Multiple perspectives integration for virtual reality-aided assemblability assessment in narrow assembly spaces

Virtual reality (VR) has been proved as a promising tool for industrial design, but the traditional VR interface of first-person perspective (1PP) is not efficient to support assemblability assessment in narrow assembly spaces. In this paper, we proposed the multi-perspectives interface (MPI) which integrates the 1PP and the third-person perspective (3PP) using the handheld world-in-miniature (WIM). The MPI allows users to simulate the assembly operations in a natural manner similar to 1PP, while providing users with an overview of the assembly status through the WIM to assess the assemblability with superior spatial awareness. Two studies were conducted to test the performance of the proposed MPI. The first study tested user’s interaction performance in MPI using a common interaction task, which reveals stronger spatial awareness in MPI than in 1PP without the cost of losing natural interaction. Based on the results of the first study, the second study tested the performance, usability, and workload of MPI in an assemblability assessment task. The results show the advantages of MPI in the reachability evaluation in the narrow spaces. The main contribution of this paper is improving the interface and user-interface interaction in VR-aided assembly assessment system to improve user’s interaction performance and assessment ability in narrow assembly spaces.

Comprehensive study on unipolar RRAM charge conduction and stochastic features, a simulation approach

An in-depth analysis of resistive switching (RS) in unipolar devices is performed by means of a new simulator based on resistive circuit breakers of different features. The forming, set and reset processes are described in terms of the stochastic formation and rupture of conductive filaments of several branches in the dielectric. Both, the electric field and temperature dependencies are incorporated in the simulation. The simulation tool was tuned with experimental data of devices fabricated making use of the Ti/HfO2/Si stack. The variability and the stochastic behavior are characterized and reproduced correctly by simulation to understand the physics behind RS. Reset curves with several current steps are explained considering the rupture of different branches of the conductive filament. The simulation approach allows to connect in a natural manner to compact modeling solutions for the devices under study.

Examining the Significance of Internal Mobility Hiring in Determining the Individual Vs Organizational Outcomes: An Empirical Investigation from ADNOC FURSA Platform During Recent Pandemic of COVID-19

Objective Scope: ADNOC group of companies introduced the Fursa platform which is an internal online website where HR acquisition partners among the 13 companies can post vacancies and employees from any of the 13 companies can apply to those vacancies. The aim of this initiative is to move ADNOC's employees internally to reskill, fill department gaps, and cross-collaborate to get a project done or hit an organizational goal with minimizing hiring cost and accelerate recruitment process. This study considers the above stated program as an explanatory factor to determine the individual's as well as organizational outcomes in ADNOC group of companies. Methods, Procedure, Process: To address the study objectives, qualitative and quantitative methods are adopted. More specifically, for quantitative approach, structural questionnaire was developed through adopting different items from the literature. Whereas qualitative analysis are conducted while using the information from structured interviews. Results, Observations, Conclusions: The study findings indicates that both individual and organizational outcomes are positively and significantly determined by internal mobility program. Similarly, analyses through qualitative approach confirms that internal mobility program helps to provide learning and development of the employees, productivity and performance in terms of individual outcomes, and sales and growth to reflect the concept of organizational outcomes. It is stated current program Enabled employees to find their next position, project, or mentor internally, and maximized ADNOC workforce potential and unlock the capacity to meet the corporate objectives. Other interesting outcomes are It takes less time and money to source (and saves money on relocation costs and as known during pandemic situation there is a restriction on international movement between countries); it enables faster onboarding and ramping up. Additionally, during internal mobility the company is confident that the candidate shares your mission and vision, and It also implies that you are aware of a candidate's most recent performance. Novel/Additive information: the study is unique in the sense that it is done in one of the giant oil and gas companies which employees working in different aspects of the business; upstream, downstream, and mid-stream. The study introduces modern ways of work in a speedy, natural manner, and the use of MS Teams to do virtual interviews. Fursa platform allows companies to act quickly. It only takes a few seconds to determine where talent should be directed, and a few more seconds to deploy it.

Higher-level Inferences in the Strong-Kleene Setting: A Proof-theoretic Approach

Building on early work by Girard (1987) and using closely related techniques from the proof theory of many-valued logics, we propose a sequent calculus capturing a hierarchy of notions of satisfaction based on the Strong Kleene matrices introduced by Barrio et al. (Journal of Philosophical Logic 49:93–120, 2020) and others. The calculus allows one to establish and generalize in a very natural manner several recent results, such as the coincidence of some of these notions with their classical counterparts, and the possibility of expressing some notions of satisfaction for higher-level inferences using notions of satisfaction for inferences of lower level. We also show that at each level all notions of satisfaction considered are pairwise distinct and we address some remarks on the possible significance of this (huge) number of notions of consequence.

Metagenome Profiling of Anterior Uterine Samples to Improve in-vitro Fertilization Success Ratio

Background: The radical increase in the number of couples experiencing infertility, which is the inability to conceive in a natural manner, has increased the interest among the researchers worldwide to identify the root cause for this problem. Relevant studies are needed to ascertain the cause behind unexplained infertility, and certain interventions are needed in the process of assisted reproductive technology to improve the implantation success. The presence of certain pathogenic flora in the cervix and vaginal region are often attributed to the failure of In-vitro fertilization (IVF), which is a method of assisted reproduction. This study explored the cervix and vaginal microbiota of 52 such infertile females who underwent assisted reproduction (IVF), to analyse the microbiota, identify pathogenic flora and evaluate the diversity of the flora.Methods: 52 microbial swab samples of infertile females were sequenced using 16s rRNA approach. 16s rRNA data analysis was performed to get the taxonomic abundance and pathogenicity of the resultant microbiota. The microbial communities were statistically assessed for probable similarities and differences between positive, negative and not applicable outcomes of IVF.Results: A total of 31 genera were identified across the study samples, and a thorough investigation of associated pathogenicity of these taxa was performed. Certain pathogenic genera specific to positive as well as negative implantation were observed. Additionally, the alpha diversity was observed to be higher in the cervical region compared to the vaginal region. Rarefaction analysis was performed. The analysis of beta diversity was performed and the phylogenetic distance was visualized through distance boxplots. Conclusion: The presence of pathogenic bacteria, especially those associated with conditions like Bacterial Vaginosis and Chronic Endometritis, are often linked to infertility conditions and were predominant in the cervical and vaginal samples. Dysbiosis in the cervical and vaginal region is often attributed to decrease in Lactobacillus spp. and increase in other species, leading to difference in functionalities and growth of pathogens. In this study, the presence of pathogenic organisms in both regions was remarkable. Additionally, large bacterial diversity in cervical regions was observed, which might be a possible reason for implantation failure. Further studies on the mechanism of action of these bacteria is needed; the possible sources of contamination, such as the tip of the catheter during embryo transfer, the DNA extraction kits prior to sequencing, etc. need to be identified as this might introduce pathogens during the procedure. By using more sterility in the procedure as well as profiling the metagenome of the infertile female, novel insights can be gained as well as a more directed procedure can be performed to increase the chances of success in implantation.

Milk Exosomes Transfer Oligosaccharides into Macrophages to Modulate Immunity and Attenuate Adherent-Invasive E. coli (AIEC) Infection

Exosomes are abundance in human body fluids like urine, milk and blood. They act a critical role in extracellular and intracellular communication, intracellular trafficking and physiological regulation. Multiple immune-modulatory components, such as proteins, RNAs and carbohydrates (glycoproteins), have been found in human milk exosomes, which play immune-regulatory functions. However, little is known about oligosaccharides in milk exosomes, the “free sugars”, which act critical roles in the development of infant’s immature mucosal immune system. In this study, the profile of milk exosomes encapsulated human milk oligosaccharides (HMOs) was calibrated with characteristic oligosaccharides in colostrum and mature milk, respectively. The exosomes containing human milk oligosaccharides were uptaken by macrophages, which were responsible for the establishment of intestinal immunity. Furthermore, mice pretreated with exosome encapsulated HMOs were protected from AIEC infection and had significantly less LPS-induced inflammation and intestinal damage. Exosome encapsulated milk oligosaccharides are regarded to provide a natural manner for milk oligosaccharides to accomplish their critical functions in modifying newborn innate immunity. The understanding of the interaction between a mother’s breastfeeding and the development of an infant’s mucosal immune system would be advantageous. The transport of milk oligosaccharides to its target via exosome-like particles appears to be promising.

Dirichlet series expansions of p-adic L-functions

We study p-adic L-functions $$L_p(s,\chi )$$ L p ( s , χ ) for Dirichlet characters $$\chi $$ χ . We show that $$L_p(s,\chi )$$ L p ( s , χ ) has a Dirichlet series expansion for each regularization parameter c that is prime to p and the conductor of $$\chi $$ χ . The expansion is proved by transforming a known formula for p-adic L-functions and by controlling the limiting behavior. A finite number of Euler factors can be factored off in a natural manner from the p-adic Dirichlet series. We also provide an alternative proof of the expansion using p-adic measures and give an explicit formula for the values of the regularized Bernoulli distribution. The result is particularly simple for $$c=2$$ c = 2 , where we obtain a Dirichlet series expansion that is similar to the complex case.

Multiple perspectives integration for virtual reality-aided assemblability assessment in complex virtual assembly environment

Virtual Reality (VR) has been proved as a promising tool for industrial design, but the traditional VR interface of first-person perspective (1PP) is not useful enough to support assemblability assessment in complex virtual assembly environments. In this paper, we proposed the multi-perspectives interface (MPI) which integrates the 1PP and the third-person perspective (3PP) using handheld World-in-Miniature (WIM). The MPI allows users to simulate the assembly operations in a natural manner similar to 1PP, while providing users with an overview of the assembly status through the WIM to assess the assemblability with superior spatial awareness. Two studies were included in this paper. The first study tested MPI in a general interaction task, which reveals stronger spatial awareness in MPI than in 1PP without the cost of losing natural interaction. The second study tested the performance, usability, and workload of MPI in an assemblability assessment task. The results show the advantages of MPI in the reachability evaluation. The contribution of this paper is exploring a novel interface for VR-aided assembly design and evaluation system.

Simulating Peptide Monolayer Formation: GnRH-I on Silica

Molecular dynamics (MD) simulations can provide a detailed view of molecule behaviour at an atomic level, which can be useful when attempting to interpret experiments or design new systems. The decapeptide gonadotrophin-releasing hormone I (GnRH-I) is known to control fertility in mammals for both sexes. It was previously shown that inoculation with silica nanoparticles (SiNPs) coated with GnRH-I makes an effective anti-fertility vaccine due to how the peptide adsorbs to the nanoparticle and is presented to the immune system. In this paper, we develop and employ a protocol to simulate the development of a GnRH-I peptide adlayer by allowing peptides to diffuse and adsorb in a staged series of trajectories. The peptides start the simulation in an immobile state in solution above the model silica surface, and are then released sequentially. This facile approach allows the adlayer to develop in a natural manner and appears to be quite versatile. We find that the GnRH-I adlayer tends to be sparse, with electrostatics dominating the interactions. The peptides are collapsed to the surface and are seemingly free to interact with additional solutes, supporting the interpretations of the GNRH-I/SiNP vaccine system.

On the integral transform of Mittag-Leffler-type functions with applications

In this article, we study certain results connected with a generalized Mittag-Leffler function. A generalized Mittag-Leffler function operator of Laplace and Sumudu conversions are investigated and some applications of the recognized results are also deduced as corollaries in this article. The outcomes of the present study are valuable in solving fractional order mathematical models in science, mathematics, finance and technology where the Mittag-Leffler function arises in a natural manner.