. Santos ◽  
Angela T. Paes ◽  
Adriana Sanudo ◽  
Zila M. Sanchez

2019 ◽  
Vol 8 (6) ◽  
Author(s):  
Alana Karoline Penha do Nascimento ◽  
Brenda Lavínia Calixto dos Santos ◽  
Abrahão Alves de Oliveira Filho ◽  
Heloisa Mara Batista Fernandes de Oliveira

Com o aumento da expectativa de vida dos brasileiros, houve também o crescimento da incidência de doenças crônicas degenerativas, como as alterações renais, que estão afetando cada vez mais a população como um todo, envolvendo o risco de desenvolver a insuficiência renal crônica e/ou aguda. Com isso é necessário à realização de exames laboratoriais rotineiros, a fim de se diagnosticar precocemente tais distúrbios, sendo necessária a solicitação dos marcadores laboratoriais. O propósito deste trabalho foi descrever o padrão de exames solicitados para a avaliação do perfil renal de pacientes atendidos no Hospital Universitário Ana Bezerra. A metodologia adotada trata-se de um estudo epidemiológico delineado como retrospectivo documental, em que foi analisado o quantitativo dos exames solicitados para a avaliação do perfil renal no banco de dados do Laboratório de Análises Clínicas do Hospital Universitário Ana Bezerra do período de junho de 2017 a junho de 2018. Diante da pesquisa realizada foi possível evidenciar que foram solicitados 31.159 exames para avaliar o perfil renal, sendo a creatinina o exame mais solicitado para os pacientes atendidos no Hospital Universitário Ana Bezerra.Descritores: Rim; Testes de Função Renal; Creatinina.ReferênciasBrasil. Ministério da Saúde. Indicadores e Dados Básicos: Brasil - 2009 IDB-2009 Brasília: Ministério da Saúde. Disponível em: http://tabnet.datasus.gov/. Acesso em 11 Agosto 2018.Begman R. Avaliação de pacientes com doença renal crônica em tratamento especializado por equipe multidisciplinar. J Bras Nefrol. 2006;28(3 Supl 2):33-5.Godinho TM, Lyra TG, Braga OS, Queiroz RA, Alves JA, Kraychete AC et al. Perfil do paciente que inicia hemodiálise de manutenção em Hospital Público de Salvador, Bahia. J Bras Nefrol. 2006;28(2):96-103.Zawada ET. Inicio da diálise. In: Daugiardas JT, Blake PG, Ing T. Manual de Diálise. 3. ed. Rio de Janeiro: Guanabara Koogan; 2003. p.4-11.Kohagura K, Tomiyama N, Kinjo K, Takishita S, Iseki K. Prevalence of anemia according to stage of chronic kidney disease in a large screening cohort of Japanese. Clin Exp Nephrol. 2009;13(6):614-20.Guyton AC, Hall JE, Guyton AC. Tratado de fisiologia médica. Elsevier Brasil; 2006.Azevedo AC, Gómez JFB, Lugon JR, Graciano ML. Detecção de disfunção renal através da dosagem de creatinina em amostra de gota de sangue seca no papel filtro. J Bras Nefrol. 2016;38(1):15-21.Silva Junior, Matos SMA. Padrões alimentares e doença renal crônica. In: Cruz J, Cruz HMM, Kirsztajn GM, Oliveira RB, Barros RT (eds). Atualidades em Nefrologia. 14.ed. São Paulo: Sarvier; 2016.Tizatto LAP, Machado RAF. Exames diagnósticos e tratamento de urolitíase: uma revisão da literatura. Thêma et Scientia. 2016;6(1):212-29.Telles C, Boita ERF. Importância da terapia nutricional com ênfase no cálcio, fósforo e potássio no tratamento da doença renal crônica. Perspectiva Erechim. 2015;39(145):143-54.Bottini PV, Afaz SH, Silveira S, Garlipp CR. Utilização da relação albumina/creatinina no diagnóstico de microalbuminúria. J Bras Patol  Med Lab. 2005;41(2):99-103.


2008 ◽  
Vol 126 (1) ◽  
pp. 34-40
Author(s):  
Marcelo Montebello Lemos ◽  
Alessandra Coelho Pedrosa ◽  
Alze Pereira Tavares ◽  
Miguel Ângelo Góes ◽  
Sérgio Antônio Draibe ◽  
...  

CONTEXT AND OBJECTIVE: The choice of an antihypertensive drug is based on several criteria and specific situations give rise to doubt and controversy. The aim here was to evaluate physicians’ approaches towards treatment with antihypertensive agents in specific situations. DESIGN AND SETTING: Cross-sectional study, at Universidade Federal de São Paulo, São Paulo. METHODS: A questionnaire was applied during a nephrology meeting to evaluate individual approaches towards each hypothetical clinical situation. The questionnaire consisted of five multiple-choice questions (clinical cases) concerning controversial aspects of antihypertensive therapy. RESULTS: A total of 165 questionnaires were analyzed. Most participants were nephrologists (93.2%). There was a preference for angiotensin-converting enzyme (ACE) inhibitors in at least two of the cases. Only 57.2% of the physicians were correct in choosing beta-blockers as the first-line drugs for patients with ischemic coronary disease. Moreover, 66.2% chose ACE inhibitors as the first-line drugs for patients with chronic kidney disease and proteinuria. About 5% of the physicians did not follow the current recommendations for the use of ACE inhibitors in diabetic patients with microalbuminuria. The most controversial question concerned the first-line drug for advanced chronic kidney disease. Most physicians were correct in choosing calcium channel blockers and avoiding ACE inhibitors in renovascular hypertension in the case of a patient with a single functioning kidney. CONCLUSIONS: Most physicians adopted the correct approach, but some had an alternative strategy for the same situations that was not based on evidence.


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