Ultra-high-speed multi-parametric photoacoustic microscopy

Multi-parametric photoacoustic microscopy (PAM) is uniquely capable of simultaneous, high-resolution mapping of blood hemoglobin concentration, oxygenation, and flow in vivo. However, its speed has been limited by the dense sampling required for blood flow quantification. To overcome this limitation, we have developed an ultra-high-speed multi-parametric PAM system, which enables simultaneous acquisition of ~500 densely sampled B-scans by superposing the rapid laser scanning across the line-shaped focus of a cylindrically focused ultrasonic transducer over the conventional mechanical scan of the optical-acoustic dual foci. A novel optical-acoustic combiner is designed and implemented to accommodate the short working distance of the transducer, enabling convenient confocal alignment of the dual foci in the reflection mode. This new system enables continuous monitoring of microvascular hemoglobin concentration, blood oxygenation, and flow over a 4.5 x 3 mm2 area in the awake mouse brain with high spatial and temporal resolution (6.9 μm and 0.3 Hz, respectively).

Enabling Extended Reach Wells with the Aid of an Ultra-High Speed Rotational Reamer Shoe

Well X is an infill horizontal well designed for the Gulf of Thailand. It is challenging due to the following factors - A long 8 ½ inch open hole section, An extended reach section at horizontal or near horizontal, the presence of loss circulation zones, an Extended Reach Drilling (ERD) ratio of 2.725 and a Drilling Difficulty Index (DDI) of 6.762. The key challenge was to successfully deploy the 7 inch casing across 12,350 ftMD of open hole, with potential loss circulation zones. In spite of these difficulties, the 7 inch casing was successfully landed with the use of an Ultra-High Speed Rotational Reamer Shoe. Historically, losses of circulation have posed significant challenges to well delivery in the Gulf of Thailand wells. In Well X, this is further complicated by a long open-hole section with a step-out of over 10,000 ftMD. It was determined that the successful deployment of the 7 inch casing would require some degree of agitation at the nose, and such a device must be tolerant to the Lost Circulation Materials (LCM) type and the composition of the drilling fluid and the cement. An ultra-high speed rotational reamer shoe was specially configured to meet the LCM requirements in the displaced fluid, for use in deploying the casing. While deploying the 7 inch casing, losses of up to 20 bbls/hr occurred from 7,043 ftMD while running at 15 joints/hr. A loss circulation recipe comprising of 60 bbls of 30 ppb Tiger LCM was mixed and successfully displaced through the customized ultra-high speed reamer shoe to cure losses. The casing was washed down from 10,569 to 11,610 ftMD, filling casing each stand. The 7 inch casing was successfully landed at the target depth of 12,353 feet and subsequently cemented. Drill out operations took 1.5 hours to complete. A formation integrity test (FIT) showed good shoe strength which was later confirmed by the cement evaluation logs. The comprehensive Ultra-High Speed Reamer Shoe was configured with a minimum restriction of 15mm, which is 5 times the diameter of the maximum particle size in the LCM of 3 mm. The tool was designed to tolerate the prescribed loss circulation materials, making it possible to cure the losses while running the casing string. The innovative Ultra-High Speed Reamer Shoe has demonstrated its usefulness by providing a higher probability for successfully deploying the 7 inch production casing over the extended reach section of Well X. The application of this technology can mitigate against non-productive time such as wiper trips or excessive washing down or casing rotation. It has proven to be a reliable technology that can be used in the industry in challenging well designs.

Horizontal vibration response analysis of ultra-high-speed elevators by considering the effect of wind load on buildings

At present, the wind-induced vibration effects of super-high-rise buildings caused by wind loads can no longer be ignored. The wind-induced vibration effect of super-high-rise buildings will inevitably cause the vibration of ultra-high-speed elevators. However, for the study of the vibration characteristics of ultra-high-speed elevators, the wind-induced vibration effect of the ultra-high-speed elevator is often ignored. Based on Bernoulli–Euler theory, the forced vibration differential equation of elevator guide rail was established, and the vibration equation of elevator guide shoe and car was established by using the Darren Bell principle. The coupled vibration model of the guide rail, guide shoes, and car can be obtained through the relationship of force and relative displacement among these components. Based on the model, the effects of wind pressure and building height on the horizontal vibration of the ultra-high-speed guideway and passenger comfort were analyzed. The results showed that the influence of the wind load on the vibration of ultra-high-speed elevator can no longer be disregarded, and the maximum horizontal vibration acceleration of the guide rail is positively correlated with the height of building. The vibration acceleration of the same height rail increases with the increase in wind pressure. The vibration dose values (VDVs) increase with the increase in wind pressure and building height, respectively.