The effect of fumaric acid, dipromonium and vitamin C on the productivity of sows

The article presents the results of the effect of fumaric acid, dipromonium and vitamin C on productivity, physiological state and natural resistance of sows. The scientific and economic experience was carried out at the pig-breeding complex with a production capacity of 27 thousand heads “Voskhod” in the Mogilev region of Belarus. Forty primiparous gilts were divided into four groups (n = 10): a control and three experimental groups. Experimental gilts received basal diet supplemented with fumaric acid (4.0 g/kg of dry matter), dipromonium (0.4 g/kg) or vitamin C (0.1 g/kg) from 1 to 20 d of lactation. The animals of the control group did not receive the indicated preparation. The use of additives contributed to an increase in the milk yield of pigs, the viability of piglets and their growth rate by 21.1-30.0% (P<0.05), 6.0-6.6 and 10.0-27.9%, respectively, as well as influenced the morphological, biochemical and immunological parameters of the blood of pigs and their progeny.

Milk quality and its technological suitability for processing after the disinfection of the udder teats in cows

Experiments on the study of preclinical evaluation of disinfectants based on chlorhexidine bigluconate hydrochloride / aloe tree oil (CGB aloe) and polyhexamethylene biguanide hydrochloride / eucalyptus oil (Teasfoam Supercow) showed their low hazard when exposed to warm-blooded animals. Disinfectants are assigned to the fourth hazard class according to GOST 12.1.007-76. The concentration of Staph. aureus, Strep. agalactiae was lower when teats were immersed in Teasfoam Supercow disinfectant solution before and after milking, compared to untreated teats. It is concluded that the application of CGB aloe is very efficient against Staph. aureus, Strep. Agalactiae, E. coli and Strep. uberis. Based on the results of scientific and economic experience, it can be concluded that controlled disinfection of the udder teats with a disinfectant CGB aloe before and after milking cows with high milk yield does not prevent udder teat hyperkeratosis in 2.4% of animals. In addition, subclinical mastitis is diagnosed in 12.1%; 3.3% of cows during the disinfection of the udder teats with Teasfoam Supercow were diagnosed hyperkeratosis of the udder teats. Another 12.9% of animals had subclinical mastitis. Udder teats of control animals were not disinfected. Udder hyperkeratosis was diagnosed in 5.4% of cows. Another 26.5% of the animals fell ill with subclinical mastitis. In cows, after controlled disinfection of the udder teats, an increase in milk production by 1-2 liters was observed. No color, taste or odor changes were observed in the milk. It has been proven that teats disinfection reduces the number of bacteria on the teats skin, improves the sanitary milk quality and its manufacturability.

Navigating the high costs of cancer care: opportunities for patient engagement

Over the past decade, the financial burden of cancer care on patients and their families has garnered increased attention. Many of the potential solutions have focused on system-level interventions such as adopting value-based payment models and negotiating drug prices; less consideration has been given to actions at the patient level to address cancer care costs. We argue that it is imperative to develop and support patient-level strategies that engage patients and consider their preferences, values and individual circumstances. Opportunities to meet these aims and improve the economic experience of patients in oncology are discussed, including: shared decision-making and communication, financial navigation and treatment planning, digital technology and alternative care pathways, and value-based insurance design.

Increasing the efficiency of calves rearing in the post-daily period

Aim. To establish the effect of raising young cattle on whole milk, a substitute for whole and skimmed milk powder on its productivity and physiological state in the post-dairy period. Materials and Methods. The studies were conducted on three groups of young cattle of the first phase of cultivation, 10 heads each, at the age of 115 days with an initial live weight of 125.3-127.5 kg. Animals of all groups were given the same diet. During the dairy period, the calves of the control group received milk, a second and third substitute for whole milk and a substitute for skimmed milk powder. Classical and modern zootechnical, biochemical and mathematical methods of analysis were used in research. The digital material obtained in the course of the research was processed by the method of variation statistics, taking into account the Student's criterion of reliability and using the Microsoft Excel software package. Results. Taking into account the feed consumption in the scientific and economic experience showed that the consumption of silage-haylage mixture increased by 0.5-0.6 kg in the animals of the experimental groups. 1 kg of dry matter contained 10.47-10.56 MJ of exchange energy and 0.90-0.91 feed units, 13.4% of crude protein and 22.4-23.2% of fiber. Per 1 feed unit, 95.7-96.4 g of digestible protein was accounted for. As a result of the research, it was found that the majority of the blood parameters studied by us, reflecting the general physiological state of the body, in the compared groups were within the physiological norm. In the blood of animals of the II and III experimental groups, compared with control animals, there was an increase in the number of red blood cells by 10.0 and 9.8%, hemoglobin – by 5.8 and 3.9%, glucose – by 11.0 and 9.5%. The study of the growth dynamics of experimental animals during the experimental period of scientific and economic experience showed that the increase in the live weight of young animals of the experimental group was more intense than the control ones. At the same time, the average daily increase in live weight of control calves was 796.7 g, experimental calves-870.0 and 881.7 g, or increased by 9.2 and 10.7%. The increase in the growth energy of the bulls of the experimental group allowed to obtain an additional 4.4 and 5.1 kg of live weight per head during the experiment period. Based on the conducted studies, it was found that the cost of feed per kg of growth in the II and III experimental groups was lower than the control variant by 5.8 and 7.6%, and therefore the cost of growth in the experimental groups decreased by 6.1 and 7.7% compared to the control analogues, this allowed us to get additional profit per 1 head in the experimental groups in the amount of 8.35 and 10.58 rubles for the research period. Conclusion. The use of ZTSM and ZSOM in feeding young cattle at the age of 10-115 days provided an increase in the average daily increase in the post – dairy period by 9.2 and 10.7%, while reducing the cost of feed for obtaining an increase by 5.8 and 7.6%, the cost of growth-by 6.1 and 7.7 percent.

VETERINARY AND SANITARY EXAMINATION OF YAROK MEAT WHEN USING UVMC «VITA BALANCE»

The purpose of the study was to study the effect of UVMC "Vita Balance" on the quality in-dicators of veterinary and sanitary examination of Yarok meat, in the conditions of scientific and economic experience. To do this, two groups of bright spots were selected using the method of ana-log pairs-an experimental group and a control group. Animals of the experimental group were given free rein for 45 days to lick the UVMC "Vita Balance". Research on veterinary and sanitary exami-nation of yark meat was conducted in the laboratory of veterinary and sanitary examination of the Kazan gavm. Analysis of the obtained results confirmed that when using the new feed additive UVMC "Vita Balance" in feeding yarkas, the daily need for the actual feeding ration in the conditions of this farm was 25.5±1.6 g per day per head. The results of veterinary and sanitary examination of yark meat by organoleptic, physico-chemical and bacteriological indicators of yark meat of control and experimental groups are fresh and had no distinctive features.

Evaluation of meat productivity of Holstein bull calves in conditions of the Lower Volga Region

Aim. To study the influence of linear affiliation on the meat productivity of Holstein gobies. Materials and Methods. The experimental part of the work was carried out in 2019-2020 on the territory of a dairy unit for milk production, “Donskoe” farm enterprise, LLC, Kalachevsky district, the Volgograd region. For the experiment, 3 groups of 10 heads were formed according to the principle of analogues of purebred Holstein bulls from three lines: Reflection Sovering, Vis Back Ideal, and Montvik Chieftain. During the scientific and economic experiment, the technology of keeping animals used in beef cattle breeding was used. Classical and modern zootechnical methods are used in the process of research. The obtained research materials were processed by the method of variation statistics, taking into account the reliability criterion according to the Student, using the Microsoft Excel software package. Results. Studies have established that in order to achieve the desired parameters of the live weight gain of bull calves, it is necessary to drink them with whole milk. During 2.5 months, the experimental animals consumed 198 liters of whole milk per head. To obtain high average daily gains in fat mass from the 6th day of life, starter feed and finely crushed grain were introduced into the diet of steers. The norms of nutrients were determined depending on the planned growth and live weight. The results of changes in absolute indicators of live weight of calves with age showed that calves belonging to the line of Reflection Sovering 198998, with intensive cultivation, grow much faster than their peers from other lines. The results of the control slaughter show that at the age of 13 months, it is possible to obtain sufficiently full-bodied carcasses from animals. The largest carcass weight was observed in the Reflection Sovering 198998 bull calves (240.5 kg), which is 7.7 and 19.1 kg or 3.2 and 8.2% more than in the peers from other groups. When deboning carcasses, it was found that the bulls of the Reflection Sovering 198998 line also exceeded the pulp mass by 4.0 and 14.9 kg or 2.04 and 7.59% (P ≥ 0.99), and the pulp yield by 0.7 and 0.8%. Thus, it is established that the belonging of bull calves to different lines is related to the change in the composition of the carcass, the ratio between muscle, bone and adipose tissue. Conclusion. Scientific and economic experience shows that high indicators of meat productivity can be obtained from German-bred Holstein steers of various linear varieties, which can serve as a necessary reserve for increasing the level of beef production.

Effectiveness of a probiotic based on lactic acid bacteria when changing diets in dairy cows

Relevance. Single-type feeding of dairy cows has a significant advantage over traditional split ration feeding due to the minimal frequency of changes in the composition of the ration and the higher stability of feeding. However, in the process of such a feeding method, it is still necessary to change the diet composition during the seasonal transition from the last year feed to the current year feed. This change leads to significant feed stress for animals, which negatively affects the intensity and nature of cicatricial digestion, and, consequently , productivity. At the same time, at least 100-150 kg of the annual milk yield of a cow is lost. For this reason, the development of a method for eliminating the inevitable cows' stress during the change of feeding seems relevant.Methodology. Scientific and economic experience on dairy cows of the first lactation phase was carried out in accordance with generally accepted methods. The biochemical composition of the blood was studied, observations of the ruminatory processes were carried out, the data were processed by modern methods of variation statistics using the EXCEL program.Results. As a result, it was found that during the transition from one diet composition to another, it is advisable to introduce a probiotic based on lactic acid bacteria into dairy cows diet. The use of a probiotic can be considered as a preventive measure for digestive disorders caused by changes in the composition of the diet. The use of a probiotic helps to stabilize the ruminal processes in cows, which is reflected in an increase in the frequency of cicatricial contractions. Probiotic effect on the intestinal microbial community, increases the immune status of the body by increasing the level of protein, gamma-globulin fractions in its composition, as well as increasing the reserve alkalinity index.