Grasses one of the largest families of higher plants, including about 12000 species from 950 genera. The paper presents up-to-date information about the taxonomic composition, geographical distribution and habitat conditions of cereals in the South of the Middle Volga region (within the Penza, Samara and Ulyanovsk regions). studies of Grasses were conducted throughout the southern Middle Volga region, and herbarium collections stored in LE, MOSP, MW, PKM, PVB, etc. were also studied. Agrostology the South of the Middle Volga region are 72 genera (including 2 nothogenera) and 221 species (including 5 nothospecies). In the flora of the Southern Middle Volga region, 20 rare species of Grasses, of which 5 species are included in the Red book of the Russian Federation (2008): Koeleria sclerophylla, Stipa dasyphylla, S. pennata, S. pulcherrima, S. zalesskii; 14 species – in the Red book of the Penza region (2013): Drymochloa sylvatica, Festuca wolgensis, Helictotrichon desertorum, Melica transsilvanica, Scolochloa festucacea, Stipa borysthenica, S. dasyphylla, S. lessingiana, S. pennata, S. pulcherrima, S. sareptana, S. tirsa, S. zalesskii, Trisetum sibiricum; 18 species – in the Red book of the Samara region (2017): Avenula pubescens, Bromopsis benekenii, Catabrosella humilis, Cinna latifolia, Cleistogenes squarrosa, Drymochloa sylvatica, Elytrigia pruinifera, Helictotrichon schellianum, Koeleria sclerophylla, Pholiurus pannonicus, Poa saksonovii, Psathyrostachys juncea, Stipa dasyphylla, S. korshinskyi, S. pennata, S. pulcherrima, S. tirsa, S. zalesskii; 18 species – in the Red book of the Ulyanovsk region (2015): Catabrosella humilis, Cleistogenes squarrosa, Drymochloa sylvatica, Festuca cretacea, F. wolgensis, Helictotrichon desertorum, Koeleria sclerophylla, Leymus ramosus, Nardus stricta, Psathyrostachys juncea, Stipa borysthenica, S. dasyphylla, S. korshinskyi, S. lessingiana, S. pennata, S. pulcherrima, S. tirsa, S. zalesskii. Only Poa saksonovii is endemic to the South of the Middle Volga region; 5 types of Grasses are described from the study area: Festuca wolgensis, Koeleria sclerophylla, K. transvolgensis, Leymus paboanus, Poa saksonovii.