Response Properties of Optic Flow Neurons in the Accessory Optic System of Hummingbirds vs. Zebra Finches and Pigeons

Optokinetic responses function to maintain retinal image stabilization by minimizing optic flow that occurs during self-motion. The hovering ability of hummingbirds is an extreme example of this behaviour. Optokinetic responses are mediated by direction-selective neurons with large receptive fields in the accessory optic system (AOS) and pretectum. Recent studies in hummingbirds showed that, compared to other bird species, (i) the pretectal nucleus lentiformis mesencephali (LM) is hypertrophied, (ii) LM has a unique distribution of direction preferences, and (iii) LM neurons are more tightly tuned to stimulus velocity. In this study, we sought to determine if there are concomitant changes in the nucleus of the basal optic root (nBOR) of the AOS. We recorded the visual response properties of nBOR neurons to largefield drifting random dot patterns and sine wave gratings in Anna's hummingbirds and zebra finches and compared these with archival data from pigeons. We found no differences with respect to the distribution of direction preferences: Neurons responsive to upwards, downwards and nasal-to-temporal motion were equally represented in all three species, and neurons responsive to temporal-to-nasal motion were rare or absent (<5%). Compared to zebra finches and pigeons, however, hummingbird nBOR neurons were more tightly tuned to stimulus velocity of random dot stimuli. Moreover, in response to drifting gratings, hummingbird nBOR neurons are more tightly tuned in the spatio-temporal domain. These results, in combination with specialization in LM, supports a hypothesis that hummingbirds have evolved to be "optic flow specialist" to cope with the optomotor demands of sustained hovering flight.

Photon Force MEMS cantilever combined with fibre optic system as a measurement technique for optomechanical studies

In this paper we present a metrological measurement technique that is a combination of fibre optic interferometry and a microelectromechanical system (MEMS) sensor for photon force (PF) measurement with traceability via an electromagnetic way. The main advantage of the presented method is the reference to the current balance, which is the primary mass/force metrological standard. The MEMS cantilever is a transducer of the photon force to the deflection that can be compensated with the use of the Lorentz force. This movement is measured with the use of the interferometer and does not require any mechanical calibration. Combining the MEMS current balance system with the interferometry is then the unique and fully metrological solution. The resolution of the proposed measurement technique is calculated to be 4 pN//Hz^(0.5) (2% uncertainty). The PF–MEMS used for the investigation is the cantilever with the resolution of 46 fN/Hz0.5, which was calculated from the thermomechanical noise, and is far below the whole system resolution limit. As far as the whole construction is based on the fibre optic system, it does not require any complex adjustment procedure and may work as an optomechanical reference in any metrological laboratory.

DEVELOPMENT OF OPTICAL TRANSDUCER ON FABRICS FOR THE APPLICATION OF LIQUID CLUSTERING USING REFLECTANCE SPECTROSCOPY

Recently, usage of fabrics as wearable device, along with their applications are increasing, one example being the detection of bio-analyzes such as blood or sweat. One method used to observe the properties of the material of a fabric is to use the Refcletance Spectroscopy, in which excitation of monochromatic light with a specific wavelength is given to a fabrics. Intensity value is then processed using the PCA method in order to obtain the pattern of the difference between each substrate. The proposed transducer optic system consists of 405nm blueviolet laser as the light source, biconvex lens, Adafruit AS7262 light detector, and Arduino. This system can only detect the difference in substrate content from the occurring light scatter. This system can be applied to various kinds of fabric wearable material with differing scatter intensity values depending on the kind of fabrics. Softer kind of fabric is proposed as material for the wearable device because it gives a high scatter intensity value and constant values in every repetation which results in better data reading.Keywords: clustering, optical, reflectance, spectroscopy, transducer, wearable.

Influence of Two-Frequency Radiation Intensity Fluctuations on the Output Signal of a Vortex Optical Fiber Forming OAM Address in Polyharmonic Sensor Technology

A schematic diagram of a RoF radio-optic system with vortex signals is presented, in which the radio frequency is determined by the difference between the wavelengths of two lasers. It is assumed that the generation of a vortex signal can be performed through a vortex fiber-optic periodic structure, which can be obtained using a technology similar to the manufacture of long-period fiber Bragg gratings. The parameters of the grating are modeled assuming that the fundamental light-guide mode (LP01) is applied to the specified vortex element, and the higher-order mode (LP11) is reflected. It was found that the distortion of the vortex signal can be reduced by introducing apodization and chirping of this periodic structure. The following optimal parameters have been estimated: the apodization and chirp multiplier functions, at which the distortions of the amplitude and phase of the vortex signal, as well as the appearance of an unwanted angle distortion, will be minimal. It is shown that such gratings can be exploited in addressed sensors systems using the orbital angular momentum (OAM) of a lightwave as a unique sensor address.

Epigenetics, 1-Carbon Metabolism, and Homocysteine During Dysbiosis

Although a high-fat diet (HFD) induces gut dysbiosis and cardiovascular system remodeling, the precise mechanism is unclear. We hypothesize that HFD instigates dysbiosis and cardiac muscle remodeling by inducing matrix metalloproteinases (MMPs), which leads to an increase in white adipose tissue, and treatment with lactobacillus (a ketone body donor from lactate; the substrate for the mitochondria) reverses dysbiosis-induced cardiac injury, in part, by increasing lipolysis (PGC-1α, and UCP1) and adipose tissue browning and decreasing lipogenesis. To test this hypothesis, we used wild type (WT) mice fed with HFD for 16 weeks with/without a probiotic (PB) in water. Cardiac injury was measured by CKMB activity which was found to be robust in HFD-fed mice. Interestingly, CKMB activity was normalized post PB treatment. Levels of free fatty acids (FFAs) and methylation were increased but butyrate was decreased in HFD mice, suggesting an epigenetically governed 1-carbon metabolism along with dysbiosis. Levels of PGC-1α and UCP1 were measured by Western blot analysis, and MMP activity was scored via zymography. Collagen histology was also performed. Contraction of the isolated myocytes was measured employing the ion-optic system, and functions of the heart were estimated by echocardiography. Our results suggest that mice on HFD gained weight and exhibited an increase in blood pressure. These effects were normalized by PB. Levels of fibrosis and MMP-2 activity were robust in HFD mice, and treatment with PB mitigated the fibrosis. Myocyte calcium-dependent contraction was disrupted by HFD, and treatment with PB could restore its function. We conclude that HFD induces dysbiosis, and treatment with PB creates eubiosis and browning of the adipose tissue.