Paired Exchanges, Chain Donations, and Organ Markets

2021 ◽  
pp. 84-87
Author(s):  
Martha Gershun ◽  
John D. Lantos
Keyword(s):  
Kidney Exchange ◽  
Graphic Presentation ◽  
Gray Market ◽  
Legal Questions ◽  
Serial Chain ◽  
Organ Markets ◽  
Paired Exchange ◽  
Kidney Liver

This chapter introduces the use of an innovation called “paired exchange,” a way to encourage donations even when there is no match. The chapter shows a graphic presentation to simply describe the idea of paired donation exchange. It explains the risks of paired exchange for the donors' and recipients' perspective, arguing that the risks were the same from the donors' perspective, while the outcomes from the recipients' perspective would be much better as a result of receiving a histocompatible organ than they would be if they received their own designated recipient's organ. The chapter also offers some legal questions after lawyers wondered whether a paired kidney exchange was a sort of barter and thus the beginning of a gray market in organs. Ultimately, the chapter looks at another suggestion of creating a serial chain of donor–recipient pairs, with the world's first kidney–liver swap took place in 2017.

The AMA Guides in Pennsylvania “Post-Protz”: Act 111 and Case Law Update

2020 ◽  
Vol 25 (3) ◽  
pp. 12-19
Author(s):  
Justin D. Beck ◽  
Judge David B. Torrey
Keyword(s):  
Case Law ◽  
General Assembly ◽  
Disability Benefits ◽  
Permanent Disability ◽  
Sixth Edition ◽  
Legal Questions ◽  
The Supreme Court ◽  
Recent Edition ◽  
Impairment Ratings

Abstract Medical evaluators must understand the context for the impairment assessments they perform. This article exemplifies issues that arise based on the role of impairment ratings and what edition of the AMA Guides to the Impairment of Permanent Impairment (AMA Guides) is used. This discussion also raises interesting legal questions related to retroactivity, applicability of prior precedent, and delegation. On June 20, 2017, the Supreme Court of Pennsylvania handed down its decision, Protz v. WCAB (Derry Area Sch. Dist.), which disallows use of the “most recent edition” of the AMA Guides when determining partial disability entitlement under the Pennsylvania Workers’ Compensation Act. An attempted solution was passed by the Pennsylvania General Assembly and was signed into law Act 111 on October 24, 2018. Although it affirms that the AMA Guides, Sixth Edition, must be used for impairment ratings, the law reduces the threshold for total disability benefits from 50% to 35% impairment. This legislative adjustment benefited injured workers but sparked additional litigation about whether, when, and how the adjustment should be applied (excerpts from the laws and decisions discussed by the authors are included at the end of the article). In using impairment as a threshold for permanent disability benefits, evaluators must distinguish between impairment and disability and determine an appropriate threshold; they also must be aware of the compensation and adjudication process and of the jurisdictions in which they practice.

INHIBITION OF THYROGLOBULIN BIOSYNTHESIS AND DEGRADATION BY EXCESS IODIDE. SYNERGISM WITH LITHIUM

1976 ◽  
Vol 81 (2) ◽  
pp. 495-506 ◽  
Author(s):  
A. Radvila ◽  
R. Roost ◽  
H. Bürgi ◽  
H. Kohler ◽  
H. Studer
Keyword(s):  
Protein Synthesis ◽  
Thyroid Gland ◽  
Inhibitory Action ◽  
Inhibit Protein Synthesis ◽  
Thyrotrophic Hormone ◽  
Thyroid Glands ◽  
Pre Treatment ◽  
Excess Iodide ◽  
Kidney Liver

ABSTRACT Lithium and excess iodide inhibit the release of thyroid hormone from preformed stores. We thus tested the hypothesis that this was due to an inhibition of thyroglobulin breakdown. Rats were pre-treated with propylthiouracil (PTU) for 3 weeks in order to deplete their thyroids of thyroglobulin. While the PTU was continued, lithium chloride (0.25 mEq./100 g weight) or potassium iodide (3 mg per rat) were injected every 12 h for 3 days. Thereafter the thyroglobulin content in thyroid gland homogenates was measured. PTU pre-treatment lowered the thyroglobulin content from 4.21 to 0.22 mg/100 mg gland. Lithium caused a marked re-accumulation of thyroglobulin to 0.60 mg/100 mg within 3 days. While iodide alone had only a borderline effect, it markedly potentiated the action of lithium and a combination of the two drugs increased the thyroglobulin content to 1.04 mg/100 mg. Thyroxine was injected into similarly pre-treated animals to suppress secretion of thyrotrophic hormone. This markedly inhibited the proteolysis of thyroglobulin and 1.3 mg/100 mg gland accumulated after 3 days. Excess iodide, given in addition to thyroxine, decreased the amount of thyroglobulin accumulated to 0.75 mg/100 mg gland. To study whether this could be explained by an inhibitory action of iodide on thyroglobulin biosynthesis, thyroid glands from animals treated with excess iodide were incubated in vitro in the presence of 0.2 mm iodide for 3 h. Iodide decreased the incorporation of radioactive leucine into total thyroidal protein and into thyroglobulin by 25 and 35 % respectively. Iodide did not inhibit protein synthesis in the kidney, liver or muscle tissue. Thus, large doses of iodide selectively inhibit thyroglobulin biosynthesis.

Digital risk analysis of cardiovascular diseases: new opportunities for the patients

2008 ◽  
Vol 149 (15) ◽  
pp. 677-684 ◽  
Author(s):  
Csaba Arnold ◽  
Zoltán Englert ◽  
Csaba Szabadhegyi ◽  
Csaba Farsang
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
Risk Analysis ◽  
Effective Treatment ◽  
Medical History ◽  
Vascular Diseases ◽  
Coronary Risk ◽  
Risk Status ◽  
Long Period ◽  
Graphic Presentation

Authors constructed a software helping the prevention programme of coronary and vascular diseases as the classical risk factors are used for graphic presentation of coronary risk as compared to “normal” risk. By repeated estimation alterations in coronary risk status can be compared to previous ones and thereby help evaluating the changes. This programme is highlighted by the presentation of changes in coronary risk of a patient during a 4-year-long period of her medical history. It is also shown how graphic presentation of risk can support the more effective treatment and patient care.

Dyskusja na temat odpowiedzialności odszkodowawczej państwa za szkody wyrządzone przez bezprawne działania urzędników na Kongresie Prawników Niemieckich w Kilonii w 1906 roku

2017 ◽  
Vol 15 (2) ◽  
pp. 131-146
Author(s):  
Andrzej Adamczyk
Keyword(s):  
19Th Century ◽  
Legal Regulations ◽  
Legal Problems ◽  
Legal Questions ◽  
German States ◽  
Illegal Acts ◽  
State Liability ◽  
German Reich ◽  
The 19Th Century ◽  
German Association

One of the most important legal problems discussed in the 19th century by German lawyers was that of state liability due to damages resulting from illegal acts of its officials. An influential forum of exchange of ideas was the German Association of German Jurists which organized all-German congresses to solve legal questions in order to promote German unity. Although the problem of state responsibility was discussed at some of the Association congresses in the 19th century, the most interesting was that held in Kiel in 1905. It was due to the fact that many German states had at that time legal regulations concerning state liability, but they were quite different. That generated many complications, making realization of a legal unity within the German Reich difficult. Two proposals for solving this situation were presented at the Congress in Kiel by Otto von Gierke and Rudolf von Herrnritt. Their ideas constituted bases for the discussion which followed. The paper presents the discussion on the state liability, which took place at the Congress in Kiel.

The Effect of Islamic Fundamental Regulations on Environ-mental Conservation Kesan Peraturan Asasi Islam pada Pemuliharaan Alam Sekitar

2015 ◽  
Vol 12 (1) ◽  
pp. 180-199
Author(s):  
Najmaldeen K. Kareem Al-Zanki ◽  
Kotb Rissouni
Keyword(s):  
Natural Resources ◽  
Public Interest ◽  
Environmental Conservation ◽  
Inductive Method ◽  
Legal Regulations ◽  
Environmental Preservation ◽  
Legal Questions ◽  
Universal Law ◽  
The Universe

AbstractThis study focuses on the legal regulations and jurisprudential dictates that are applicable to environmental conservation. The study employs an analytical and inductive method. It shows the set of regulations that apply to the concept of environmental preservation and then explains analytically how these regulations can legally accommodate questions pertaining to how humans address natural beings, natural resources and each component of the universe. The regulations such as the consideration of public interest, deeds' outcomes, customs, the elimination and compensation of damage and a means taking the value of its final objective will help in the adjustment of legal questions relevant to environmental conservation. The authors ensure that the universal laws and Sharī‘ah objectives must complement one another.                           . Keywords: Environmental Conservation, Sharī‘ah Regulations, Universal Law, Integrity of Universal and Divine Laws, Realization of Public Interest.AbstrakKajian ini memberi tumpuan kepada peraturan undang-undang dan jurisprudens yang berkaitan dengan pemuliharaan alam sekitar. Kaedah yang digunapakai dalam kajian ini adalah kaedah analisis dan induktif. Kajian ini menerangkan tentang peraturan yang dikenakan kepada konsep penjagaan alam sekitar dan kemudian menerangkan secara analisis bagaimana peraturan-peraturan ini secara sah boleh menjawab soalan mengenai bagaimana manusia menangani alam semula jadi, sumber asli dan setiap komponen alam semesta. Peraturan-peraturan yang berhubung dengan pertimbangan dan kepentingan awam, hasil perbuatan manusia, adat, penghapusan dan pampasan kerosakan dan cara mengambil nilai objektif akhirnya akan membantu dalam penyesuaian soal undang-undang yang berkaitan dengan pemuliharaan alam sekitar. Pengarang telah memastikan bahawa undang-undang universal dan objektif Sharī‘ah  Islam adalah saling melengkapi satu sama lain.Kata Kunci: Pemuliharaan Alam Sekitar, Peraturan Sharī‘ah, Undang-undang Universal, Integriti Undang-Undang Universal dan Agama, Merealisasikan Kepentingan Awam.

Kidney Exchange with Multiple Donors

2019 ◽  
Author(s):  
Oren Gilon ◽  
Tal Gilon ◽  
Assaf Romm
Keyword(s):  
Kidney Exchange ◽  
Multiple Donors

Reproductive rights: Legal aspects of the right to sterilisation

Stanovnistvo ◽  
2001 ◽  
Vol 39 (1-4) ◽  
pp. 119-130 ◽  
Author(s):  
Hajrija Mujovic-Zornic
Keyword(s):  
Mental Health ◽  
Free Choice ◽  
Reproductive Rights ◽  
German Law ◽  
Legal Aspects ◽  
Penal Policy ◽  
Abortion Law ◽  
Legal Questions ◽  
The Right ◽  
Voluntary Sterilization

In this paper the author discusses the nature and importance of the right to reproduce, in particular the right to sterilisation. In the time past sterilization has been practiced only as a measure of penal policy or the prevention of mental health diseases. Today, mostly we can speak about the right to sterilization (especially reversible sterilization). The patient have a free choice to decide any method of contraception and that could be a voluntary sterilization (also called human, contraceptive, non-therapeutical in French law, and obliging in German law). Various legal questions about this right can be raised, in accordance of state of reproductive rights (how they are regulated by the law) and the protection of reproductive rights (especially the right of pregnant woman as a patient). Yugoslav law not yet has a complete regulation and adequate solutions in this area, except the abortion law. The primary gynecology care has contraceptive counseling, but concrete measures and education are insufficient. It cannot begin to give consistent answers to all of these questions without a coherent conception of the right to reproduce, which is the primary duty of legal experts.

scholarly journals Author Correction: Assessment of nanoindentation in stiffness measurement of soft biomaterials: kidney, liver, spleen and uterus

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Guanlin Wu ◽  
Michael Gotthardt ◽  
Maik Gollasch
Keyword(s):  
Stiffness Measurement ◽  
Kidney Liver ◽  
Soft Biomaterials

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Sign in / Sign up

Export Citation Format

Share Document