SPECIFITY AND EFFICIENCY OF COMPUTER MONITORING OF KNOWLEDGE AS A HIGHPRIORITY METHOD OF DIAGNOSIS OF THE LEVEL OF STUDENTS’ ACADEMIC ACHIEVEMENTS

Research issues of specificity and efficiency of the computer monitoring of knowledge as a high-priority method of diagnostics of the level of students’ educational attainments are made actual. The essence of the interrelated notions such as “ computer monitoring of knowledge”, “ computer testing”, “ test assignment” is revealed.On the basis of analysis of available references the objective of computer testing is defined, the reasons of figuring out the objective results which are achieved by the means of two constituents that are proper prepared test and actionable hardware system are set. At the same time the general properties of test such as validity, complexity, reliability, stability, representativeness, significancy, truthfulness, test hypothesis and discriminant are assigned. As a rule, test consists of two parts: informational and operational. The technology of constructing test tasks is characterized, it presupposes observance of number of rules: each test task should evaluate the achievements of an important and significant educational goal; it should check the appropriate level of knowledge acquisition, as well as higher cognitive levels and the time allocated for the test task which should be spent on finding the answer, but not on understanding the condition of the question. Along with that, the efficiency of computer testing is analyzed, which depends on the variability and multiplicity of created test tasks. Based on the results of the research we have the reason to confirm that computer testing being promising direction of modern educational process becomes constituent of the modern knowledge diagnostics. It broadens the means of control and evaluation of the level of educational achievements, it is an alternative to traditional methods of monitoring, it can be carried out taking into account different types and forms of control as a tool of operational management.Computer testing enables to audit knowledge of a large number of people simultaneously in a short span of time; random selection of questions from the course unit; processing of test results on a personal computer using a rating scale.

Results of use of polyacrylamide gel Noltrexsin in patients with different grades of gonarthrosis in outpatient practice

Introduction. Osteoarthritis of the knee joints is the most common joint disease affecting more than 80% of people over 55 years of age. The priority method for the treatment of gonarthrosis is the use of local injection therapy with the introduction of synovial fluid endoprostheses based on hyaluronic acid, included in the Second Step of the ESCEO 2019 algorithm. Viscoelastic polyacrylamide gels for intra-articular administration since 2003 have also shown their high effciency in the symptomatic OA treatment. Since 2018, the new 3rd generation PAAG endoprosthesis of synovial fluid, Noltrexsin, has been actively used.Objective. To compare the efficacy and safety of Noltrexsin viscoprosthesis use with oral NSAIDs in patients with grade I-III of gonarthrosis.Materials and methods. 40 patients with gonarthrosis participated in a comparative study of the effcacy and safety of injection therapy Noltrexsin 4.0 ml No. 2 (study group, А) and oral administration of NSAIDs 200 mg per day (comparison group, В). NSAIDs were taken in groups A and B, the duration of therapy in both groups was 1 month. The results were evaluated by standard examination methods, including measuring the range of motion in the joint and scoring of physical signs, tests with walking up the stairs and at a distance, VAS, WOMAC, Lequesne Index.Results. In group А, a more signifcant reduction in pain according to VAS was revealed to 15–20 mm at the grade I–II of gonarthrosis and up to 25–30 mm in the grade III, a decrease in the Lequesne index to 1–2 and 3–4 points, respectively. In group В with a standard therapy, and then on-demand within 6 months, a decrease in VAS was revealed on the 8–9th day, and after 6 months the level of pain at the grade I–II did not exceed 20–25 mm, at the grade 3 it did not decrease below 40–45 mm. The Lequesne Index decreased to 2 points at the grade I–II and to 6–7 points at the grade III. Changes of WOMAC index correlated with VAS.Conclusions. 1. Noltrexsin can be used as a safe endoprosthesis of synovial fluid in the form of local injection therapy in patients with insufficient effect of chondroprotectors and NSAIDs. 2. Noltrexsin is recommended for use at all stages of arthrosis, as well as in comorbid patients.

Device for fusion drilling with simultaneous or follow-up reaming of wells in ice

The paper deals with a new opening technology for subglacial reservoirs, which ensures environmentally friendly geological exploration. The technology is based on the results of the first openings of the subglacial Lake Vostok in Antarctica (February 2012 and January 2015). The primary goal of further studies of the subglacial Lake Vostok is to take clean samples of lake water and bottom sediments, which requires direct penetration into the lake. There is a number of conditions to be met in order to conduct further studies of the lake using a clean access well at the Vostok drilling complex. The article summarizes the main results including technological and engineering solutions protected by the patent of the Russian Federation. A detailed consideration is given to a new device for fusion drilling with simultaneous reaming of an ice hole. This device combines two technological processes: drilling due to contact melting, and an increase in the diameter of the well due to the creation of a vortex flow of a continuously heated coolant in the bottomhole zone. The thermal method of ice breaking ensures the ecological cleanliness when opening subglacial reservoirs and is a priority method that favorably differs from the existing ones. The device was named a “thermal drill reamer” (TDR). During the seasonal work of the 64th Russian Antarctic Expedition bench tests of the TDR 132/400 were carried out, the results of which confirmed that the device is capable to ensure 132 mm drilling with simultaneous reaming up to 400 mm.

Survival analysis of the femoral component retained in isolated acetabular revision of the hip prosthesis

Introduction Isolated acetabular revision with the retention of a well-fixed and aligned femoral component is the priority treatment method in aseptic acetabular loosening. The aim of the research was to predict the survival rate of a well-fixed and aligned femoral component retained during the isolated acetabular revision surgery. Material and methods We used the survival tables and the Kaplan-Meier method to create the survival curves. The object of the study was the database of 44 patients (45 interventions) who underwent isolated acetabular revision surgeries with their well-fixed and aligned femoral components that was retained. The average age of the patients was 59.5 [50; 69.5] years. The ratio of women to men was 25:19, respectively. The observation period was 1374 days. The creation of tables and graphs was carried out in Statistica 13.3 software package. Results The survival rate of the retained well-fixed and aligned femoral component in isolated acetabular revision within the period up to 4 years was high and amounted to 0.9524 ± 0.03. The probability density and the hazard rates were 0.0017 and 0.00320, respectively. Discussion The retention of a well-fixed and aligned stem in acetabular revision features high survival of the components as well as a low risk of endoprosthesis failure within 3 to 4 years. This fact confirms the need to maintain a stable and correctly oriented stem to reduce the surgical trauma, obtain good functional results and reduce rehabilitation terms. Conclusion Isolated acetabular revision in isolated aseptic cup loosening is a priority method of surgical treatment with a low risk of complications in the postoperative period.

Recommendations for the conservation of the wild onions (Allium) gene pool in the Northwestern Federal District of Russia

Relevance. Preservation of the plant genetic diversity is necessary for carrying out largescale breeding activities in order to improve existing economically important species and create varieties of cultivated plants. The priority method is the in situ conservation. Hence is the relevance of studies of vulnerable crop wild relatives (CWR) in the Northwestern Federal District of Russia (NWFDR) for designing recommendations on their in situ conservation.Materials. The materials used in the present work were the herbarium collections of the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (WIR), of the V.L. Komarov Botanical Institute of the Russian Academy of Sciences (LE), as well as the literature data, results of expeditionary surveys by VIR in 1946, 1948 and 1949, and from 2005 to 2020. The species included in the regional Red Data Books (RDB) were analyzed, data from GBIF and CWR open databases, and materials and maps of the Agroatlas used.Results and Discussions. Six species of the genus Allium, i.e. A. angulosum L., A. oleraceum L., A. schoenoprasum L., A. strictum Schrad., A. vineale L., and A. ursinum L. have been identified and proposed for conservation in the Northwestern Federal District of Russia. Maps have been built, numerous data sources, as well as the author’s own observations, analyzed. Conservation recommendations have been developed for each species based on their vulnerability.

Lactoferrin: properties and application. A review

The current state, prospects for using and priorities in studying multifunctional protein lactoferrin (LF) in the food industry are discussed. Over the last decades, the studies of iron-binding, antibacterial, antiviral and antiparasitic properties of this representative of transferrins have determined quite a wide sphere of its use. The data on the lactoferrin composition, structure and activity are presented. The authors describe the modern methods for lactoferrin extraction and production from dairy raw materials both in the domestic and foreign productions using chromatographic methods for extraction and membrane methods for production. The practical experience in its application for food production, in particular, for meat and fermented dairy products, child and sports nutrition is discussed. An effect of technological process parameters in food production on the LF activity is highlighted. The study analyses an influence of new processing technologies such as high pressure or pulsed electric field in combination with classic methods for thermal processing and drying on the structure and activity of lactoferrin in food. The reviewed studies show that the use of lactoferrin in the meat industry, especially, in finished meat products, has limitations. The data presented in the review suggest a need for searching ways of lactoferrin introduction into meat systems to obtain functional products. One of the top-priority method for LF incorporation into meat products is LF encapsulation as one of the production stages.

Results of Treatment of Patients with Ureterolithiasis by Extracorporal Shock Wave Lithotripsy on Siemens Modularis Uro

Extracorporeal shock wave lithotripsy (ESWL) has been used in the treatment of urolithiasis since 1980s. The method has proven to be effective and minimally invasive, but in last years the effectiveness of the method has decreased significantly from 90 % to 60 %. Studying of the causes of this phenomenon and methods of improving treatment outcomes are important problems of modern minimally invasive urology. The objective: to evaluate the effectiveness of the application of ESWL on Siemens Modularis Uro in the treatment of patients with ureterolithiasis. Materials and methods. ESWL was performed in 662 patients with ureteral stones ranging in size from 5 mm to 19 mm on Siemens Modularis Uro. Results. In 95.01 % of cases, the urinary tract was free of stones by the method of ESWL, the removal of stones in 1 session occurred in 376 (56.8 %) patients, with repeated – in 253 (43.2 %) patients. In 33 (4.99 %) patients the result of ESWL was unsatisfactory, fragmentation or elimination of stone fragments did not occur and for these patients ureteroscopy (ureterolithotripsy) was performed as second stage of treatment. During endoscopic intervention in 78.8 % of patients the fragmentation was satisfactory (fragments were smaller than 4 mm), but the elimination of fragments did not occur due to changes of the wall of the ureter in the area of its primary location. The overall rate of stone fragmentation after ESWL sessions in the patients in the trial was 98.94 %. Conducting ESWL with the proposed parameters did not affect the effectiveness of the method (p>0.1), but allowed to significantly increase the life of medical equipment. No complications directly related to lithotripsy were detected. Conclusion. The obtained results make possible to consider ESWL as a priority method of treatment for patients with ureteral stones up to 15 mm, taking into account the risk factors of inefficiency.

CHANGING OF CULTURAL IDEA OF TEACHING FOREIGN LANGUAGES IN THE 30S OF XX CENTURY

Рассматривается процесс изменения вектора государственной политики в сфере изучения иностранного языка в 30-е годы ХХ века. Показано, что после революции 1917 г. изучение иностранного языка было прекращено, потому что расценивалось как пережиток прошлого, антагонистического общества с ярко выраженным и непримиримым классовым неравенством. Однако в 1923 г. Н. К. Крупская в статье «О преподавании иностранных языков» доказательно опровергла необходимость изучения эсперанто и четко обосновала свою позицию по поводу изучения иностранных языков, описала практическую значимость, обозначила основную цель и показала приоритетный метод их преподавания, заложив тем самым основы изучения иностранных языков в нашей стране на многие десятилетия. Рассматривается ряд постановлений Центрального комитета Коммунистической партии Советского Союза от 1929 и 1932 гг., направленных на усиление изучения иностранного языка в городских школах второй ступени, техникумах и вузах, фабрично-заводских семилетках. Приводятся размышления общественных и политических деятелей, педагогов, публицистов, филологов о культурологическом потенциале иностранных языков. Показана цель их изучения в 30-е годы ХХ века. The article deals with the process of changing the vector of state policy in the field of foreign language learning in the 30s of the XX century After the October Revolution, they stopped the study of a foreign language because they regarded it as a relic of the past, an antagonistic society with a pronounced and irreconcilable class inequality. However, in 1923, Nadezhda Konstantinovna Krupskaya denied the need to study Esperanto on a national scale in her article “Teaching Foreign Languages” and described the practical significance, main goal and priority method of teaching a foreign language and more than that her own position about the role of foreign languages, thereby laying the foundation for its study for many decades. The 1927 became a further important step in the history of teaching a foreign language in the country of the Soviets. The People’s Commissariat for Education of the RSFSR adopted a special decree on the study of a foreign language in all city schools of the second level, starting a large campaign “Foreign languages to the masses”. It considers a number of resolutions of the Central Committee of the Communist Party of the Soviet Union from 1929 and 1932, aimed at strengthening the study of a foreign language in all city schools, technical schools and universities, and Factory Seven-Years. The article gives the reflections of public and political figures, teachers, publicists, philologists on the cultural potential of foreign languages. It shows the purpose of foreign language study in the 30s of the XX century.

LEGAL REGULATION OF THE USE OF ELECTRONIC SIGNATURES IN ELECTRONIC COMMERCE

The article is devoted to the legal problems of using documents signed with electronic signatures in electronic commerce. The article considers the different legal regime of electronic documents depending on the type of electronic signature. Legal features of a qualified electronic signature are analyzed. The legal status of a certification service provider and its legal functions in e-commerce are examined. The conclusion is made about the recognition of electronic documents as a priority method of legal interaction in the field of electronic commerce and the complication of the legal construction of an electronic signature.