An Application of Newton’s Law Of Cooling

1974 ◽  
Vol 67 (2) ◽  
pp. 141-142
Author(s):  
James F. Hurley

Many introductory calculus texts now include a section devoted to applications of the exponential function. The large variety of commonly encountered phenomena whose processes of growth or decay are exponential affords a rich source of interesting and appealing applications. Students who can easily compute the size a century hence of a world population growing continuously at a rate of 2 percent need little further in the way of convincing that calculus can be useful in the real world of today. Problems involving radioactive decay and growth of investments also strike most students as interesting, dealing as they do with questions that, if not familiar, have at least been heard of by most students.

AKSEN ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 19-31
Author(s):  
Andrey Caesar Effendi ◽  
LMF Purwanto

The use of digital technology today can be said to be inseparable in our daily lives. Digital technology isslowly changing the way we communicate with others and the environment. Socialization that is usuallyface-to-face in the real world now can be done to not having to meet face-to-face in cyberspace. Thisliterature review aims to see a change in the way of obtaining data that is growing, with the use of digitaltechnology in ethnographic methods. The method used in this paper is to use descriptive qualitativeresearch methods by analyzing the existing literature. So it can be concluded that the use of digitalethnography in the architectural programming process can be a new way of searching for data at thearchitectural programming stage.


spontaneously invented a name for the creature derived from the most prominent features of its anatomy: kamdopardalis [the normal Greek word for ‘giraffe*]. (10.27.1-4) It is worth spending a little time analysing what is going on in this passage. The first point to note is that an essential piece of information, the creature’s name, is not divulged until the last possible moment, after the description is completed. The information contained in the description itself is not imparted directly by the narrator to the reader. Instead it is chan­ nelled through the perceptions of the onlooking crowd. They have never seen a giraffe before, and the withholding of its name from the reader re-enacts their inability to put a word to what they see. From their point of view the creature is novel and alien: this is conveyed partly by the naive wonderment of the description, and partly by their attempts to control the new phenomenon by fitting it into familiar categories. Hence the comparisons with leopards, camels, lions, swans, ostriches, eyeliner and ships. Eventually they assert conceptual mastery over visual experience by coining a new word to name the animal, derived from the naively observed fea­ tures of its anatomy. However, their neologism is given in Greek (kamdopardalis), although elsewhere Heliodoros is scrupulously naturalistic in observing that Ethiopians speak Ethiopian. The reader is thus made to watch the giraffe from, as it were, inside the skull of a member of the Ethiopian crowd. The narration does not objectively describe what they saw but subjectively re­ enacts their ignorance, their perceptions and processes of thought. This mode of presentation, involving the suppression of an omniscient narrator in direct communication with the reader, has the effect that the reader is made to engage with the material with the same immediacy as the fictional audience within the frame of the story: it becomes, in imagination, as real for him as it is for them. But there is a double game going on, since the reader, as a real person in the real world, differs from the fictional audience inside the novel precisely in that he does know what a giraffe is. This assumption is implicit in the way the description is structured. If Heliodoros* primary aim had been to describe a giraffe for the benefit of an ignorant reader, he would surely have begun with the animal’s name, not withheld it. So for the reader the encounter


2017 ◽  
Vol 69 (11) ◽  
pp. 109 ◽  
Author(s):  
Tabassome Simon ◽  
Etienne Puymirat ◽  
Francois Schiele ◽  
Pierre Coste ◽  
Denis Angoulvant ◽  
...  

Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 2335-2335
Author(s):  
Shammim Haji ◽  
Jignesh P Patel ◽  
Vivian Auyeung ◽  
Lara N Roberts ◽  
Julia Czuprynska ◽  
...  

Abstract Do the safety and efficacy outcomes reported in the clinical trials of direct oral anticoagulants (DOAC) translate to the 'real-world'? Background: A number of DOACs are now available for clinicians to prescribe in clinical practice. Whilst the results from large clinical trials demonstrate that these agents are as effective as vitamin K antagonists, there is some concern that the patients studied in the trials were not representative of patients, clinicians encounter in everyday practice. The aim of our study was to compare the real-world clinic population commenced on a DOAC to that from the clinical trials for these agents, in order to assess potential differences in safety and efficacy. Patients and methods: A retrospective observational cohort study was undertaken. Patients who were initiated on a DOAC (apixaban, dabigatran and rivaroxaban) at a large teaching hospital in South East London between 1st August 2012 and 31st July 2014 were identified through pharmacy issue data with those followed-up for a minimum of 6 months included. Baseline demographic data, rates of stroke/VTE and rates of major/non-major clinically relevant (NMCR) (ISTH definition) bleeding were assessed and compared to pooled data reported from the corresponding Phase III trials. Differences between groups were compared using t-tests or chi-squared tests. Results: During the review period, 748 patients were initiated on a DOAC, 365 for atrial fibrillation (AF) and 383 for venous thromboembolism (VTE). In terms of demographic differences, the real-world AF population comprised more females, were significantly older, had poorer renal function and a lower body weight. In contrast, the real-world VTE population typically had a higher body weight and poorer renal function, compared to the trial population, (table 1). Efficacy of DOACs was found to be similar across both the VTE and AF populations. With respect to safety, the real-world AF population experienced similar rates of major bleeding and a significantly lower rate of NMCR bleeding compared to the trial populations. In contrast, the real-world VTE population experienced a significantly higher rate of major bleeding, particularly gastrointestinal bleeding. Although the rate of NMCR bleeding was similar, there was a significantly higher rate of urogenital bleeding in the real-world VTE population, specifically heavy menstrual bleeding in women. Conclusions: The efficacy outcomes of DOAC use in a real-world AF and VTE population are consistent with the Phase III trials, despite some significant differences in baseline characteristics. However, a significantly increased rate of major bleeding was observed in the real-world VTE population, which requires further investigation. Table 1. Baseline demographic characteristics, efficacy and safety outcomes in the real-world population versus the trial population Atrial Fibrillation Venous Thromboembolism Trial population+N=28,342 Real-world population Trial population++ Real-world population N=365 N=8,716 N=383 Baseline Demographics, mean (SD) unless otherwise specified Age, years 72 (9.6) 76.8 * (12.1) 56.9 (14.2) 55.6 (18.7) Female (%) 10451 (36.9) 215 * (58.9) 3753 (43.1) 184 (48.0) Weight, kg 82.7 (19.5) 77.3 * (22.6) 84.9 (19.6) 88.2 * (23.0) Creatinine clearance, mL/min 69 (26.7) 58.1 * (26.9) 105.8 (40.7) 91.1 * (37.6) Concomitant aspirin therapy 10341 (36.5) 49 * (13.4) - 0 (0) Previous VKA use (%) 15711 (55.4) 193 (52.9) - 85 (22.2) Efficacy (%) All-cause mortality 1695 (6.0) 37 * (9.1) 160 (1.8) 10 (2.5) Stroke 676 (2.4) 8 (2.0) - 1 (0.3) VTE 39 (0.1) 1 (0.2) 192 (2.2) 7 (1.8) Safety (%) Major Bleeding 1419 (5.0) 17 (4.2) 79 (0.9) 15 * (3.8) Intracranial 170 (0.6) 1 (0.2) 6 (0.1) 2 * (0.5) Gastrointestinal 644 (2.3) 8 (2.0) 8 (0.1) 8 * (2.0) Non-major Clinically relevant (NMCR) bleeding 4824 (17.0) 30 * (7.4) 540 (6.2) 26 (6.6) Gastrointestinal - 9 (2.2) 53 (4.2) 10 (2.5) Urogenital 296 (4.2) 16 (3.9) 100 (2.5) 38 * (9.6) +Pooled data from ARISTOTLE, RE-LY and ROCKET-AF trials ++Pooled data from AMPLIFY, RE-COVER and EINSTEIN-PE/DVT trials *p<0.05 Disclosures Patel: Bayer plc: Research Funding. Auyeung:Bayer PLC: Research Funding. Arya:Bayer plc: Research Funding.


2019 ◽  
Vol 22 (1-2) ◽  
pp. 6
Author(s):  
Manicardi, V.

OBJECTIVE OF THE STUDY To evaluate the generalizability of the results of recent CVOTs on SGLT2i (EMPA-REG OUTCOMES, CANVAS, DECLARE-TIMI 58 and VERTIS-CV) in patients with T2DM in the real world. DESIGN AND METHODS Database of AMD Annals 2018 was used in this study, including all patients cared for by 222 diabetes centers during 2016. Starting from the eligibility criteria adopted in the different trials, the analysis aimed to identify the subjects potentially eligible for each trial, compare their characteristics with those of the population recruited in the trials, and evaluate the current use of these drugs among the potentially eligible patients registered in AMD Annals database. RESULTS The evaluable cases (i.e. presence of information on all eligibility criteria) ranged from 149.064 for the CANVAS to the 342.205 subjects for the EMPAREG-OUTCOME. Overall, the eligible patients in AMD Annals ranged from 40,039 for the EMPAREG OUTCOME study (11.7%) to 144,166 (55.9%) for DECLARE-TIMI 58. The percentage of patients actually treated ranged from 4.4% (6.373) for DECLARE-TIMI 58 to 6.6% (2.917) for CANVAS. As compared to RCTs’ populations, AMD Annals population was older, included a larger proportion of women, showed slightly lower BMI and better metabolic control, and longer diabetes duration. Prevalence of major cardio-cerebrovascular events was lower, while the percentage of subjects with peripheral vasculopathy was higher; the proportion of subjects with reduced glomerular filtrate or albuminuria and diabetic retinopathy was higher. CONCLUSIONS The generalizability of CVOTs’ results to the real world patients is only partial, because the populations are quite different. A very low clinical use of SGLT-2i is documented. This is at least in part due to the strict AIFA criteria for reimbursement, which reduce the proportion of patients who could benefit from treatment with SGLT2i on major cardiovascular events and mortality; however, an identical advantage of the treatment obtained in RCTs cannot be hypothesized in the AMD Annals population. KEY WORDS type 2 diabetes; CVOT; real world; generalizability; SGLT2i


2014 ◽  
Vol 11 (4) ◽  
pp. 157-162 ◽  
Author(s):  
H. Wayne Cecil

This article shares the motivation, process, and outcomes of using humorous scenes from television comedies to teach the real world of tax practice. The article advances the literature by reviewing the use of video clips in a previously unexplored discipline, discussing the process of identifying and selecting appropriate clips, and introducing and reviewing fair use guidelines for copyrighted video materials in the classroom.


2020 ◽  
pp. 3-14
Keyword(s):  
The Real ◽  

By the term “library awareness,” I refer to the way in which the library is understood in a given text and, extrapolating from the text, in a given period or place.1 It can also signify the various answers to a question about the meaning of a library: in other words, the awareness of the principal and practical meanings of libraries, the perception of them as an aggregate, and the understanding that an aggregate of books is equivalent to an aggregate of knowledge and is even connected to other perceptions of holism. This awareness is connected, naturally, to the real-world existence of libraries and collections of books, but the two are not identical. In Jewish culture (as well as in other cultures), library awareness is a diverse and fluid concept that changes with time and place. Differentiating stages or types of library awareness can contribute to an understanding of the historical, cultural, and intellectual trends of various periods. In this essay I will concentrate on the last two centuries, while touching as well on previous stages of Jewish culture....


2018 ◽  
Vol 64 (2) ◽  
pp. 172 ◽  
Author(s):  
Abraham Ortega ◽  
J. Juan Rosales

The fractional conformable derivative and its properties have been introduced recently. Using this derivative we obtain a new class of smooth solutions for the Newton’s law of cooling in terms of a stretched exponential function depending on the fractional order parameter 0 < γ ≤ 1. In addition, the convection coefficient of fractional order k(γ) can be calculated easily. Also, it is shown, that in the particular case γ = 1 these solutions become the ordi- nary ones.


Author(s):  
J.Z. Garrod

Although it is still in early stages, many commentators have been quick to note the revolutionary potential of next-generation or Bitcoin 2.0 technology. While some have expressed fear that the widespread application of these technologies may engender the rise of a Terminator-style Skynet, others believe that it represents the coming of a decentralized autonomous society (DAS) in which humans are freed from centralized forms of power through the proliferation of distributed autonomous organizations or DAOs. Influenced by neoliberal theory that stresses privatization, open markets, and deregulation, Bitcoin 2.0 technologies are implicitly working on the assumption that 'freedom' means freedom from the state. This neglects, however, that within capitalist societies, the state can also provide freedom from the vagaries of the market by protecting certain things from commodification. Through an analysis of (1) class and the role of the state; (2) the concentration and centralization of capital; and (3) the role of automation, I argue that the vision of freedom that underpins Bitcoin 2.0 tech is one that neglects the power that capital holds over us in both organizing the structure of our lives, and informing our idea of what it means to be human. In neglecting these other forms of power, I claim that the DAS might be a far more dystopian development than its supporters comprehend, making possible societies that are commodities all the way down.


Author(s):  
James Genone ◽  
Ian Van Buskirk

“Complex systems” are systems in which the independent behavior of interacting units gives rise to surprising and difficult-to-predict emergent patterns and properties. Most courses on complex systems focus on the behavior of ants, birds, clouds and other entities and use sophisticated mathematics to analyze these systems. Minerva’s course on complex systems is decidedly different. We start with an overview of characteristics of complex systems, but then quickly begin to apply them to how people and systems interact in the “real world.” Minerva’s Complex Systems course introduces students to the idea that most social systems are complex systems, and students learn to recognize that they are embedded in many different, overlapping complex social systems. Moreover, they learn to apply their understanding of these systems to social interactions—which informs, for example, the way they deal with ethical conflicts, debate, negotiation, and leadership. Approaching social interactions from the perspective of complex systems provides students with tools for understanding, anticipating and influencing outcomes of their interactions.


Sign in / Sign up

Export Citation Format

Share Document