Management Considerations for a Retained Plantar Knife Injury

A 13-year-old girl presented to the emergency department in stable condition with a retained penetrating knife wound injury in her right foot. Routine radiographs taken of the foot revealed deep tissue penetration by the knife without frank bony involvement. It was decided to remove the object in the operating room. Simple removal was performed, followed by wound exploration. The patient was admitted to the hospital for one night of observation and then was discharged without further complications.

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Improved Compliance with Universal Precautions among Operating Room and Emergency Department Personnel Following an Educational Intervention

PsycEXTRA Dataset ◽

10.1037/e359442004-011 ◽

1999 ◽

Cited By ~ 1

Author(s):

Lynn Kim ◽

◽

Rodney Parks ◽

Donna Jeffe ◽

Bradley Evanoff ◽

...

Keyword(s):

Emergency Department ◽

Operating Room ◽

Educational Intervention ◽

Universal Precautions

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Cost-Effectiveness of Initial Revision Digit Amputation Performed in the Emergency Department Versus the Operating Room

Hand ◽

10.1177/1558944718790577 ◽

2018 ◽

Vol 15 (2) ◽

pp. 208-214 ◽

Cited By ~ 1

Author(s):

Joseph A. Gil ◽

Avi D. Goodman ◽

Andrew P. Harris ◽

Neill Y. Li ◽

Arnold-Peter C. Weiss

Keyword(s):

Emergency Department ◽

Cost Effectiveness ◽

Operating Room ◽

Cost Effective ◽

Initial Management ◽

Fingertip Amputation ◽

Significant Difference ◽

Initial Procedure ◽

The Cost ◽

Cost Effectiveness Threshold

Background: The objective of this study was to determine the comparative cost-effectiveness of performing initial revision finger amputation in the emergency department (ED) versus in the operating room (OR) accounting for need for unplanned secondary revision in the OR. Methods: We retrospectively examined patients presenting to the ED with traumatic finger and thumb amputations from January 2010 to December 2015. Only those treated with primarily revision amputation were included. Following initial management, the need for unplanned reoperation was assessed and associated with setting of initial management. A sensitivity analysis was used to determine the cost-effectiveness threshold for initial management in the ED versus the OR. Results: Five hundred thirty-seven patients had 677 fingertip amputations, of whom 91 digits were initially primarily revised in the OR, and 586 digits were primarily revised in the ED. Following initial revision, 91 digits required unplanned secondary revision. The unplanned secondary revision rates were similar between settings: 13.7% digits from the ED and 12.1% of digits from the OR ( P = .57). When accounting for direct costs, an incidence of unplanned revision above 77.0% after initial revision fingertip amputation in the ED would make initial revision fingertip amputation in the OR cost-effective. Therefore, based on the unplanned secondary revision rate, initial management in the ED is more cost-effective than in the OR. Conclusions: There is no significant difference in the incidence of unplanned/secondary revision of fingertip amputation rate after the initial procedure was performed in the ED versus the OR.

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From emergency department to operating room

Current Opinion in Anaesthesiology ◽

10.1097/aco.0000000000001046 ◽

2021 ◽

Vol Publish Ahead of Print ◽

Author(s):

Levin Garip ◽

Angela L. Balocco ◽

Sam Van Boxstael

Keyword(s):

Emergency Department ◽

Operating Room

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Dual pH-triggered multistage drug delivery systems based on host–guest interaction-associated polymeric nanogels

Chemical Communications ◽

10.1039/c4cc03120b ◽

2014 ◽

Vol 50 (58) ◽

pp. 7824-7827 ◽

Cited By ~ 64

Author(s):

Minghui Zan ◽

Junjie Li ◽

Shizhong Luo ◽

Zhishen Ge

Keyword(s):

Drug Delivery ◽

Drug Release ◽

Drug Delivery Systems ◽

High Efficiency ◽

Delivery Systems ◽

Ph Responsive ◽

Tissue Penetration ◽

Deep Tissue ◽

Lysosomal Ph ◽

Tumor Acidity

The multistage polymeric nanogel delivery systems were constructed via host–guest interactions, which showed tumor acidity-triggered disassembly into smaller nanoparticles for deep tissue penetration, high-efficiency cellular uptake, and intracellular endo-lysosomal pH-responsive drug release.

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Near-IR-induced dissociation of thermally-sensitive star polymers

Chemical Science ◽

10.1039/c6sc04650a ◽

2017 ◽

Vol 8 (3) ◽

pp. 1815-1821 ◽

Cited By ~ 24

Author(s):

Yuqiong Dai ◽

Hao Sun ◽

Sunirmal Pal ◽

Yunlu Zhang ◽

Sangwoo Park ◽

...

Keyword(s):

Near Infrared ◽

Star Polymers ◽

Tissue Penetration ◽

Triggered Release ◽

Deep Tissue ◽

Responsive Systems ◽

Nir Light ◽

Near Ir ◽

Triggering Events ◽

Spatiotemporal Control

Responsive systems sensitive to near-infrared (NIR) light are promising for triggered release due to efficient deep tissue penetration of NIR irradiation relative to higher energy sources (e.g., UV), allowing for spatiotemporal control over triggering events with minimal potential for tissue damage.

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Inhibición de Crecimiento de Tumores de Cáncer de Próstata en Hipertermia Magnética mediada por Nanopartículas en Estudios Preclínicos: una Revisión de Alcance

10.24254/cnib.21.26 ◽

2021 ◽

Author(s):

◽

J. A. Parada Peralta

Keyword(s):

Prostate Cancer ◽

Tumor Growth ◽

Magnetic Nanoparticle ◽

Magnetic Hyperthermia ◽

Tumor Growth Inhibition ◽

Tissue Penetration ◽

Deep Tissue ◽

Incidence And Mortality ◽

Low Toxicity ◽

The Relationship

Prostate Cancer is one of the major concern types of cancer among men with respect to incidence and mortality. One relatively recent therapy against it, provided by Nanomedicine, is Nanoparticle mediated Magnetic Hyperthermia, which consists on tumor heating when exposed to an Alternating Magnetic Field in order to inhibit tumor growth (around 42 °C) (and make tumor sensible to other therapies: synergia) or to cause cancer cell apoptosis (greater temperature than 42°C). This procedure has several advantages like deep-tissue-penetration, targeted heating, low toxicity by Nanoparticles, and others. To this treatment, some of the Magnetic Nanoparticle properties are fundamental to its success, principaly the size, morphology, etc. Here, therefore, the relationship between the size of the employed Nanoparticles and the Tumor Growth Inhibition that cause is reviewed when treating Prostate Cancer tumors on mice models by Magnetic Hyperthermia.

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