Uremic Pruritus: Prevalence and Impact on Quality of Life and Depressive Symptoms in Hemodialysis Patients

Objective The purpose of this study was to determine how burden and quality of life predict anxiety and depressive symptoms among caregivers of hemodialysis patients. Social support was included in the model as a proposed moderator in the above relationships. Methods This cross-sectional study involved 340 caregivers of chronic kidney patients undergoing hemodialysis. The setting was in Terengganu, Malaysia. The caregivers completed the measures of caregiving burden, quality of life, social support, and symptoms of anxiety and depression. Results About 28.8% and 52.4% of caregivers showed clinically moderate levels of anxiety and depressive symptoms, respectively. Furthermore, 35.9% and 3.8% of them showed clinically high levels of anxiety and depressive symptoms, respectively. Analyses showed that general quality of life was a significant predictor of both anxiety and depressive symptoms. Burden and psychological domains of quality of life significantly predicted anxiety. In addition, a lack of social support was a determinant of depressive symptoms. Evidence suggested that social support moderated the burden–anxiety relationship. Specifically, caregivers with low levels of social support showed more elevated levels of anxiety symptoms when their burden was higher. Conclusion There is an urgent need for early detection to initiate prompt treatment in this population. The study provides some important insights into offering comprehensive intervention to help caregivers cope more effectively through the provision of sufficient social support to buffer the effects of caregiving burden and improve mental health.

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Nutritional Status Evaluated by Multi-Frequency Bioimpedance Is Not Associated With Quality of Life or Depressive Symptoms in Hemodialysis Patients

Therapeutic Apheresis and Dialysis ◽

10.1111/j.1744-9987.2010.00874.x ◽

2010 ◽

Vol 15 (1) ◽

pp. 58-65 ◽

Cited By ~ 6

Author(s):

Annerose Barros ◽

Bartira E. Pinheiro da Costa ◽

Carlos E. Poli-de-Figueiredo ◽

Ivan C. Antonello ◽

Domingos O. d'Avila

Keyword(s):

Quality Of Life ◽

Depressive Symptoms ◽

Nutritional Status ◽

Hemodialysis Patients

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Two Sides of the Same Coin: The Positive and Negative Impact of Spiritual Religious Coping on Quality of Life and Depression in Dialysis Patients

Journal of Holistic Nursing ◽

10.1177/0898010117725429 ◽

2017 ◽

Vol 36 (4) ◽

pp. 332-340 ◽

Cited By ~ 6

Author(s):

Luciano Magalhães Vitorino ◽

Renata de Castro e Santos Soares ◽

Ana Eliza Oliveira Santos ◽

Alessandra Lamas Granero Lucchetti ◽

Jonas Preposi Cruz ◽

...

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Depressive Symptoms ◽

Religious Coping ◽

Depressive Symptomatology ◽

Short Form ◽

Hemodialysis Patients ◽

Sf 36 ◽

Two Sides

Background: Studies have shown that spiritual/religious beliefs are associated with mental health and health-related quality of life (HRQoL). However, few studies evaluated how spiritual/religious coping (SRC) could affect hemodialysis patients. Objectives: The present study investigated the role of SRC behaviors on HRQoL and depressive symptoms in hemodialysis patients. Design and Participants: This was cross-sectional study with 184 patients. Patients completed the Beck Depression Inventory, Brief SRC Scale, Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36), and a Sociodemographic and Health Characterization Questionnaire. Results: From 218 patients, 184 (84.4%) were included (53.8% male with a median age of 55.9 years). Negative SRC, but not positive SRC, was associated with depressive symptoms. Positive SRC presented significant effects in SF-36 pain and physical and social functioning. On the other hand, negative SRC exhibited significant effects in SF-36 role emotional, energy/fatigue, pain, and physical functioning. Conclusion: SRC influences the mental health and HRQoL in Brazilian hemodialysis patients in two distinct ways. If used positively, it may have positive outcomes. However, if used negatively, it may lead to dysfunctional consequences such as greater depressive symptomatology and affect HRQoL. Health professionals must be aware of these “two sides of the same coin.”

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The effect of music therapy on hemodialysis patients' quality of life and depression symptoms

Brazilian Journal of Nephrology ◽

10.1590/2175-8239-jbn-2018-0023 ◽

2019 ◽

Vol 41 (1) ◽

pp. 74-82 ◽

Cited By ~ 1

Author(s):

Paula de Marchi Scarpin Hagemann ◽

Luis Cuadrado Martin ◽

Carmen Maria Bueno Neme

Keyword(s):

Quality Of Life ◽

Depressive Symptoms ◽

Music Therapy ◽

Hemodialysis Patients ◽

Therapeutic Interventions ◽

Depression Symptoms ◽

Music Production ◽

Treatment And Prevention ◽

Before And After

ABSTRACT Introduction: The sources of stress involved in chronic kidney disease (CKD) can lead to depressive states, directly affecting the hemodialysis patient's quality of life (QOL). There are few reports and studies on therapeutic interventions that aim to minimize depressive symptoms in these patients and an even greater shortage of studies using music therapy. Objective: This study evaluated the effect of music therapy on QOL and depressive symptoms in hemodialysis patients. Method: This was a music therapy intervention study in which 23 patients were evaluated regarding QOL and depression symptoms at two distinct stages - before and after the intervention. Eight sessions of music therapy were conducted, with two weekly sessions and an average duration of 75 minutes. The intervention was conducted by the music therapist herself, using specific music therapy techniques, besides voice and guitar to conduct harmonic and rhythmic support for the groups' sound-music production. Results: The patients showed a significant reduction in depression symptoms (p < 0.001) and better QOL results, with significant differences in the following dimensions: functional capacity (p = 0.011), pain (p = 0.036), general health (p = 0.01), vitality (p = 0.004), mental health (p = 0.012), symptom and problem list (p = 0.01), and overall health (p = 0.01). Conclusions: Intervention with music therapy constitutes an effective option in the treatment and prevention of depressive symptoms and improved QOL of HD patients.

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Effects of Thermotherapy on the Quality of Life and Biochemical Parameters in Hemodialysis Patients with Uremic Pruritus

10.53350/pjmhs211572123 ◽

2021 ◽

Vol 15 (7) ◽

pp. 2123-2127

Author(s):

Hamed Zare ◽

Majideh Heravi Karimooi ◽

Nahid Rejeh ◽

Hamid Sharif Nia ◽

Nader Noori Majelan

Keyword(s):

Quality Of Life ◽

Biochemical Parameters ◽

Intervention Group ◽

Far Infrared ◽

Hemodialysis Patients ◽

Control Group ◽

Common Symptom ◽

Uremic Pruritus ◽

Experimental Group

Introduction and objective: Uremic pruritus is a common symptom in patients under hemodialysis. The exact cause of uremic pruritus is not yet known. Although effective treatments are available, there is not still a commonly accepted treatment for this disorder. The present study was aimed at examining the effects of thermotherapy on the quality of life (QOL) and biochemical parameters in hemodialysis patients with uremic pruritus. Patients and methods: In this experimental study, a total of 40 men under hemodialysis suffering from uremic pruritus were randomly selected and divided into an experimental group (thermotherapy) and a control group (no exposure to heat). The experimental group were exposed to far-infrared radiation (FIR) at 40 °C in 15-minute sessions, three times a week, in total for 18 sessions. The Severity of Pruritus Scale (SPS), the Kidney Disease Quality of Life Instrument (KDQOL), and the ItchyQoL were completed by the participants before the start of intervention, one month after the start of intervention, and at the end of intervention. The data were analyzed using SPSS22. Results: Significant differences were observed between the intervention and control groups in all the criteria for assessing uremic pruritus, including history of symptoms, daily activities, QOL, effects on sleep, emotional aspects, and severity of pruritus (p<0.001). In addition, significant improvements were found after the intervention in the criteria for assessing the QOL of the patients (p<0.001). Moreover, improvements in the calcium and phosphorus levels were observed in the intervention group in comparison with the control group. Conclusion: Thermotherapy is effective in reducing the severity of pruritus and increasing the QOL of patents with this problem. Therefore, it can be used as a complementary method in treating patients with uremic pruritus who also experience a reduction in their QOL. Keywords: Hemodialysis, Thermotherapy, Uremic pruritus, Quality of life, Biochemical parameters

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Are Resistance Training-Induced BDNF in Hemodialysis Patients Associated with Depressive Symptoms, Quality of Life, Antioxidant Capacity, and Muscle Strength? An Insight for the Muscle–Brain–Renal Axis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph182111299 ◽

2021 ◽

Vol 18 (21) ◽

pp. 11299

Author(s):

Lysleine Alves Deus ◽

Hugo de Luca Corrêa ◽

Rodrigo Vanerson Passos Neves ◽

Andrea Lucena Reis ◽

Fernando Sousa Honorato ◽

...

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Depressive Symptoms ◽

Resistance Training ◽

Antioxidant Capacity ◽

Hemodialysis Patients ◽

Rating Of Perceived Exertion ◽

Dialysis Session ◽

Thiobarbituric Acid Reactive Substance

Background: Hemodialysis patients are suffering from depressive symptoms. Brain-derived neurotrophic factor (BDNF) levels are negatively associated with depressive symptoms and decrease during a single hemodialysis session. Resistance training (RT) might be an additional non-pharmacological tool to increase BDNF and promote mental health. Methods: Two randomized groups of hemodialysis patients: control (CTL, n = 76/F36; 66.33 ± 3.88 years) and RT (n = 81/F35; 67.27 ± 3.24 years). RT completed six months of training thrice a week under the supervision of strength and conditioning professional immediately before the dialysis session. Training loads were adjusted using the OMNI rating of perceived exertion. The total antioxidant capacity (TROLOX), glutathione (GSH), thiobarbituric acid reactive substance (TBARS), and BDNF levels were analyzed in serum samples. Quality of life (assessed through Medical Outcomes—SF36), and Beck Depression Inventory was applied. Results: RT improved handgrip strength (21.17 ± 4.38 vs. 27.17 ± 4.34; p = 0.001) but not for CTL (20.09 ± 5.19 vs. 19.75 ± 5.54; p = 0.001). Post-training, RT group had higher values as compared to CTL related to TROLOX (RT, 680.8 ± 225.2 vs. CTL, 589.5 ± 195.9; p = 0.001) and GSH (RT, 9.33 ± 2.09 vs. CTL,5.00 ± 2.96; p = 0.001). RT group had lower values of TBARS as compared to CTL at post-training (RT, 11.06 ± 2.95 vs. CTL, 13.66 ± 2.62; p = 0.001). BDNF increased for RT (11.66 ± 5.20 vs. 19.60 ± 7.23; p = 0.001), but decreased for CTL (14.40 ± 4.99 vs. 10.84 ± 5.94; p = 0.001). Quality of life and mental health increased (p = 0.001) for RT, but did not change for CTL (p = 0.001). BDNF levels were associated with emotional dimensions of SF36, depressive symptoms, and handgrip (p = 0.001). Conclusions: RT was effective as a non-pharmacological tool to increased BDNF levels, quality of life, temper the redox balance and decrease depressive symptoms intensity in hemodialysis patients.

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Cathartic Effect of Suicide Attempts Not Limited to Depression

Crisis ◽

10.1027//0227-5910.24.2.73 ◽

2003 ◽

Vol 24 (2) ◽

pp. 73-78 ◽

Cited By ~ 21

Author(s):

Yves Sarfati ◽

Blandine Bouchaud ◽

Marie-Christine Hardy-Baylé

Keyword(s):

Quality Of Life ◽

Depressive Symptoms ◽

Personality Traits ◽

Rating Scales ◽

Suicide Attempts ◽

World Health ◽

Life Questionnaire ◽

Short Term

Summary: The cathartic effect of suicide is traditionally defined as the existence of a rapid, significant, and spontaneous decrease in the depressive symptoms of suicide attempters after the act. This study was designed to investigate short-term variations, following a suicide attempt by self-poisoning, of a number of other variables identified as suicidal risk factors: hopelessness, impulsivity, personality traits, and quality of life. Patients hospitalized less than 24 hours after a deliberate (moderate) overdose were presented with the Montgomery-Asberg Depression and Impulsivity Rating Scales, Hopelessness scale, MMPI and World Health Organization's Quality of Life questionnaire (abbreviated versions). They were also asked to complete the same scales and questionnaires 8 days after discharge. The study involved 39 patients, the average interval between initial and follow-up assessment being 13.5 days. All the scores improved significantly, with the exception of quality of life and three out of the eight personality traits. This finding emphasizes the fact that improvement is not limited to depressive symptoms and enables us to identify the relative importance of each studied variable as a risk factor for attempted suicide. The limitations of the study are discussed as well as in particular the nongeneralizability of the sample and setting.

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