Short term stratospheric ozone trend over Dumdum and its relation with Flare Index of northern hemisphere

This paper presents an analysis of the effect of flare index (Q) on the stratospheric ozone concentration over Dumdum station, Kolkata for the period 1979-95. As Dumdum is situated in northern hemisphere we have considered the flare index values for the northern hemisphere only.

Carrington Longitudinal and Solar Cycle Distribution of the Super Active Regions From 1976 to 2018

We studied the Carrington longitudinal and solar cycle distribution of the super active regions (SARs) from 1976to 2018. There were 51 SARs during this period. We divided the SARs into SARs1 and SARs2. SARs1 refers tothe SARs that produced extreme space weather events including ≥X5.0 flares, ground level events (GLEs) andsuper geomagnetic storms (SGSs: Dst≤ −250 nT), while SARs2 did not produce extreme space weather events.The total number of SARs1 and SARs2 are 32 and 19, respectively. The statistical results show that 34.4%, 65.6%and 78.1% of the SARs1 appeared in the ascending phase, descending phase and in the period from two yearsbefore to the three years after the solar maximum, respectively, while 52.6%, 47.4% and 100% of the SARs2appeared in the ascending phase, descending phase and in the period from two years before to the three years aftersolar maximum, respectively. The Carrington longitude distribution of the SARs1 shows that SARs1 in thelongitudinal scope of [0,150°] produced ≥X5.0 flares and GLEs, while only the SARs1 in the longitude range of[150°,360°] not only produced ≥X5.0 flares and GLEs, but also produced SGSs. The total number of SARsduring a SC has a good correlation with the SC size. However, the largest flare index of a SAR within a SC has apoor correlation with the SC size, implying that the number of SARs in a weak SC will be small. However, aweak SC may have a SAR that can produce very strong solar flare activities.

Impact of teleconsultation on subsequent disease activity and flares in patients with systemic lupus erythematosus

Objectives Despite the widespread adoption of teleconsultations amid the COVID-19 pandemic, their safety in SLE patients has not been evaluated. Here, we examined subsequent disease activity and flares among SLE patients who received teleconsultation vs in-person consultation. To discern differences in physicians’ prescription behaviour during both forms of consultations, we compared corticosteroid dose adjustments. Methods We studied adult SLE patients who were seen between 1 February 2020 and 1 February 2021. At each patient-visit, rheumatologists utilized phone/video teleconsultation or physical consultation at their discretion. Disease activity was assessed with SLE Disease Activity Index 2000 (SLEDAI-2K) and flares were defined by the SELENA-SLEDAI Flare Index (SFI). We derived a propensity score for patients who were chosen for physical consultation. Multivariable generalized estimation equations were used to analyse SLEDAI-2k and flare at the next visit, adjusted for the propensity score. Results A total of 435 visits were recorded, of which 343 (78.9%) were physical visits and 92 (21.1%) were teleconsultations. The modality of consultation did not predict flare [OR for physical consultation (95% CI) 0.42 (0.04, 5.04), P =0.49] or SLEDAI-2k at the next visit [estimate of coefficient for physical consultation (95% CI) −0.19 (−0.80, 0.43), P =0.55]. Adjustments of prednisolone dosages were comparable between the two forms of visits [OR for physical consultation (95% CI) 1.34 (0.77, 2.34), P =0.30]. Conclusion SLE disease activity and flares at the subsequent visit were similar between teleconsultations and physical consultations. Medication prescription behaviour, determined using adjustment in corticosteroid dosages, was not different between the two forms of visits.

Periodic Variation of Solar Flare Index for the Last Solar Cycle (Cycle 24)

In this study, we used the flare index (FI) data taken from Kandilli Observatory for the period of 2009–2020. The data sets are analyzed in three categories as Northern Hemisphere, Southern Hemisphere, and total FI data sets. Total FI data set is obtained from the sum of Northern and Southern Hemispheric values. In this study, the periodic variations of abovementioned three categories FI data sets were investigated by using the MTM and Morlet wavelet analysis methods. The wavelet coherence (XWT) and cross wavelet (WTC) analysis methods were also performed between these data sets. As a result of our analysis, the following results were found: (1) long- and short-term periodicities ( 2048 ± 512 day and periodicities smaller than 62 days) exist in all data sets without any exception at least with 95 % confidence level; (2) all periodic variations were detected maximum during the solar cycle, while during the minima, no meaningful period is detected; (3) some periodicities have data preference that about 150 days Rieger period appears only in the whole data set and 682-, 204-, and 76.6-day periods appear only in the Northern Hemisphere data sets; (4) During the Solar Cycle 24, more flare activity is seen at the Southern Hemisphere, so the whole disk data periodicities are dominated by this hemisphere; (5) in general, there is a phase mixing between Northern and Southern Hemisphere FI data, except about 1024-day periodicity, and the best phase coherency is obtained between the Southern Hemisphere and total flare index data sets; (6) in case of the Northern and Southern Hemisphere FI data sets, there is no significant correlation between two continuous wavelet transforms, but the strongest correlation is obtained for the total FI and Southern Hemisphere data sets.

Comparison of radiographic and tomographic evaluations for measurement of the Canal Flare Index in dogs

ABSTRACT The outcome of total hip arthroplasty (THA) in dogs is directly related to surgical planning. Templating of radiographs prior to THA should help the surgeon anticipate prosthesis size and femoral shape allowing canal fill of the proximal metaphysis by the implant ensuring primary stable fixation. The canal flare index (CFI) obtained from radiograph has been used as a measure of risk of complications for the technique in human beings and dogs. However, standard radiographs only provide limited data for the selection of cementless prostheses and the assessment of their fit within the femoral canal, due to factors like radiographic magnification and femoral rotation. Therefore, three-dimensional evaluation based on computed tomography (CT) may be a better tool for CFI measurement. The aim of this study was to compare anatomical measurement with CFI values obtained from craniocaudal radiography and CT. Craniocaudal radiographs using a horizontal radiographic beam (CR), CT, and anatomical macroscopic measurements (A) were obtained from 45 femurs from 23 canine cadavers. The differences between the values of CFI obtained from radiograph (CFI-R), computed tomography on transverse (CFI- TT) and longitudinal axis (CFI-TL) compared to the CFI obtained from macroscopic measurements - gold standard - (CFI-A), and 95% limits of agreement (LOA) between the values, were evaluated by the Bland-Altman method. Dimensions obtained from CT techniques had a greatest mean difference from anatomical and CFI values were also different (P=0.032). Under the experimental conditions, the craniocaudal radiograph, provided the most accurate measurement of the CFI (mean difference: 0.087 ± 0.42).

Which patients with systemic lupus erythematosus in remission can withdraw low dose steroids? Results from a single inception cohort study

Background A progressive tapering until withdrawal of glucocorticoids (GC) is considered one of the main goals of Systemic Lupus Erythematosus (SLE) management. However, which patient may be a candidate for safe GC withdrawal has not been determined yet. This study aimed to evaluate the rate of low-dose GC withdrawal in SLE patients in remission and to identify predictors of flares. Methods Eligible patients were SLE patients in prolonged clinical remission defined by a cSLEDAI = 0 for at least 2 years and on a stable SLE treatment (including daily 5 mg prednisone). Flares were defined by SELENA-SLEDAI Flare Index. Predictors of flares after GC withdrawal were analyzed by Cox regression. Results We selected 56 patients in whom a GC withdrawal was attempted. 98 patients were in the prednisone maintenance group. The proportion of patients experiencing a flare was not significantly lower in the maintenance group than in the withdrawal group (p = 0.81). However, among the withdrawal group, the rate of flares was significantly higher in serologically active clinically quiescent (SACQ) patients (p < 0,0001). At Cox regression analysis, duration of hydroxychloroquine (HCQ) therapy and ≥5 year remission at withdrawal were protective factors, while a SACQ disease and history of lupus nephritis increased the risk of disease flare. Conclusion GC withdrawal is an achievable target in SLE and may be attempted in patients in complete remission.However, it might underline a caution in patients with SACQ disease who may be at greater risk forflare when GCare discontinued. HCQ therapy and durable remission can significantly reduce the risk.

Canal flare index evaluation for different dog breeds

ABSTRACT: This study determined the canal flare index (CFI) of four dog breeds using two distinct femoral regions as a reference. Thirty-five radiographs of the hip joints of Golden Retrievers (GRG), German Shepherds (GSG), Labrador Retrievers (LRG), and Rottweilers (RG) of both sexes were used. Seventy experimental units were submitted to CFI calculation. Objective (CFIob) and subjective (CFIsub) values of the CFI of each experimental unit were determined according to the anatomical reference used for the calculation. A significant difference in the CFIob between the Golden Retriever and German Shepherd breeds (1.68 ± 0.16 and 1.49 ± 0.08), and in the CFIsub between Golden Retriever, German Shepherd, and Rottweiler breeds (2.09 ± 0.31, 1.86 ± 0.11, and 1.84 ± 0.18) was reported. The subjective form of measurement showed higher values than the objective form (GRG: 2.09 ± 0.31; GSG: 1.86 ± 0.11; LRG: 2.07 ± 0.12; RG: 1.84 ± 0.18). The CFI values of each breed were similar, suggesting a certain racial pattern. A significant difference in the interobserver assessment for both CFIsub and CFIob, in all races was observed. The CFI analysis identified morphological patterns of the proximal femur in the different races. Results indicated the need for standardization of the anatomical references used to calculate the CFI because there were statistical differences among the measurements among the observers.