scholarly journals Measles Neutralization Antibodies and Some Related Factors in Women of Reproductive-age in Hanoi, Vietnam

Author(s):  
Than Huu Dao ◽  
Loan Phuong Do ◽  
Anh Kieu Thi Nguyen ◽  
Satoshi Inoue ◽  
Katsuhiro Komase ◽  
...  

Aims: Our study aimed to determine neutralization antibodies against measles virus and some related factors in women of childbearing-age from 18 to 30 years old, in Hanoi, Vietnam. Methodology: In 2018, a cross-sectional study was conducted on 1,235 childbearing-age women from 18-30 years old in Bavi district, Hanoi, Vietnam. The study participants were interviewed by using a structured questionnaire which included demographic information, and history of measles. The measles neutralization antibodies (MNA) of these participants were quantified by a plaque reduction neutralization test (PRNT). The data were analyzed using the Epidata 3.1 and Stata 14.2 software. Results: The results showed that only 58.5% had MNA at sufficient protective levels (≥120mIU/ml), up to 12.5% were negative for MNA, and 358 women (29%) had MNA at insufficient protective levels. In addition, we found that the participants’ working as public employees, having two children, and being ≥ 25 years of age were all positively associated with the sufficient protective antibody levels (P<0.05). A weak positive correlation between age and MNA titers was determined (r= 0.26). Conclusion: Approximately half (41.5%) of the women of childbearing age in this study did not have sufficient protective antibodies against measles virus. The study results suggest that it is necessary to boost measles vaccine to prevent the sporadic measles infection in women of childbearing age in Hanoi and to quantify the dynamics of maternal measles antibody levels in infants born from these women, so as to provide evidences to control measles incidence in children up to 9 months of age in the future.

2019 ◽  
Vol 46 (1) ◽  
pp. 59-66
Author(s):  
Jue Liu ◽  
Min Liu ◽  
Shikun Zhang ◽  
Qiuyue Ma ◽  
Qiaomei Wang

IntroductionChina’s one-child policy was replaced by a new universal two-child policy in 2015; however, few studies have addressed the intent to have a second child and resulting related issues.MethodsWe performed a cross-sectional study on 11 991 Chinese women, 18–49 years of age, from 11 provinces in 2016–2017, in order to assess the intent for a second child among Chinese women of childbearing age and other related factors after the introduction of China’s new universal two-child policy.ResultsWe found that the overall prevalence of the intent to have a second child was 39.4% and that economic, childrearing, and health barriers affected fertility intent. Multivariate logistic regression models showed that the age range of 25–39 years (aOR 1.28–1.30), living in Eastern (aOR 1.28, 95% CI 1.10 to 1.50) or Central China (aOR 1.52, 95% CI 1.27 to 1.78), living in a rural area (aOR 1.62, 95% CI 1.47 to 1.78), being a farmer (aOR 1.43, 95% CI 1.09 to 1.88), having a higher household income (aOR 1.13, 95% CI 1.00 to 1.28), having a history of abortion (aOR 1.18, 95% CI 1.05 to 1.31), and already having one child (aOR 3.65 for girls, aOR 2.70 for boys) were associated with a greater intent to have a second child (all p<0.05). Conversely, economic, health, childrearing, and educational barriers were associated with a lower intent to have a second child (aOR 0.65–0.75).ConclusionFour in ten women of childbearing age demonstrated an intent for a second child. We maintain that fertility-related factors be given full consideration when promoting the two-child policy.


2020 ◽  
pp. 201010582095872
Author(s):  
Roghieh Bayrami ◽  
Alireza Didarloo ◽  
Afsaneh Asadinejad

Purpose: Although preconception care (PCC) has been integrated into women’s care programmes in the country for more than a decade, it has not yet been welcomed by Iranian women, and the rate of PCC uptake is very low. Therefore, this study aims to determine predictors of uptake of PCC based on the Beliefs, Attitudes, Subjective Norms and Enabling Factors (BASNEF) model among women of reproductive age referred to health centres in Urmia, Northwest Iran, in 2019. Methods: This cross-sectional study was carried out on 230 women of childbearing age at Urmia health centres during 2019. Subjects were selected using a multistage sampling method. A valid reliable researcher-made questionnaire, including demographic information, items related to the BASNEF model constructs regarding PCC and items related to PCC behaviour, was used to collect data. Data were analysed using descriptive and inferential statistics (frequencies, means and standard deviations, independent t-test, chi-square test, logistic and linear regression). Results: The findings showed that the rate of receiving PCC was 19.6%. Overall, the BASNEF model predicted 42% of the intention to receive health care. Among the model constructs, enabling factors (β=0.32, p<0.001) and attitude (β=0.41, p<0.001) significantly explained women’s behavioural intention towards receiving PCC. In the logistic regression model, intention (β=0.15, p<0.001) and enabling factors (β=0.12, p=0.034) had a significant role in predicting PCC. Conclusion: The low uptake of PCC by women of childbearing age in Urmia suggests the need to design and implement interventions based on women’s attitudes, intentions and enabling factors in order to stimulate and maintain women’s health-promoting behaviours during childbearing age.


2021 ◽  
Vol 9 (01) ◽  
pp. 74-86
Author(s):  
Sharmila Pokharel ◽  
Ram Krishna Maharjan

Antenatal care is one of the most effective measures to reduce maternal mortality in Lower Middle-income Countries. The study aims to assess the utilization of antenatal care and related factors by breastfeeding mothers in Chitwan district of Nepal. A cross-sectional study was carried out in Bharatpur municipality in April 2020, among all women of the reproductive age group (15-49) who have had a birth child in the last 12 months before the survey date. A census sampling technique was used to select respondents. The vaccination period was two weeks. All the mothers who came to the vaccine center to vaccinate their children were the respondents of this study. The data were collected by using an interview schedule. The collected data were managed using SPSS Version 20. The study found that 84.31 percent of respondents attended more than four antenatal care utilization. The educational level of the respondents and the occupation of their partners were linked to the use of antenatal care. The number of pregnancies, the number of live births, the place of delivery, and the educational level and occupations of the birth attendees were also significantly linked to the use of antenatal care. Community mobilization and intensive use of community health workers are essential factors to improve the use of antenatal care.


2020 ◽  
Vol 70 (700) ◽  
pp. e778-e784
Author(s):  
Elizabeth Lovegrove ◽  
John Robson ◽  
Patricia McGettigan

BackgroundThe teratogenic risks of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are well documented, but prescribing these in younger women in primary care is becoming increasingly frequent.AimTo record how frequently women of childbearing age, who are prescribed an ACE inhibitor or ARB, receive preconception advice and/or are prescribed contraception, and how many pregnancies, terminations, and miscarriages occur in this population. Additionally, to ascertain whether patterns in the above differ across age groups.Design and settingCross-sectional study conducted among patients from 141 general practices in East London.MethodWomen aged 15–45 years who were issued a prescription for an ACE inhibitor or ARB between 1 October 2018 and 1 January 2019 inclusive were included. An electronic search strategy was designed to extract pseudonymised data concerning preconception and contraception advice, contraception, and pregnancies from the electronic clinical system; this was applied to the selected cohort on 1 January 2019. Data were analysed in 5-year age groups.ResultsOf 302 939 women aged 15–45 years, 2651 (0.9%) were prescribed an ACE inhibitor or an ARB in a 3-month period. Of these, 2159 (81.4%) had no advice and no contraception prescription recorded, 35 (1.3%) had preconception advice recorded, and 230 (8.7%) had contraception advice recorded. A total of 100 pregnancies and 21 terminations/miscarriages were recorded in the 12 months preceding the index date (1 January 2019).ConclusionThis study found that the recording of pre-pregnancy advice and contraception in women of childbearing age who were prescribed an ACE inhibitor or an ARB was suboptimal; this may place women and their babies at risk of exposure to teratogens during pregnancy. The findings indicate that there is a need for improved safety strategies based in primary care.


BMJ Open ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. e030873 ◽  
Author(s):  
Rihwa Choi ◽  
Yejin Oh ◽  
Youngju Oh ◽  
Sung Ho Kim ◽  
Sang Gon Lee ◽  
...  

ObjectivesThe aim of this study was to investigate the immunity against rubella using the serological status of rubella-specific IgG antibodies (antirubella IgG) in Korean women of childbearing age (15–49 years).DesignRetrospective cross-sectional study.SettingPopulation-based cross-sectional study in South Korea.ParticipantsBetween January 2010 and December 2017, test results from Korean women aged 15–49 years who had visited an obstetric private clinic (nationwide institutions) and had requested rubella-specific IgG antibody tests from Green Cross Laboratories were obtained from the laboratory information system.ResultsBetween 2010 and 2017, antirubella IgG test results from 328 426 Korean women aged 15–49 years who had visited private obstetric clinics (1438 institutions nationwide) were retrospectively analysed by tested year, age, cohort and geographic regions. Over the 8-year study period, the rate of unimmunised women ranged from 7.8% to 9.7%. Multivariable-adjusted logistic regression models showed that the odds of being immune to rubella (positive and equivocal results of antirubella IgG test) were lower in 2017 compared with 2010, in women in their 40s, in a pre-catch-up cohort and in women living in Incheon, Busan, South Gyeongsang, North and South Jeolla and Jeju provinces (p<0.0001).ConclusionsIn consideration of the factors associated with prevalence of women unimmunised to rubella, future public health efforts should be focused on catch-up activities. The results of this study could be used to strengthen disease control and prevent rubella, including a nationwide immunisation programme.


PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0155801 ◽  
Author(s):  
Minxue Shen ◽  
Hongzhuan Tan ◽  
Shujin Zhou ◽  
Ravi Retnakaran ◽  
Graeme N. Smith ◽  
...  

2010 ◽  
Vol 4 (5) ◽  
pp. 217
Author(s):  
Suhartono Suhartono ◽  
Dharminto Dharminto

Wanita bermukim di daerah pertanian berisiko terpajan pestisida yang dapat berakibat hipotiroidisme yang pada kehamilan dapat menyebabkan gangguan tumbuh-kembang janin. Tujuan penelitian ini adalah mengetahui angka kejadian keracunan pestisida dan hipotiroidisme pada wanita usia subur di daerah pertanian. Penelitian ini menggunakan disain penelitian cross-sectional dan 26 WUS terpilih sebagai subjek secara acak. Semua subjek dilakukan pengukurankadar TSH, fT4 dan enzim kolinesterase, sementara kadar T3, UEI, dan Pb darah diukur pada sub-sampel. Penderita dinyatakan keracunan pestisida apabila ditemukan kadar enzim kolinesterase <3,9 μg/L dan dinyatakan hipotiroidisme apabila kadar TSH >4,5 μIU/L. Penelitian ini menemukan rerata kadar kolinesterase adalah 7,26 (±1,28) dengan kisaran nilai 5,33-9,39 μg/L; rerata kadar TSH adalah 5,09 (±6,14), dengan kisaran nilai 0,47-31,73μIU/L; rerata kadar fT4 adalah 15,18 (±2,09), dengan kisaran nilai 8,73-18,87 pmol/L; rerata kadar T3 adalah 1,75 (±0,51), dengan kisaran nilai 1,24-2,95 pmol/L. Prevalensi keracunan pestisida pada WUS 0,0% dan prevalensi hipotiroidisme 46,2%.Kata kunci : Pestisida, hipotiroidisme, wanita usia subur, daerah pertanianAbstractWomen lived in agricultural areas are risk to suffer various disorders due to pesticides exposure such as hypothyroidism. Hypothyroidism causes growth and development disorders of fetus. The aim of the study is to find out the prevalence of pesticide poisoning and hypothyroidism in women of childbearing age in agricultural areas. Cross-sectional study was conducted and 26 women of childbearing age were selected randomly. TSH, fT4 and cholinesterase enzymelevels were measured in all subjects, while levels of T3, UEI and blood Pb were measured in the sub-sample. Pesticide poisoning is determined if the levels of enzymes cholinesterase <3.9 μg/L and determined as hypothyroidism if the TSH >4.5 μIU/L. This study showed that mean of cholinesterase levels was 7.26 (± 1.28), range of values 5.33-9.39 μg/L; mean of TSH levels was 5.09 (± 6.14), range of values 0.47-31.73 μIU/L; mean of fT4 level was 15.18 (±2.09), range of values 8.73-18.87 pmol/L; mean of T3 levels was 1.75 (±0.51), range of values 1.24-2.95 pmol/L. The prevalence of pesticide poisoning in childbearing women was 0.0% and prevalence of hypothyroidism was 46.2%.Key words : Pesticide, hypothyroidism, women of childbearing age, agricultural area


2020 ◽  
Vol 18 (1) ◽  
pp. 103-107
Author(s):  
Arun Sedhain ◽  
Gandhi R Bhattarai ◽  
Sanjaya Raya Yadav ◽  
Bhupendra Raj Pandey ◽  
Thakur Prasad Pant

Background: Vitamin D deficiency is a common problem in many countries throughout the world. This study aimed at understanding the status of vitamin D deficiency in relation to age, gender, geography and season among relatively bigger numbers of population residing in central and western regions of Nepal.Methods: This retrospective cross-sectional study was carried out by reviewing the records of vitamin D tests in two centers of Nepal- namely united reference laboratories at Pokhara and Chitwan Medical College at Chitwan. A total of 3320 individuals who were tested for clinical suspicion of vitamin D deficiency over a period of one year were included in the study. Results: Mean vitamin D level was 18.7 ng/mL. Majority of subjects tested for vitamin D were females (71.36 %) with female to male ratio of 2.49:1. Hypovitaminosis D (? 30 ng/mL) was found in 84.5% subjects and was moderate to severely deficit (<10 ng/mL) in 25.9% of subjects. Status of hypovitaminosis D was found to be less in ?50 years (79.9%) than the younger subjects (89.9% in ?18 years and 87.0% in 19-49 years age group). Vitamin D deficiency was found lower in hills districts (80.8% vs 89.7% in the plains), which was found to be more pronounced during winter through summer seasons as compared to fall season.Conclusions: Population residing in plain areas and summer, spring and winter season are found to have increased problem of Hypovitaminosis D. It is also found to be common among younger children and female of reproductive age group. We have also found out the increased problem of hypovitaminosis D among population residing in the plain areas than in the hills especially in the summer, spring and winter season.Keywords: Geographic variation; hypovitaminosis D; Nepal


2020 ◽  
Vol 10 (04) ◽  
pp. 369-392
Author(s):  
Christelle Momdjo M’bobda ◽  
Judith Laure Ngondi ◽  
Françoise Raïssa Ntentie ◽  
Boris Ronald Tonou Tchuente ◽  
Maxwell Wandji Nguedjo ◽  
...  

2020 ◽  
Author(s):  
Elham Kor ◽  
Seyed Reza Saadat Mostafavi ◽  
Zahra Ahmadian Mazhin ◽  
Adeleh Dadkhah ◽  
Anis Kor ◽  
...  

Abstract Objectives: About 10-15% of women of childbearing age have endometriosis. The present study aimed to investigate the relationship between the severity of symptoms of endometriosis and the spread as well as the stage of the disease on ultrasonography. The present cross-sectional study evaluates the relationship between the severity of endometriosis symptoms and the spread of disease on ultrasonography in patients with endometriosis.Results: Considering different analyses, the cumulative size of posterior Deep Infiltrative Endometriosis (DIE) (less than 1 cm) is significantly correlated with minimal severity of dyspareunia and chronic pelvic pain. The incidence of dyspareunia was more prevalent in patients with complete stenosis of Douglas pouch than those with incomplete stenosis. Furthermore, the incidence of severe and very severe pain in patients with Douglas pouch stenosis is relatively higher than that in patients without stenosis. Only dyspareunia is related to the stage of endometriosis, and patients with dyspareunia are five times more at risk of a higher stage of the disease. The severity of dyspareunia is related to the stage of endometriosis and the severity of Douglas pouch stenosis. The results showed a correlation between chronic pelvic pain and r-ASRM score (revised American Society for Reproductive Medicine score).


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