Sensory Abnormalities in MS

2004 ◽  
Vol 6 (4) ◽  
pp. 144-147 ◽  
Author(s):  
Timothy Galey ◽  
Colleen Miller ◽  
Michael Nazareth ◽  
Rohit Bakshi ◽  
Carol M. Brownscheidle ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Spinal Cord ◽  
Lower Extremity ◽  
Disease Duration ◽  
The Body ◽  
Sensory Abnormalities ◽  
Patient Interviews ◽  
Body Regions ◽  
Edss Score

Sensory abnormalities such as numbness, paresthesias, and altered sensations of pain or temperature are common in MS. Using phenomenologic methodology, patient interviews were conducted to assess the occurrence of sensory abnormalities termed “macrosomatic illusions” in MS. These were defined as sensations of “largeness” accompanied by banding and/or tightness in specific body regions. These sensations were reported by 72 MS patients with mean disease duration of 4.7 years and mean EDSS score of 2.9. The phenomena usually affected more than one site: lower extremity (58 reports), torso (36 reports), upper extremity (26 reports), face (9 reports), and entire side of the body (4 reports). The sensations were variously described as “toes are like sausages,” “feels like I'm wearing clown shoes,” “like I have a tight corset on,” or “fingers feel swollen.” In five of seven patients for whom cervical MRI was available at the time of symptoms, lesions were identified in the spinal cord that correlated anatomically with the macrosomatic illusions. Longitudinal prospective studies are warranted to further characterize the prevalence and cause of these phenomena, their impact on disability and quality of life, and association with spinal cord disease.

scholarly journals Relationship between BODE index, quality of life and inflammatory cytokines in COPD patients

2009 ◽  
Vol 5 ◽  
Author(s):  
Nuhran Sarioglu ◽  
Aylin Ozgen Alpaydin ◽  
Aysın Sakar Coskun ◽  
Pınar Celik ◽  
Beyhan Cengiz Ozyurt ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Body Mass Index ◽  
Body Mass ◽  
Disease Duration ◽  
The Body ◽  
Chronic Obstructive ◽  
Bode Index ◽  
Copd Patients ◽  
Tnf Α

Background and aims: Recently a multidimensional grading system based on the body mass index (B), degree of airflow obstruction (O), dyspnea (D) and exercise capacity (E) - the BODE index - has begun to be used increasingly for the evaluation of chronic obstructive pulmonary disease (COPD) patients. The aim of our study was to investigate the relation- ship between the BODE index and disease duration, annual exacerbation and hospitalization rates, health related quality of life and systemic inflammatory markers like C-reactive protein (CRP), tumor necrosis factor (TNF)-α and interleukin (IL)-8. Materials and methods: In 88 stable COPD patients we evalu- ated the body-mass index, pulmonary function tests, Modified Medical Research Council dyspnea scale and six- minute walk test (6MWT). BODE scores were determined. Disease duration, number of exacerbations and hospitaliza- tion in the previous year were recorded. We also performed arterial blood gases analysis, administered the St. George’s Respiratory Questionnaire (SGRQ) and measured serum lev- els of CRP, TNF-α, IL-8. Results: According to BODE score 52% of patients were BODE 1, 21% BODE 2, 15% BODE 3 and 12% were BODE 4. There was a significant relationship between BODE index and COPD stage as classified according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) (p < 0.001). Correlations between BODE score and disease duration (p = 0.011), number of exacerbations (p < 0.001) and hospitaliza- tions (p < 0.001) in the last year were also observed. SGRQ symptom, activity, emotion scores and total scores were found to be significantly correlated to BODE (p < 0.001). Serum CRP levels and BODE were also correlated (p = 0.014); however, no correlation was found between serum levels of TNF-α and IL-8 and BODE. Conclusions: As the BODE index shows a strong correlation with various prognostic and follow up parameters of COPD and systemic inflammation, its use should be considered for the evaluation of COPD patients.

scholarly journals RELAÇÃO ENTRE DOR MUSCULOESQUELÉTICA E CONDIÇÕES DE TRABALHO DE POLICIAIS MILITARES

2020 ◽  
Vol 6 (2) ◽  
pp. 356-372
Author(s):  
Helen Caroline de Morais Santos ◽  
Fabiana Cury Viana ◽  
Deivid Kennedy da Silva
Keyword(s):  
Quality Of Life ◽  
Musculoskeletal Pain ◽  
Police Officers ◽  
Working Hours ◽  
The Body ◽  
Military Police ◽  
Work Activity ◽  
Body Regions ◽  
Lower Back

The military policeman's work activity can lead to musculoskeletal overload, due to long working hours, standing for many hours and the use of heavy equipment such as the ballistic vest, which can cause discomfort, fatigue and musculoskeletal pain, predisposing these professionals to pain. That compromise your health and quality of life. This study aimed to evaluate the perception of musculoskeletal pain of military police, identifying the presence of painful points and establishing relationships between the points found and their working conditions. Fifty-five military police officers of both sexes, with more than five years of service to the institution, who belonged to the 15th Battalion of the city of Patos de Minas-MG, participated in the study. The sociodemographic and health questionnaire was applied and, subsequently, the “Body Pain Map”. All police officers had pain in some region of the body after the workday. Associations between the body regions with pain, the use of the ballistic vest, work vehicle and length of service, showed involvement mainly in the lower back region. Given the results presented, there is a prevalence of pain in the lower back followed by pain in the thoracic region. All participants were wearing the ballistic vest, a fact that influenced the presence of the painful points presented. Therefore, studies are important in order to detect health risk factors for these workers, in order to propose strategies that improve their quality of life.

scholarly journals Half man, half prosthesis: the rehabilitation of people with hemicorporectomy – case series

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 298
Author(s):  
André Tadeu Sugawara ◽  
Milton Seigui Oshiro ◽  
Eduardo Inglez Yamanaka ◽  
Ronaldo Meneghetti ◽  
Dayrin Vanessa Tarazona Carvajal ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Spinal Cord ◽  
Social Inclusion ◽  
Functional Independence ◽  
The Body ◽  
World Health ◽  
World Health Organization Quality ◽  
Rehabilitation Process ◽  
Cord Injury

Hemicorporectomy is a procedure where the lumbar spine and spinal cord, pelvic bones and contents, lower extremities and external genitalia are surgically removed. The rehabilitation process, in addition to being prolonged and costly, is challenging. This article reports the rehabilitation process for hemicorporectomy and shows the innovative solutions for mobility for this disability for two cases of paraplegic patients: case 1 due to traumatic spinal cord injury due to firearm injury and case 2 due to lumbosacral myelomeningocele. They presented chronic pressure ulcer which evolved to neoplastic transformation. (squamous cell carcinoma - Marjolin's ulcer). The cases were submitted to L4 hemicorporectomy and were rehabilitated to ensure the right to mobility independence for activities of daily living; social inclusion; prevention of comorbidities and pluralization of disabilities. The rehabilitation involved the elaboration of a new prosthesis for the hemibody and improvement of functional capacity, within a gain of 6 - 11 points in the Functional Independence Measure (FIM). The principal changes happened in social interaction, locomotion and transfers to a bed/chair and toilet. Despite the body transformation, patients show gains in quality of life mainly for the social domain of World Health Organization Quality of Life instrument-brief version (WHOQOL-bref). In general, there is an increase in the scores of this instrument from 1.78% -19.25%. The evolution of social inclusion through the International Classification of Functioning, Disability and Health (ICF) reveals that patients are able to resume social, working, academic-professional life and recreation and leisure activities, reducing the number of severe and complete qualifiers from 90.91 to 60% when using the products appropriate assistive devices. Hemicorporectomy can be a therapeutic option for those in need, as it provides functionality without the need for caregivers and resumes educational, professional, economic and social aspects with gains in quality of life.

Experience in the use of double broncholytic therapy in occupational practice

2019 ◽  
pp. 303-307
Author(s):  
Elena A. Beigel ◽  
Natalya G. Kuptsova ◽  
Elena V. Katamanova ◽  
Oksana V. Ushakova ◽  
Oleg L. Lakhman
Keyword(s):  
Quality Of Life ◽  
Personal Data ◽  
The Body ◽  
Step Test ◽  
Aluminum Production ◽  
Chronic Obstructive ◽  
Body Plethysmography ◽  
Occupational Copd ◽  
The Impact

Introduction. Occupational chronic obstructive pulmonary disease (COPD) is one of the leading nosological forms of occupational respiratory disease. Numerous studies have shown high effectiveness of the combination of indacaterol/glycopyrronium (Ultibro®breezhaler®) on the impact on clinical and functional indicators in the treatment of COPD in General practice.The aim of the investigation the case of occupational COPD with the analysis of the dynamics of functional indicators, tolerance to physical load and evaluation of the quality of life of workers engaged in aluminum production by using combination of indacaterol/glycopyrronium.Materials and methods. The random sampling method included 20 men, workers of aluminum production, with the established diagnosis of professional COPD at the age of 40 to 60 years. The survey was conducted (Borg scale, medical Research Council scale (mMRC) and COPD Assessment Test (CAT). Functional methods of studies were conducted: spirometry, body plethysmography, electrocardiography (ECG) and the six-minute stepper test (6-MST).Results. Against the background of 8 weeks of therapy, the volume of forced exhalation for 1 minute (FEV1) increased by 14.7% and amounted to 67.90% of the due values, the forced vital capacity of the lungs (FVC) increased by 11.3% and amounted to 76.95% of the due. According to the body plethysmography (BPG) is set to decrease in residual lung volume on average by 13.4% and static hyperinflation, confirmed by the decrease in functional residual volume (FRV) of 18.8%. During the study period increased physical activity of patients. The average difference between the distance traveled in the six-minute step test before and after treatment was 58.8 m. The analysis of personal data showed that the quality of life of patients improved, the total score in the questionnaire CAT at the beginning of the study was 16.9 points, and after 8 weeks decreased by 63% and amounted to 10.7 points.Conclusions: The Results indicate a positive effect of combination therapy with indacaterol/glycopyrronium on the course and progression of occupational COPD.

Health related quality of life of rosacea patients in China assessed by DLQI and willingness to pay: Cross-Sectional Questionnaire Study (Preprint)

2020 ◽  
Author(s):  
Yaqun Huang ◽  
Sha Yan ◽  
Hongfu Xie ◽  
Ben Wang ◽  
Zhixiang Zhao ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Willingness To Pay ◽  
Disease Duration ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

BACKGROUND Rosacea is a chronic inflammatory dermatosis with facial skin involved, leading to physical and emotional problems, which greatly affected quality of life (QoL) of patients. Dermatology Life Quality Index (DLQI) and willingness to pay (WTP) are well-established instruments assessing the health-related quality of life (HRQoL), while very few studies have been focused on this topic about rosacea in China. OBJECTIVE To investigate HRQoL in Chinese rosacea patients assessed by DLQI and WTP and investigate potential predictors for patients with HRQoL severely affected. METHODS This cross-sectional study was conducted on 973 patients with rosacea. Sociodemographic data, clinical features and DLQI were collected, and WTP was assessed by three standardized items. Multivariable logistic analysis was performed to investigate independent factors influencing QoL. RESULTS 921 questionnaires were accomplished by participants. The mean DLQI score was 11.6 (median 11). Patients were willing to pay an average of $1050.2 or € 896.2 (median $431.4 or € 368.1) for complete cure. 33.3% would like to pay more than 20% of their monthly income to achieve sustainable control. There were positive correlations between WTP with DLQI (P < .05). DLQI could be independently impacted by age (21-30 and 31-40, OR = 3.242 and 3.617, respectively), the occupational requirement of appearance (high, OR = 4.410), disease duration (< 2 years, OR = 1.582), oedema (OR = 1.844) and severity of flushing, burning, stinging and pruritus (severe, OR = 2.003, 1.981, 2.491, 2.249, respectively). There were no significant associations between WTP and most of the clinical factors. CONCLUSIONS The QoL was negatively affected and should not be ignored among rosacea patients in China. Patients aged 21-40y, having occupational requirement of appearance, with the disease duration less than 2 years, and suffering severe flushing and related symptoms were more likely to have severe or very severe limitation of QoL.

Joint involvement influences quality of life in systemic lupus erythematosus patients

Lupus ◽  
2020 ◽  
pp. 096120332097903
Author(s):  
Francesco Natalucci ◽  
Fulvia Ceccarelli ◽  
Enrica Cipriano ◽  
Carlo Perricone ◽  
Giulio Olivieri ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lupus Erythematosus ◽  
Disease Duration ◽  
Joint Involvement ◽  
Systemic Lupus ◽  
Median Disease Duration ◽  
Group A ◽  
Musculoskeletal Manifestations ◽  
Group B

Introduction Joint involvement represents the major determinant in quality of life (QoL)in Systemic Lupus Erhytematosus (SLE) patients. However, QoLhas been generally evaluated by non-specific questionnaires. We evaluated the relationship between SLE musculoskeletal manifestations and QoL, assessed by LupusQoL. Methods Patients with joint involvement (group A) were compared with those without this feature (group B). Disease activity was assessed by SLEDAI-2k in the whole population, while DAS28 and swollen to tender ratio were applied to assess joint activity. LupusQoL was administered to all the patients. Results Group A included 110 patients [M/F 8/102; median age 49 years (IQR 13), median disease duration 156 months (IQR 216)], group B 58 [M/F 11/47; median age 40 years (IQR 15), median disease duration 84 months (IQR 108)].We found significanlty lower values in all the LupusQoL domains except for one (burden to others) in group A in comparison with group B. A significant correlation between DAS28 values and all the LupusQoL domains in group A was found; only three domains correlated with SLEDAI-2k. Conclusions SLE-related joint involvement significantly influences disease-specific QoL. DAS28 better correlated with LupusQoL domains in comparison with SLEDAI-2k, confirming the need for specific musculoskeletal activity indices.

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