Development and evaluation of lead(II) iodide-based polycrystalline digital dosimeter for quality assurance in brachytherapy

Brachytherapy is a cancer treatment that involves intensively irradiating a tumor by placing a sealed radioactive isotope inside the body. Determining the position of the source through accurate quality assurance (QA) is important, because brachytherapy uses radioactive isotope sources with high dose rates. However, in clinical practice, the source position is determined with the naked eye through the use of a ruler, autoradiograph, video monitor, etc., which yields inaccurate results. Therefore, in this study, a lead (II) iodide (PbI2) based polycrystalline digital dosimeter that can measure the relative dose was developed for the QA of the brachytherapy device, and its applicability was evaluated in terms of reproducibility, linearity, percentage interval distance (PID), and angular dependence. Reproducibility evaluation yielded a relative standard deviation value of 1.41%, which satisfied the evaluation criterion of 1.5%. The linearity evaluation yielded an R2 value of 0.9993, which satisfied the evaluation criterion of 0.9990. The PID evaluation revealed that, as the distance from the source increased, the signal decreased according to the inverse-square law. When the PbI2-based digital dosimeter was rotated up to 45°, a difference of up to 13.20% in the angular dependence was observed. Thus, the dosimeter fabricated in this experiment met all the criteria of the aforementioned evaluations. Therefore, it is considered to be highly applicable as a dosimeter for the QA of brachytherapy devices.

Performance evaluation of lead-monoxide dosimeter with parylene coating for quality assurance of brachytherapy devices

The source position of irradiation is identified using a method that uses rulers and films for quality assurance (QA) in brachytherapy. However, this method involves a high probability of errors, because the scales are checked using the naked eye, and QA is indirectly performed using photographs. Lead monoxide (PbO) is widely used as a semiconductor dosimeter, because it is a photoconductor that generates electrons in response to electromagnetic waves. Moreover, PbO has excellent sensitivity to reflected rays, owing to its high atomic number (Z Pb: 82, Z O: 8) and density (ρPbO: 9.53 g/cm3). We applied PbO to a dosimeter for QA in a brachytherapy device and attempted to increase the signal stability with a parylene coating for performance improvement. Subsequently, a comparative analysis was performed with a PbO dosimeter that was not coated with parylene to determine whether the fabricated dosimeter is applicable as a dosimeter for QA of the brachytherapy device, by analyzing the reproducibility, linearity, percentage interval distance (PID), and angular dependence in the 192Ir source used for brachytherapy. The RSD of the non-parylene PbO dosimeter was 0.85%, and the RSD of the parylene PbO dosimeter was 0.40% in the reproducibility results. In the linearity evaluation results, the R 2 value of the non-parylene PbO dosimeter was 0.9996, and that of the parylene PbO dosimeter was 0.9997 In the PID evaluation results, the difference in the intensity distribution measured according to the distance due to the dose was attenuated at the coated parylene in the case of the parylene PbO dosimeter. Therefore, adjustments using correction coefficients are required for suitable performance. In the angular dependence evaluation results, the parylene PbO dosimeter had 3.44% less angular dependence than the non-parylene dosimeter at an angle of 45°. The parylene-coated PbO dosimeter showed better performance than the non-parylene-coated PbO dosimeter in terms of the reproducibility, linearity, and angular dependence. Therefore, it is considered that the parylene-coated PbO dosimeter can be implemented for QA of brachytherapy devices.

An Experiment-Based Simplified Method for the Model of Building Groups in CFD Simulation

Computational Fluid Dynamics (CFD) has been widely used in the simulation and analysis of community or urban wind environments. However, the CFD-based wind simulation of large-scale building groups usually consumes a lot of computing resources with high computing costs. To improve the efficiency of CFD-based wind simulation, this paper presents an experiment-based simplified method for the model of building groups. Two rectangular buildings are adopted as the basic unit and four control parameters (B/L, W/L, H/L, and D/L) are selected as the experiment factors to analyze the geometrical relationship of the two buildings. Note that L, W, and H, respectively, represent the windward edge length, width, and height of a building, B is building interval distance, and D is the distance between two building center axes. Then, a single factor experiment and an orthogonal experiment are designed and performed to determine the reasonable value range of each factor. Based on the experiment results and actual situation, the value ranges of four factors for the simplification of building group models are determined as follows: B/L∈{0, 1.5}, W/L∈{0, 2}, D/L∈{0, 0.25}, and H/L∈{0, 1}. Furthermore, a real case is presented to evaluate the performance of the proposed simplified method. The results indicate that the simplified method is able to improve the efficiency of CFD-based wind simulation of building groups, with the number of buildings decreasing from 620 to 395 (by 36.3%), and the number of tetrahedral grids decreasing from 8,832,199 to 7,766,778 (by 12.1%). Thus, this research contributes to the CFD-based wind simulation method of large-scale building groups and the analysis of the urban wind environment.

Computational fluid dynamics modelling of quasi-collimated beam apparatus – a typical bench scale UV apparatus for water treatment

Quasi-collimated beam apparatus (QCBA), a typical bench scale UV apparatus, is crucial for the biodosimetry determination of UV dose in target reactors. However, the key parameters for the QCBA construction are usually estimated via rule-of-thumb calculations. Computational fluid dynamics models are applied in this study to simulate the UV fluence rate (FR) distributions in QCBAs. QCBAs with either a cylindrical tube or successive apertures irradiate quasi parallel light into selected dishes. The simulated Petri factor (PF) in the target QCBAs with a single aperture were all >0.84, and increased with the extended distance (L1) from the UV lamp to the upper aperture. QCBAs with two successive apertures are recommended compared with those with three apertures or cylindrical tube. A trend of FR distribution from dispersed to concentrated is observed when L1 or the interval distance between each aperture increases in a dual-aperture QCBA. QCBAs with multiple lamps were favorable to increase the UV output power, while having a nearly negligible loss of parallelism. An actual QCBA was constructed, and the maximal and average FR, and PF values in a 60-mm dish were 0.159 and 0.164 W/m2, and 0.967, respectively, in accordance with the simulated results.

An Innovative Elastoplastic Analysis for Soft Surrounding Rock considering Supporting Opportunity Based on Drucker-Prager Strength Criterion

In order to study the mechanism of excavation and supporting process of equivalent circular roadway, the model of soft roadway was established firstly. The elastoplastic solutions in excavation process were deduced based on Drucker-Prager strength criterion. Then, the elastoplastic solution under supporting condition was obtained based on homogenization method under the condition of rockbolts and liner supporting. Lastly, an example was analyzed to study the effect of different factors such as “space effect,” supporting opportunity, stresses, surrounding displacement, and the radius of plastic zone. Based on theoretical research case, the change rules of considering the “space effect” and the supporting opportunity when calculating the subarea of the roadway were discussed, the control of interval distance of rockbolts on the displacement of surrounding rock mainly reflecting in the plastic residual zone and the “space effect” in excavation, and the supporting time to control the displacement of surrounding rock not being ignored are revealed. The results can provide an important theoretical basis for the stability evaluation and quantitative support design of roadway surrounding rock. Therefore, the “space effect” and the supporting time to control the displacement and stresses of surrounding rock can not being ignored in underground engineering.

Priority Measurement of Patches for Program Repair Based on Semantic Distance

Automated program repair is an effective way to ensure software quality and improve software development efficiency. At present, there are many methods and tools of automated program reapir in real world, but most of them have low repair accuracy, resulting in a large number of incorrect patches in the generated patches. To solve this problem, we propose a patch quality evaluation method based on semantic distance, which measures the semantic distance of patches by using features of interval distance, output coverage, and path matching. For each evaluation feature, we give a quantitative formula to obtain a specific distance value and use the distance to calculate the recommended patch value to measure the quality of the patch. Our quality evaluation method evaluated 279 patches from previous program repair tools, including Nopol, DynaMoth, ACS, jGenProg, and CapGen. This quality evaluation method successfully arranged the correct patches before the plausible but incorrect patches, and it recommended the higher-ranked patches to users first. On this basis, we compared our evaluation method with the existing evaluation methods and judged the evaluation ability of each feature. We showed that our proposed patch quality evaluation method can improve the repair accuracy of repair tools.

Stiffness and Distance of Lateral Support Member Considering Buckling Strength of Sliding Track Panel

Recently, the concept of a Sliding Track Panel (STP) system, which allows the bridge to slide in the longitudinal direction, has been proposed for continuous welded rail method laid on long span non-ballast bridges, such as truss railway bridges. The performance of the STP system is determined based on the ability to prevent the lateral buckling of STP. This study attempts to derive the optimum interval distance and required stiffness of the lateral support member to be installed in the STP system through buckling analysis. According to the analysis, the interval distance of lateral support member, which satisfies the strength of STP, is less than 2.8 m and the rigidity is more than 800 N/mm.

Using the Interval Metric for Modeling Entities Geometrics in R2 – Case Study Interval Circumference

The study of some distances provide science away to separate two entities.It has applications in various fields such as remote sensing, datamining, pattern recognition and multivariate data analysis and others. If the distance is a Hausdorff metric, the guarantee is that all individuals are available. With the use of the distance of Trindade et al, we intend to extend the real topology to an interval topology, since the interval distance preserves the uncertainties and exits noise in the data. The present work proposes an interval circumference using an interval distance of a point to the center (pixel), like a set of pixels obeying certain distances to the center. With the interval circumference we intend to extend the notion of open ball and the concepts of neighborhood for the construction of the interval topology. A circumference separates a space into three regions, inner region, border region and outer region, where we construct our notion of neighborhood. In this work we will explore only the geometric properties of the intervalcircumference, we will extrapolate the notion from point to pixel by providing a differentiated frontier region for the clustering area.