scholarly journals Post-traumatic stress symptoms are associated with better performance on a delayed match-to-position task

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e4701 ◽  
Author(s):  
Meghan D. Caulfield ◽  
Catherine E. Myers
Keyword(s):  
Visual Discrimination ◽  
Traumatic Event ◽  
Reaction Times ◽  
Discrimination Performance ◽  
Spatial Separation ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
Match To Sample ◽  
Traumatic Memories

Many individuals with posttraumatic stress disorder (PTSD) report experiencing frequent intrusive memories of the original traumatic event (e.g., flashbacks). These memories can be triggered by situations or stimuli that reflect aspects of the trauma and may reflect basic processes in learning and memory, such as generalization. It is possible that, through increased generalization, non-threatening stimuli that once evoked normal memories become associated with traumatic memories. Previous research has reported increased generalization in PTSD, but the role of visual discrimination processes has not been examined. To investigate visual discrimination in PTSD, 143 participants (Veterans and civilians) self-assessed for symptom severity were grouped according to the presence of severe PTSD symptoms (PTSS) vs. few/no symptoms (noPTSS). Participants were given a visual match-to-sample pattern separation task that varied trials by spatial separation (Low, Medium, High) and temporal delays (5, 10, 20, 30 s). Unexpectedly, the PTSS group demonstrated better discrimination performance than the noPTSS group at the most difficult spatial trials (Low spatial separation). Further assessment of accuracy and reaction time using diffusion drift modeling indicated that the better performance by the PTSS group on the hardest trials was not explained by slower reaction times, but rather a faster accumulation of evidence during decision making in conjunction with a reduced threshold, indicating a tendency in the PTSS group to decide quickly rather than waiting for additional evidence to support the decision. This result supports the need for future studies examining the precise role of discrimination and generalization in PTSD, and how these cognitive processes might contribute to expression and maintenance of PTSD symptoms.

scholarly journals Genes and hormones of the hypothalamic–pituitary–adrenal axis in post-traumatic stress disorder. What is their role in symptom expression and treatment response?

2021 ◽  
Author(s):  
Susanne Fischer ◽  
Tabea Schumacher ◽  
Christine Knaevelsrud ◽  
Ulrike Ehlert ◽  
Sarah Schumacher
Keyword(s):  
Hpa Axis ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
Alternative Treatments ◽  
Hypothalamic Pituitary Adrenal ◽  
Post Traumatic

Abstract Background Less than half of all individuals with post-traumatic stress disorder (PTSD) remit spontaneously and a large proportion of those seeking treatment do not respond sufficiently. This suggests that there may be subgroups of individuals who are in need of augmentative or alternative treatments. One of the most frequent pathophysiological findings in PTSD is alterations in the hypothalamic–pituitary–adrenal (HPA) axis, including enhanced negative feedback sensitivity and attenuated peripheral cortisol. Given the role of the HPA axis in cognition, this pattern may contribute to PTSD symptoms and interfere with key processes of standard first-line treatments, such as trauma-focused cognitive behavioural therapy (TF-CBT). Methods This review provides a comprehensive summary of the current state of research regarding the role of HPA axis functioning in PTSD symptoms and treatment. Results Overall, there is preliminary evidence that hypocortisolaemia contributes to symptom manifestation in PTSD; that it predicts non-responses to TF-CBT; and that it is subject to change in parallel with positive treatment trajectories. Moreover, there is evidence that genetic and epigenetic alterations within the genes NR3C1 and FKBP5 are associated with this hypocortisolaemic pattern and that some of these alterations change as symptoms improve over the course of treatment. Conclusions Future research priorities include investigations into the role of the HPA axis in day-to-day symptom variation, the time scale in which biological changes in response to treatment occur, and the effects of sex. Furthermore, before conceiving augmentative or alternative treatments that target the described mechanisms, multilevel studies are warranted.

scholarly journals Association between Work-Related Trauma Exposure and Posttraumatic Stress Symptoms among Child Welfare Workers in Japan: A Cross-Sectional Study

2021 ◽  
Vol 18 (7) ◽  
pp. 3541
Author(s):  
Mayumi Kataoka ◽  
Daisuke Nishi
Keyword(s):  
Multivariate Analysis ◽  
Child Welfare ◽  
Traumatic Event ◽  
Traumatic Events ◽  
Child Welfare Workers ◽  
Cumulative Number ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
Work Related ◽  
Welfare Workers

Child welfare workers often experience work-related traumatic events and may be at risk of post-traumatic stress disorder (PTSD), which can hinder early interventions for child abuse. This study examined the association between each single work-related traumatic event experienced by child welfare workers and the cumulative number of traumatic event types with PTSD symptoms. A checklist of traumatic events was used to investigate work-related traumatic events. The PTSD checklist for DSM-5 (PCL-5) was used to screen for PTSD symptoms. Two multivariate analyses were performed. A total of 140 workers were included in the analyses. In the first multivariate analysis, the event, “Witnessed a parent violently beating, hitting, kicking, or otherwise injuring a child or the other parent during work” (β = 11.96; 95% CI, 2.11–21.80; p < 0.05) and resilience (β = −0.60; 95% CI, −0.84 to −0.36; p < 0.01) were significantly associated with PTSD symptoms, as was resilience in the second multivariate analysis (β = −0.60; 95%CI, −0.84 to −0.36; p < 0.01). The association between the cumulative number of event types and PTSD symptoms was not significant, but it was stronger when the cumulative number was four or more. The findings suggest the importance of reducing child welfare worker exposure to traumatic events.

scholarly journals Differential effect of Hurricane Sandy exposure on PTSD symptom severity: comparison of community members and responders

2019 ◽  
Vol 76 (12) ◽  
pp. 881-887 ◽  
Author(s):  
Adam Gonzalez ◽  
Rehana Rasul ◽  
Lucero Molina ◽  
Samantha Schneider ◽  
Kristin Bevilacqua ◽  
...  
Keyword(s):  
Symptom Severity ◽  
Differential Effect ◽  
Ptsd Symptom ◽  
Traumatic Event ◽  
World Trade Center ◽  
Hurricane Sandy ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
Community Members ◽  
Ptsd Symptom Severity

ObjectivesTo evaluate whether the association between Hurricane Sandy exposures and post-traumatic stress disorder (PTSD) symptom severity was greater for exposed community members compared with responders.MethodsData were analysed from three existing studies with similar methodologies (N=1648): two community studies, Leaders in Gathering Hope Together (n=531) and Project Restoration (n=763); and the Sandy/World Trade Center Responders Study (n=354). Sandy-related PTSD symptoms were measured using the PTSD checklist-specific traumatic event and dichotomised as elevated (>30) versus low/no (<30) PTSD symptoms. Sandy exposures were measured with a summed checklist. Multivariable logistic regression was performed to evaluate the differential effect of exposures on PTSD by responder status, adjusting for demographics and time elapsed since Sandy.ResultsResponders were somewhat older (50.5 years (SD=8.3) vs 45.8 years (SD=20.0)), more likely to identify as white (92.4% vs 48.1%) and were male (90.7% vs 38.4%). Responders were less likely to have elevated PTSD symptoms than community members (8.6% vs 31.1%; adjusted OR=0.28, 95% CI 0.17 to 0.46). While exposure was significantly related to elevated PTSD status, the effects were similar for responders and community members.ConclusionsResponders appear to be more resilient to PTSD symptoms post-Sandy than community members. Understanding the mechanisms that foster such resilience can inform interventions aimed at populations that are more vulnerable to experiencing PTSD after natural disasters.

Longitudinal associations between post-traumatic distress and depressive symptoms following a traumatic event: a test of three models

2010 ◽  
Vol 40 (10) ◽  
pp. 1669-1678 ◽  
Author(s):  
I. Schindel-Allon ◽  
I. M. Aderka ◽  
G. Shahar ◽  
M. Stein ◽  
E. Gilboa-Schechtman
Keyword(s):  
Depressive Symptoms ◽  
Structural Equation ◽  
Traumatic Event ◽  
Common Factor ◽  
Sem Analysis ◽  
Equation Modeling ◽  
Change Model ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
Post Traumatic

BackgroundSymptoms of post-traumatic stress disorder (PTSD) and depression are highly co-morbid following a traumatic event. Nevertheless, decisive evidence regarding the direction of the relationship between these clinical entities is missing.MethodThe aim of the present study was to examine the nature of this relationship by comparing a synchronous change model (PTSD and depression are time synchronous, possibly stemming from a third common factor) with a demoralization model (i.e. PTSD symptoms causing depression) and a depressogenic model (i.e. depressive symptoms causing PTSD symptoms). Israeli adult victims of single-event traumas (n=156) were assessed on measures of PTSD and depression at 2, 4 and 12 weeks post-event.ResultsA cross-lagged structural equation modeling (SEM) analysis provided results consistent with the synchronous change model and the depressogenic model.ConclusionsDepressive symptoms may play an important role in the development of post-traumatic symptoms.

scholarly journals PTSD and Suicidal Behaviors Amongst L'Aquila 2009 Earthquake Young Survivors

2021 ◽  
Vol 9 ◽  
Author(s):  
Claudia Carmassi ◽  
Carlo Antonio Bertelloni ◽  
Valerio Dell'Oste ◽  
Chiara Luperini ◽  
Donatella Marazziti ◽  
...  
Keyword(s):  
Suicidal Ideation ◽  
Suicide Attempts ◽  
Self Report ◽  
Ptsd Symptoms ◽  
Suicidal Behaviors ◽  
Post Traumatic Stress ◽  
Partial Group ◽  
Group 2 ◽  
Group 1

Background: Post-traumatic stress disorder (PTSD) is one of the most frequent and severe psychiatric consequences of natural disasters, frequently associated with suicidality. The aim of this study was at examining the possible relationships between suicidal behaviors and full-blown or partial PTSD, in a sample of young earthquake survivors. The second aim was at investigating the specific role of PTSD symptoms on suicidality.Methods: A total of 475 young adults who survived the L'Aquila 2009 earthquake, one of the most severe Italian disasters of the last decades, were recruited and assessed after 21 months from the catastrophe. Participants were evaluated by two questionnaires assessing subthreshold psychopathology, the Trauma and Loss Spectrum Self-Report (TALS-SR) to investigate both full and partial PTSD, and two specific Mood Spectrum Self-Report (MOODS-SR) sub-domains exploring suicidality, namely suicidal ideation and suicide attempts.Results: The ensuing findings showed that suicidal ideation and suicide attempts were present, respectively, in 40 (8.4%) and 11 (2.3%) survivors. Rates of suicidal ideation were significantly more elevated in full-blown PTSD subjects (group 1), as compared with those suffering from partial (group 2) or no PTSD (group 3). Interestingly, group 2 subjects showed significantly more suicidal ideation than healthy individuals, and less than those of group 1, while the frequency of suicide attempts was similar across the three groups. Suicidal ideation was associated with higher scores in the following TALS-SR domains: grief-reactions, re-experiencing, avoidance and numbing, maladaptive coping, and personal characteristics/risk factor.Conclusions: The results of the present study support and extend previous findings on the role of PTSD symptoms in suicidality after a severe earthquake. However, as compared with available literature, they also highlight the significant impact of sub-threshold PTSD manifestations in increasing the suicide risk in survivors of a mass disaster.

scholarly journals Eye Movement Desensitization and Reprocessing (EMDR) Therapy for Handling Post Traumatic Stress Disorder (PTSD) Respondents

2015 ◽  
Vol 30 (2) ◽  
pp. 65-74
Author(s):  
Eka Susanty ◽  
Setyono Koesno ◽  
Candra Yudhistira ◽  
Lulu Lusianti ◽  
Suprijanto Suprijanto
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Traumatic Event ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
Symptom Scale ◽  
Before And After ◽  
Post Traumatic ◽  
Emdr Therapy ◽  
Ptsd Prevalence

EMDR therapy is designed to reduce distress related traumatic event. PTSD prevalence is large enough in Indonesia. It was caused by many natural disasters that happened in several area of Indonesia. However, the application of EMDR for reducing PTSD symptoms was still rare. The objective of this study was to examine the intervention of EMDR therapy in handling PTSD respondents and using a one group pretest-posttest design. There were nine PTSD respondents involved during treatment. EMDR treatments were conducted in four repetitive sessions. Each session was completed in 60-90 minutes. Data was taken using PSS (PTSD Symptom Scale) and tested with Wilcoxon statistical analysis. The statistic test showed (Z = - 2.668; p = .05) with Asymp. Sig. =.008. Descriptive data showed that mean scores before and after therapy are 30.88 and 15.77 respectively. This research concluded that EMDR therapy can work to decrease PTSD symptoms.

scholarly journals Cleaner wrasse indirectly affect the cognitive performance of a damselfish through ectoparasite removal

2018 ◽  
Vol 285 (1874) ◽  
pp. 20172447 ◽  
Author(s):  
Sandra A. Binning ◽  
Dominique G. Roche ◽  
Alexandra S. Grutter ◽  
Simona Colosio ◽  
Derek Sun ◽  
...  
Keyword(s):  
Cognitive Abilities ◽  
Visual Discrimination ◽  
Negative Impact ◽  
Cognitive Impairments ◽  
Discrimination Performance ◽  
Innate Immune ◽  
Discrimination Test ◽  
Pomacentrus Amboinensis ◽  
Spatial Recognition

Cleaning organisms play a fundamental ecological role by removing ectoparasites and infected tissue from client surfaces. We used the well-studied cleaning mutualisms involving the cleaner wrasse, Labroides dimidiatus, to test how client cognition is affected by ectoparasites and whether these effects are mitigated by cleaners. Ambon damselfish ( Pomacentrus amboinensis) collected from experimental reef patches without cleaner wrasse performed worse in a visual discrimination test than conspecifics from patches with cleaners. Endoparasite abundance also negatively influenced success in this test. Visual discrimination performance was also impaired in damselfish experimentally infected with gnathiid (Crustacea: Isopoda) ectoparasites. Neither cleaner absence nor gnathiid infection affected performance in spatial recognition or reversal learning tests. Injection with immune-stimulating lipopolysaccharide did not affect visual discrimination performance relative to saline-injected controls, suggesting that cognitive impairments are not due to an innate immune response. Our results highlight the complex, indirect role of cleaning organisms in promoting the health of their clients via ectoparasite removal and emphasize the negative impact of parasites on host's cognitive abilities.

scholarly journals Brazilian Jiu Jitsu Training for US Service Members and Veterans with Symptoms of PTSD

2019 ◽  
Vol 184 (11-12) ◽  
pp. e626-e631
Author(s):  
Alison E Willing ◽  
Sue Ann Girling ◽  
Ryan Deichert ◽  
Rebecca Wood-Deichert ◽  
Jason Gonzalez ◽  
...  
Keyword(s):  
Traumatic Event ◽  
Significant Proportion ◽  
The United States ◽  
Active Duty ◽  
South Florida ◽  
Self Report ◽  
Service Members ◽  
Routine Practice ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress

Abstract Introduction The United States has been actively involved in major armed conflicts over the last 15 years. As a result, a significant proportion of active duty service personnel and returning veterans have endured combat, putting them at risk for developing post-traumatic stress disorder (PTSD), a disabling disorder that may occur after exposure to a traumatic event. Current therapies often require long-term, time-intensive and costly commitment from the patient and have variable degrees of success. There remains an ongoing need for better therapies, including complementary medicine approaches that can effectively reduce PTSD symptoms. While anecdotal evidence suggests that routine practice of Brazilian Jiu Jitsu (BJJ) can reduce symptoms of PTSD, there have been no formal studies to address this. Materials and Methods This study was approved by the University of South Florida Institutional Review Board (#PRO00019430). Male US active duty service members and veterans from the Tampa area participated in a 5-month (40 sessions) BJJ training program. Before beginning and again midway through and upon completion of training the participants completed several validated self-report measures that addressed symptoms of PTSD and other co-morbid conditions. Effect size and 95% confidence intervals were determined using a within-person single-group pretest–posttest design. Results Study participants demonstrated clinically meaningful improvements in their PTSD symptoms as well as decreased symptoms of major depressive disorder, generalized anxiety and decreased alcohol use; effect sizes varied from 0.80 to 1.85. Conclusions The results from this first-of-kind pilot study suggest that including BJJ as a complementary treatment to standard therapy for PTSD may be of value. It will be necessary to validate these promising results with a larger subject cohort and a more rigorous experimental design before routinely recommending this complementary therapy.

scholarly journals Protagonist Role of Opioidergic System on Post-Traumatic Stress Disorder and Associated Pain

2020 ◽  
Vol 17 (6) ◽  
pp. 506-516
Author(s):  
Marjan Nikbakhtzadeh ◽  
Fatemeh Mohtashami Borzadaran ◽  
Elham Zamani ◽  
Mohammad Shabani
Keyword(s):  
Chronic Pain ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Pain Reduction ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
Opioidergic System ◽  
Post Traumatic

Objective Post-traumatic stress disorder (PTSD) and chronic pain often co-occur. Studies have shown an interaction between pain and PTSD. In this narrative review, we aim to support conducting comprehensive studies by describing PTSD, pain and determining whether opioidergic system, its agonist and antagonist manipulation could positively or negatively affect PTSD symptoms and concurrent pain.Methods Term searches was done in Google Scholar, Scopus, ScienceDirect, Web of Science and PubMed databases as well as hand searching in key resource journals from 1979–2019.Results There are a lot of contradictions and disputes when endogenous opioidergic system and opioidergic antagonist system are studied in PTSD patients. Exogenous morphine administration in PTSD patients can decrease the symptoms of PTSD but it doesn’t have a pain reduction effect to an acceptable level. Beta-endorphin as an endogenous opioid is effective in pain reduction in the moment of events but after minutes to hours, the endorphins withdrawal syndrome leads to exaggerated intrusive thoughts and flashbacks of PTSD, which exacerbate the pain. It has also been shown that naloxone, as an opioidergic antagonist, can reduce or increase the PTSD symptoms and its associated pain.Conclusion Data suggest different roles of opioidergic system and their antagonist in pain control and mood in PTSD. However, further investigations need to be done in order to reveal the role of endogenous opioidergic system and opioidergic antagonist system as a mediator in PTSD patients suffering from acute or chronic pain.

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