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Author(s):  
Ivan Bobul

The purpose of the article is to study the artistic and aesthetic features of vocal and pop art as a genre synthesis of arts. The research methodology involves the use of system-structural, comparative methods of analysis and culturological and art approaches in the study of these issues. The scientific novelty of the work is to expand the theoretical boundaries of understanding vocal and pop performance as a synthetic genre that combines different arts, and its defining artistic and stylistic features that directly affect the structure and stylistic features of vocals, interpretation of the work, its perception by listeners and representation of values, ideas and impressions generated in the process of performance and its perception. Conclusions. Conclusions. Variety vocal performance as a kind of musical text involves special manifestations of intertextuality, so it is possible to find layers of artistic and species series, expressive forms and meanings, artistic and linguistic means and interpretive techniques. From the point of view of specific tasks of artistic communication, it appears as a generalized form of musical and artistic activity that can claim universality and has its stage and staging canons, determined by value concepts of culture, but in their new popular sense. There are also exemplary compositional and semantic models in this field, the imitation of which is a recognized way to join the pop vocal and performing professionalism. In the field of pop and vocal performance in its theatrical and staged form there is a specific mythologizing, which concerns the figure of the singer as the central actor of the concert program, which forms a certain image to achieve extreme artistic persuasiveness. Therefore, it is not an image of a fictional character, but of a person close in time and meaning to life, as she can and should be in virtual artistic reality - aesthetically sublime and morally balanced. The main components of the intertextual sphere, which is formed around the variety show and determines the special director's interest in it, are semantic positions on the singer as a semantic core of the whole moving picture of pop and stage action. It is these semantic factors that organize and lead to a holistic artistic result all the structural indicators of pop performance. Keywords: vocal and pop art, artistic and aesthetic characteristics, genre specifics, genre synthesis of arts.


2021 ◽  
Vol 34 (1) ◽  
Author(s):  
Frederico Monteiro Neves ◽  
Guineverre Alvarez ◽  
Fábio Fernandes Corrêa ◽  
João Batista Lopes Silva

The region that comprises the Atlantic Forest is one of the most degraded areas of the planet, being especially vulnerable in climate change scenarios, which project a mean temperature increase between 2ºC and 3ºC by 2070 for the Brazilian Northeast region. This article aims to analyze the main drivers of socio-environmental vulnerability in the Atlantic Forest region that comprises the southernmost identity territory of Bahia (Brazil) and their potential consequences for coping with climate change. To this end, historical data on land use and occupation was spatialized and evaluated, along with socioeconomic indicators and legal environmental adequacy in the municipalities that make up this territory. The results indicate four structural drivers that generate regional vulnerabilities: the persistence of deforestation; the continuous expansion of monoculture areas; the maintenance of low levels of well-being of the population; as well as a picture of legal environmental liabilities. Based on the analysis of these data, strategies are proposed to increase the adaptive capacity to climate change in this region, especially considering the role of municipalities as a central actor in the implementation of adaptation actions by incorporating into their existing planning instruments indicators and strategies that address the multiple current challenges, especially when the federal government seems to be neglecting climate change.


Author(s):  
Jan Eijking

Abstract The French political theorist Henri de Saint-Simon is largely absent from historical International Relations (IR). This article shows why this is unwarranted and introduces him as an international thinker who made lasting contributions to IR's modern conceptual imagination. Largely responding to the French Revolution Saint-Simon rethought the parameters of international order, imagining the international as a realm separable from national politics and conformable to human agency. International order, on his account, could be actively created. This could take the shape of legislation, trade, or large-scale engineering projects: of new methods of governance. Based on a close reading of texts rarely brought into IR’s focus, this article introduces Saint-Simon as a thinker who cut across traditional IR divides and developed a central actor category of international order: impartial, knowledge-based agents of change. His understanding of international reform not only made it possible to theorize and experiment with a role in global governance for technical experts but also masked the imperial underpinnings of the international projects these experts facilitated. The article makes the case that Saint-Simon deserves a firm place in historical IR, that his thought presents an opportunity for revisiting widely held assumptions about international authority, and that a discernible Saint-Simonian strand of international thought puts typically liberal histories of global governance in question.


2021 ◽  
Author(s):  
Alberto Blanch Jover ◽  
Nicola De Franceschi ◽  
Daphna Fenel ◽  
Winfried Weissenhorn ◽  
Cees Dekker

AbstractThe Cdv proteins constitute the cell-division system of the Crenarchaea, in a protein machinery that is closely related to the ESCRT system of eukaryotes. The CdvB paralog CdvB1 is believed to play a major role in the constricting ring that is the central actor in cell division in the crenarchaea. Here, we present an in vitro study of purified CdvB1 from the crenarchaeon M. sedula with a combination of TEM imaging and biochemical assays. We show that CdvB1 self-assembles into filamentous polymers that are depolymerized by the action of the Vps4-homolog ATPase CdvC. Using liposome flotation assays, we show that CdvB1 binds to negatively charged lipid membranes and can be detached from the membrane by the action of CdvC. Interestingly, we find that the polymerization and the membrane binding are mutually exclusive properties of the protein. Our findings provide novel insight into one of the main components of the archaeal cell division machinery.


2021 ◽  
Vol 8 ◽  
Author(s):  
Vladimir L. Cousin ◽  
Raphael Giraud ◽  
Karim Bendjelid

Angiotensin converting enzyme 2 (ACE2) seems to be a central actor in the pathophysiology of SARS-Cov-2 infection. First, it acts as the receptor for the virus and permits its attachment to cells expressing ACE2. Second, the relative deficiency of ACE2 during infection could be linked to several clinical features encountered during the disease, like ARDS and coagulation abnormalities. This study explores the strong link between ACE2 and the majority of risk factors for the severe evolution of COVID-19. It seems that all these risks factors are linked to an increased level of ACE2 and/or imbalance in ACE/ACE2.


Terminology ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 80-109
Author(s):  
Nina Pilke ◽  
Niina Nissilä ◽  
Hans Landqvist

Abstract The present study deals with organised terminology work in Sweden from the 1940s to the late 2010s. Using archive material, we describe how practical terminology work was carried out in Sweden during the period 1941–2018/2019, when the Swedish Centre for Technical Terminology/the Swedish Centre for Terminology (TNC) was the central actor. Thereafter, we discuss models for building a new infrastructure for terminology work after the closure of the TNC in 2018/2019. This discussion is based on interviews and analyses of articles and current reports. The study shows that multifaceted contacts with experts, academia, industry and society have played an essential role for terminology work in Sweden since the 1930s. In the current situation (2019), the activities are being reorganised and responsibility for terminology work is distributed between several actors. A new main actor is the government agency known as the Institute of Language and Folklore (Isof). Finally, we discuss future visions for terminology work in Sweden.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Taisson Toigo ◽  
Douglas Wegner ◽  
Silvio B. da Silva ◽  
Felipe de Mattos Zarpelon

Purpose This study aims to present a theoretical analysis on the capabilities (at the organizational) and skills (at the individual level) of the hub organization (orchestrator) in an innovation network. Design/methodology/approach The authors conducted literature reviews on the orchestration of innovation networks; and networking capabilities. Findings This study presents a theoretical model and a research agenda. Originality/value In interorganizational relations, a central actor can stand out the role of intentionally creating, extracting and distributing value in the network, generating gains for all members. Literature recognizes this set of intentional and deliberate actions as the “orchestration” of resources in the network. Despite the increasing interest regarding the theme, the phases and specific capabilities for orchestration still lack further investigation.


Author(s):  
Martin Mennecke

Abstract It is a commonplace in the R2P discourse to describe accountability measures as key means to implement the responsibility to protect. In particular, the International Criminal Court is regularly highlighted as a central actor, both in the literature, the annual R2P reports issued by the UN Secretary-General, and the subsequent debates in the UN General Assembly. Conspicuously absent from this conversation is the principal judicial organ of the United Nations, the International Court of Justice (icj). This article examines the potential role of the ‘World Court’, as The Gambia in November 2019 started a new case under the UN Genocide Convention against Myanmar before the icj. Analysing the limitations and prospects and existing icj case-law, the article concludes that the International Court of Justice can make an important and unique contribution to the responsibility to protect.


2021 ◽  
Vol 22 (8) ◽  
pp. 4134
Author(s):  
Sayma Zahid ◽  
Murielle Seif El Dahan ◽  
Florence Iehl ◽  
Paloma Fernandez-Varela ◽  
Marie-Helene Le Du ◽  
...  

DNA double-strand breaks (DSBs) are accidental lesions generated by various endogenous or exogenous stresses. DSBs are also genetically programmed events during the V(D)J recombination process, meiosis, or other genome rearrangements, and they are intentionally generated to kill cancer during chemo- and radiotherapy. Most DSBs are processed in mammalian cells by the classical nonhomologous end-joining (c-NHEJ) pathway. Understanding the molecular basis of c-NHEJ has major outcomes in several fields, including radiobiology, cancer therapy, immune disease, and genome editing. The heterodimer Ku70/80 (Ku) is a central actor of the c-NHEJ as it rapidly recognizes broken DNA ends in the cell and protects them from nuclease activity. It subsequently recruits many c-NHEJ effectors, including nucleases, polymerases, and the DNA ligase 4 complex. Beyond its DNA repair function, Ku is also involved in several other DNA metabolism processes. Here, we review the structural and functional data on the DNA and RNA recognition properties of Ku implicated in DNA repair and in telomeres maintenance.


2021 ◽  
pp. 369-384
Author(s):  
Joseph P. McCormick II ◽  
Todd C. Shaw ◽  
Robert A. Brown

In this volume, we have presented a conceptual framework that argues the American constitutional order has entailed various racial orders that advanced either more racially exclusive or more racially inclusive policy agendas. The American presidency has been a central actor in these orders. One key conclusion we reach based on the analyses of our contributors is that the historic presidency of Barack Obama attempted to advance the policy interests of various African American communities across several dimensions—e.g., voting rights, criminal justice reform, healthcare, and housing. And while African American communities may have had what we call an “inverted linked fate” with Obama (or linked their sense of well-being with Obama’s perceived political well-being), Obama’s personal linked fate with African American communities—i.e., Black women, Black LGBTQ persons, faith-based communities, etc.—did not overcome what we call the “inclusionary dilemma.” Despite African American voters being critical to Obama’s electoral victories, the aforementioned orders imposed constraints upon the Obama policy agenda and fueled the president’s reluctance to press more left-of-center policy prescriptions that would be of greater benefit to Black communities. We end by considering the Obama administration’s shortfalls relative to a new, progressive Black politics during the Trump administration.


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