scholarly journals Enhancement of dynamic range and complete elimination of self-interference artifacts in a spectral domain OCT: Potential for high performance at much lowered-cost

2021 ◽  
Vol 5 ◽  
pp. 100144
Author(s):  
Denny Melkay M. George ◽  
Hari Nandakumar ◽  
Shailesh Srivastava
Author(s):  
Sergey Pisetskiy ◽  
Mehrdad Kermani

This paper presents an improved design, complete analysis, and prototype development of high torque-to-mass ratio Magneto-Rheological (MR) clutches. The proposed MR clutches are intended as the main actuation mechanism of a robotic manipulator with five degrees of freedom. Multiple steps to increase the toque-to-mass ratio of the clutch are evaluated and implemented in one design. First, we focus on the Hall sensors’ configuration. Our proposed MR clutches feature embedded Hall sensors for the indirect torque measurement. A new arrangement of the sensors with no effect on the magnetic reluctance of the clutch is presented. Second, we improve the magnetization of the MR clutch. We utilize a new hybrid design that features a combination of an electromagnetic coil and a permanent magnet for improved torque-to-mass ratio. Third, the gap size reduction in the hybrid MR clutch is introduced and the effect of such reduction on maximum torque and the dynamic range of MR clutch is investigated. Finally, the design for a pair of MR clutches with a shared magnetic core for antagonistic actuation of the robot joint is presented and experimentally validated. The details of each approach are discussed and the results of the finite element analysis are used to highlight the required engineering steps and to demonstrate the improvements achieved. Using the proposed design, several prototypes of the MR clutch with various torque capacities ranging from 15 to 200 N·m are developed, assembled, and tested. The experimental results demonstrate the performance of the proposed design and validate the accuracy of the analysis used for the development.


Sensors ◽  
2021 ◽  
Vol 21 (15) ◽  
pp. 5164
Author(s):  
Jacob Compaleo ◽  
Inder J. Gupta

Recently, we proposed a Spectral Domain Sparse Representation (SDSR) approach for the direction-of-arrival estimation of signals incident to an antenna array. In the approach, sparse representation is applied to the conventional Bartlett spectra obtained from snapshots of the signals received by the antenna array to increase the direction-of-arrival (DOA) estimation resolution and accuracy. The conventional Bartlett spectra has limited dynamic range, meaning that one may not be able to identify the presence of weak signals in the presence of strong signals. This is because, in the conventional Bartlett spectra, uniform weighting (window) is applied to signals received by various antenna elements. Apodization can be used in the generation of Bartlett spectra to increase the dynamic range of the spectra. In Apodization, more than one window function is used to generate different portions of the spectra. In this paper, we extend the SDSR approach to include Bartlett spectra obtained with Apodization and to evaluate the performance of the extended SDSR approach. We compare its performance with a two-step SDSR approach and with an approach where Bartlett spectra is obtained using a low sidelobe window function. We show that an Apodization Bartlett-based SDSR approach leads to better performance with just single-step processing.


2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Pierre-Maxime Lévêque ◽  
Pierre Zéboulon ◽  
Emmanuelle Brasnu ◽  
Christophe Baudouin ◽  
Antoine Labbé

Purpose. To detect changes in optic nerve head (ONH) vascularization in glaucoma patients using spectral-domain OCT angiography (OCT-A).Material and Method. Fifty glaucoma patients and 30 normal subjects were evaluated with OCT-A (AngioVue®, Optovue). The total ONH vessel density and temporal disc vessel density were measured. Clinical data, visual field (VF) parameters, and spectral-domain OCT evaluation (RNFL: retinal nerve fiber layer thickness, GCC: ganglion cell complex thickness, and rim area) were recorded for glaucoma patients. Correlations among total and temporal ONH vessel density and structural and VF parameters were analyzed.Results. In the glaucoma group, total and temporal ONH vessel density were reduced by 24.7% (0.412 versus 0.547;p<0.0001) and 22.88% (0.364 versus 0.472;p=0.001), respectively, as compared with the control group. Univariate analysis showed significant correlation between rim area (mm2) and temporal ONH vessel density (r=0.623;p<0.0001) and total ONH vessel density (r=0.609;p<0.0001). Significant correlations were found between temporal and total ONH vessel density and RNFL, GCC, VF mean deviation, and visual field index.Conclusion. In glaucoma patients OCT-A might detect reduced ONH blood vessel density that is associated with structural and functional glaucomatous damage. OCT-A might become a useful tool for the evaluation of ONH microcirculation changes in glaucoma.


2011 ◽  
Vol 383-390 ◽  
pp. 471-475
Author(s):  
Yong Bin Hong ◽  
Cheng Fa Xu ◽  
Mei Guo Gao ◽  
Li Zhi Zhao

A radar signal processing system characterizing high instantaneous dynamic range and low system latency is designed based on a specifically developed signal processing platform. Instantaneous dynamic range loss is a critical problem when digital signal processing is performed on fixed-point FPGAs. In this paper, the problem is well resolved by increasing the wordlength according to signal-to-noise ratio (SNR) gain of the algorithms through the data path. The distinctive software structure featuring parallel pipelined processing and “data flow drive” reduces the system latency to one coherent processing interval (CPI), which significantly improves the maximum tracking angular velocity of the monopulse tracking radar. Additionally, some important electronic counter-countermeasures (ECCM) are incorporated into this signal processing system.


Robotica ◽  
1996 ◽  
Vol 14 (3) ◽  
pp. 321-327 ◽  
Author(s):  
R.E. Ellis ◽  
O.M. Ismaeil ◽  
M.G. Lipsett

SUMMARYA haptic interface is a computer-controlled mechanism designed to detect motion of a human operator without impeding that motion, and to feed back forces from a teleoperated robot or virtual environment. Design of such a device is not trivial, because of the many conflicting constraints the designer must face.As part of our research into haptics, we have developed a prototype planar mechanism. It has low apparent mass and damping, high structural stiffness, high force bandwidth, high force dynamic range, and an absence of mechanical singularities within its workspace. We present an analysis of the human-operator and mechanical constraints that apply to any such device, and propose methods for the evaluation of haptic interfaces. Our evaluation criteria are derived from the original task analysis, and are a first step towards a replicable methodology for comparing the performance of different devices.


2022 ◽  
Vol 145 ◽  
pp. 107492
Author(s):  
P. Hlubina ◽  
M. Gryga ◽  
D. Ciprian ◽  
P. Pokorny ◽  
L. Gembalova ◽  
...  

Sensors ◽  
2018 ◽  
Vol 18 (10) ◽  
pp. 3370 ◽  
Author(s):  
Saghi Forouhi ◽  
Rasoul Dehghani ◽  
Ebrahim Ghafar-Zadeh

This paper proposes a novel charge-based Complementary Metal Oxide Semiconductor (CMOS) capacitive sensor for life science applications. Charge-based capacitance measurement (CBCM) has significantly attracted the attention of researchers for the design and implementation of high-precision CMOS capacitive biosensors. A conventional core-CBCM capacitive sensor consists of a capacitance-to-voltage converter (CVC), followed by a voltage-to-digital converter. In spite of their high accuracy and low complexity, their input dynamic range (IDR) limits the advantages of core-CBCM capacitive sensors for most biological applications, including cellular monitoring. In this paper, after a brief review of core-CBCM capacitive sensors, we address this challenge by proposing a new current-mode core-CBCM design. In this design, we combine CBCM and current-controlled oscillator (CCO) structures to improve the IDR of the capacitive readout circuit. Using a 0.18 μm CMOS process, we demonstrate and discuss the Cadence simulation results to demonstrate the high performance of the proposed circuitry. Based on these results, the proposed circuit offers an IDR ranging from 873 aF to 70 fF with a resolution of about 10 aF. This CMOS capacitive sensor with such a wide IDR can be employed for monitoring cellular and molecular activities that are suitable for biological research and clinical purposes.


2013 ◽  
Vol 54 (11) ◽  
pp. 1748
Author(s):  
Geun Yeong Kim ◽  
You Kyung Lee ◽  
Jung Il Moon ◽  
Myoung Hee Park

1999 ◽  
Vol 82 (6) ◽  
pp. 1308-1315 ◽  
Author(s):  
Francisco García Sánchez ◽  
Aurora Navas Díaz ◽  
Angeles García Pareja ◽  
Germán Cabrera Montiel

Abstract High-performance liquid chromatography using a combination of photometric, fluorimetric, and diode-laser polarimetric detectors in series for the determination of (+)-quinidine and (–)-quinine was investigated. An RP-8 reversed-phase column and methanol-water (80 + 20, v/v) with 0.2% triethylamine as mobile phase at a flow rate of 1 mL/min were used. A dynamic range of 0-200 μg for (+)-quinidine and (+)-quinine was established, with detection limits of 17.0 and 16.7 μg, respectively. An application of this method in spiked rabbit serum was developed.


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