MICRO-CRACK ANALYSIS IN THE STUDY OF FATIGUE FRACTURE IN THE HAZ IN THE HIGH YIELD STRENGTH MICRO-ALLOYED STEELS

Various applications have been described in the literature for the High-Strength and Low-Alloy steels (HSLA) industry, analysing their use both in industrial and marine equipment and machines and in structures that require appropriate resilience values and toughness at low temperatures. For successful operation under conditions as large structures under extreme service conditions, it is essential to ensure the proper toughness both in base metal (USITEN 355 0.5 Ni Grade I steel) and in the heat-affected area of the weld. (ZAC). This research carries out Crack Tip Opening Displacement (CTOD) tests, showing, in this article, the first part of the test corresponding to fatigue pre-cracking and a summary table of the results of fracture toughness, to guarantee that, under the conditions which exist in welding, both the fatigue fracture values and the fracture toughness are acceptable by the applicable standards. Keywords: SMAW, weld line, CTOD, stress intensity factor, input heat energy, crack growth rate, fatigue fracture, fracture toughness

OSov: An Interactive Web Server to Evaluate Prognostic Biomarkers for Ovarian Cancer

Ovarian cancer is one of the most aggressive and highly lethal gynecological cancers. The purpose of our study is to build a free prognostic web server to help researchers discover potential prognostic biomarkers by integrating gene expression profiling data and clinical follow-up information of ovarian cancer. We construct a prognostic web server OSov (Online consensus Survival analysis for Ovarian cancer) based on RNA expression profiles. OSov is a user-friendly web server which could present a Kaplan–Meier plot, forest plot, nomogram and survival summary table of queried genes in each individual cohort to evaluate the prognostic potency of each queried gene. To assess the performance of OSov web server, 163 previously published prognostic biomarkers of ovarian cancer were tested and 72% of them had their prognostic values confirmed in OSov. It is a free and valuable prognostic web server to screen and assess survival-associated biomarkers for ovarian cancer.

Fluorescent Chemosensors Based on Polyamine Ligands: A Review

Polyamine ligands are water-soluble receptors that are able to coordinate, depending on their protonation degree, either metal ions, anionic, or neutral species. Furthermore, the presence of fluorescent signaling units allows an immediate visual response/signal. For these reasons, they can find applications in a wide variety of fields, mainly those where aqueous media is necessary, such as biological studies, wastewater analysis, soil contamination, etc. This review provides an overview of the recent developments in the research of chemosensors based on polyamine ligands functionalized with fluorescent signaling units. The discussion focuses on the design, synthesis, and physicochemical properties of this type of fluorescent chemosensors in order to analyze the applications associated to the sensing of metal ions, anions, and neutral molecules of environmental and/or biological interest. To facilitate a quick access and overview of all the chemosensors covered in this review, a summary table of the chemosensor structures and analytes, with all the corresponding references, is also presented.

The persuasion of vaccine allocation models during Covid-19. Rhetoric, ethics and science

The swift development of effective vaccines against the new coronavirus was an unprecedented scientific achievement. In this paper, we discuss what models have been proposed for distributing vaccines locally and globally through the application of Aristotelian rhetoric. This discussion, therefore, focuses on a specific question: how are the different models of vaccine administration and distribution justified on an ethical-argumentative level? This report also examines what has come to be known as “vaccine nationalism” through the lens of the early experience with the COVID- 19 vaccination process. To this end, this report proceeds as follows: Section I explains the rhetorical method applied to ethical principles, and Section II explains the chosen criteria for the analysis. Section III looks at the Fair Priority Model; Section IV examines the COVAX and GAVI model; Section V presents the weighted lottery model. Section VI proposes a summary table of the analysis of the proposed models and Section VII focuses on the ethical problem of vaccine nationalism and its implications in relation to the models, that were taken into consideration during the previous sections. Section VIII offers brief conclusions; solidarity conceived as an argument of reciprocity should be, according to this analysis, the guiding value to address ethical problems in the area of resource allocation.

Determination of horizontal stress orientation in the areas of the Tomsk region

Introduction. The World Stress Map project proves that horizontal stress orientation determination is a global task essential for the majority of geomechanical calculations. However, there is scant data on stress orientations in the territory of Russia at the moment. The task is therefore highly relevant. Research objective is to determine the orientations of maximum and minimum horizontal stresses by separate areas of the Tomsk region and build a map of horizontal stresses. Method of research. The basis for determining the orientations of horizontal stresses is the theory of drilling-induced fracture and borehole breakouts occurrence. The maximum stress orientation coincides with the drilling-induced fracture orientation, whereas the minimum stress orientation coincides with the borehole breakouts orientation or is perpendicular to the maximum stresses. Results. Research results are compiled in a summary table containing mean orientations of horizontal stresses by areas and a map of horizontal stress orientations. Conclusions. A summary map of maximum horizontal stress strike azimuths has been constructed. The stresses are of similar orientation in every well under consideration, except for a well in the North-Shingin area. The average value of maximum horizontal stress orientation has made up 337° northwest and 157° southeast.

Production Performance Analysis of Volga-Ural Mature Waterflood with PRIME Diagnostic Metrics

The paper presents a practical case of production performance analysis at one of the mature waterflood oil fields located at the Volga-Ural oil basin with a large number of wells. It is a big challenge to analyse such a large production history and requires a systematic approach. The main production complication is quite common for mature waterflood projects and includes non-uniform sweep, complicated by thief injection and thief water production. The main challenge is to locate the misperforming wells and address their complications. With the particular asset, the conventional single production analysis techniques (oil production trend, watercut trend, reservoir and bottom-hole pressure trend, productivity trend, conventional pressure build-up surveys and production logging) in the vast majority of cases were not capable of qualifying the well performance and assessing of remaining reserves status. The performance analysis of such an asset should be enhanced with new diagnostic tools and modern methods of data integration. The current study has made a choice in favor of using a PRIME analysis which is multi-parametric analytical workflow based on a set of conventional and non-conventional diagnostic metrics. The most effective diagnostics in this study have happened to be those are based on 3D dynamic micro-models, which are auto-generated from the reservoir data logs. PRIME also provided useful insights on well performance, formation properties and the current conditions of drained reserves which helped to select the candidates for infill drilling, pressure maintenance, workovers, production target adjustments and additional surveillance. The paper illustrates the entire PRIME workflow, starting from the top-level field data analysis, all the way to generating a summary table containing well diagnostics, justifications and recommendations.

Integration of ethnoscience in problem-based learning to improve contextuality and meaning of biology learning

Meaningful learning can be carried out by adapting learning to local culture and traditions. Ethnoscience is a set of knowledge identified in a community and can be used as the learning base to create contextual and meaningful learning for students. This study aims to find more information about ethnoscience-based biology learning. The research method used was a literature study. The literature used mainly discusses ethnoscience, ethnoscience learning, and learning methods. The instrument used in this study was a summary table of all related articles, following the summary table made by Cronin et al. (2008). This research produces a new conceptual framework which is a synergy between ethnoscience and problem-based learning. This research also generates six procedures for designing ethnoscience-based learning and five steps to integrate ethnoscience into Problem-based Learning. The integration of ethnoscience in problem-based learning can increase the contextuality and meaning of biology learning and can be applied to maintain local culture. This study recommends the use of procedures resulted from this study to design ethnoscience-based learning and integrate ethnoscience learning into Problem-Based Learning.