SAMARA CITY UNDERGROUND URBANIZATION DEVELOPMENT AND ITS CONSEQUENCES

Nowadays the area of cities is almost everywhere increasing - the territory urbanization is developing. At the same time, due to lack of land resources, the underground space development intensifi es, and the underground construction volume increases, i.e., underground urbanization takes place. This process has undoubtedly positive results, as it can help solve territorial, transport, environmental and other problems of cities while preserving the unique appearance of buildings in the historical centers of cities. At the same time, some engineering and geological processes may be activated as a negative underground urbanization result. The article deals with underground urbanization history in Samara and defi nes its main stages. More than one million people live in Samara city, subway line was built, there are subway objects of industrial and defense importance (bunkers) reaching considerable depth. Active underground construction can lead to geological processes strengthening (weathering, karst formation, suff osia, etc.), change of strength properties of rocks, violation of natural hydrological regime of the territory. The territory of Samara has an inhomogeneous geological structure and complex engineering and geological construction conditions. Seven engineering-geological districts have been identifi ed and studied, on the territory where underground construction development can lead to diff erent, including negative, consequences.

Does the Western-Ghats play any dynamical role in the distance effect of vortex over the Bay of Bengal on the enhancement of monsoon rainfall over Pune?

lkj & bl ’kks/k i= esa nf{k.k&if’pe ekulwu _rq ¼,l-MCY;w-,e-,l-½ ds nkSjku caxky dh [kkM++h esa mBs coaMj ds nwjorhZ izHkko ds QyLo:Ik iq.ks esa o"kkZ esa gqbZ o`f) esa if’peh ?kkV ¼MCY;w-th-½ dh xR;kRed Hkwfedk ¼;fn dksbZ gks rks½ dh tk¡p djus dk iz;kl fd;k x;k gSA bldh tk¡p djus ds fy, e/; ekiØe vojks/k ds Åij ok;q&izokg ds ,d xR;kRed ekWMy dk mi;ksx fd;k x;k gSA N% ?kVukvksa ds v/;;u ls ;g Kkr gqvk gS fd caxky dh [kkM+h esa coaMj mBus dh fLFkfr esa iq.ks esa gqbZ o"kkZ esa o`f) ns[kh xbZ gSA bu N% ?kVukvksa esa ls pkj ?kVukvksa esa ;g ns[kk x;k gS fd xR;kRed ekWMy iq.ks esa o"kkZ dh izsf{kr ?kV&c<+ ¼deh&cs’kh½ dk irk yxkus esa xq.kkRed :Ik ls lQy jgk gSA bu pkjksa ?kVukvksa esa if’peh iousa if’pe rV ds fdukjs m/okZ/kj esa vis{kkÑr dkQh rhoz FkhaA vU; nks ?kVukvksa esa ls ,d ?kVuk esa ;g ekWMy o"kkZ dh vf/kdrk dks] de ls de xq.kkRed :Ik esa] irk yxkus esa lQy jgk gS ijUrq o"kkZ esa deh dk irk yxkus esa vlQy jgk gSA ,d vU; ?kVuk esa ;g ekWMy iq.ks esa o"kkZ dh ?kV&c<+ Kkr djus esa xq.kkRed :Ik ls Hkh iw.kZr;k vlQy jgk gSA vafre nks ?kVukvksa esa if’pe rVh; LVs’ku ij if’peh iou detksj ,oa lrgh FkhA An attempt has been made to examine the dynamical role (if any) played by the Western Ghats (WG), in the distance effect of vortex over the Bay of Bengal (BOB) on the rainfall enhancement over Pune, during southwest monsoon season (SWMS). To examine it, a dynamical model of airflow over a meso-scale barrier has been used. Six cases have been studied, in which enhancement of rainfall over Pune in presence of vortex over the Head Bay are noticed. Out of these six cases, in four cases it is found that the dynamical model can capture, at least qualitatively, the observed fluctuation (rise and fall) of rainfall over Pune. In these four cases westerly along west coast was strong with considerable depth in vertical. In one of the other two cases, the model has been able to capture, at least qualitatively, the observed rise in rainfall but failed to capture the observed fall in rainfall. In the other case the model has failed completely to capture, even qualitatively, the fluctuation in observed rainfall over Pune. In the last two cases, westerly along west coast station was weak and shallow.

Syntheses and Characterization of the First Cycloheptatrienyl Transition-Metal Complexes with a M-CF3 Bond

The organometallic chemistry of metal complexes with organocyclic ligands of higher than five hapticity is much more lacking than the chemistry of metal complexes with η5-cyclopentadienyl ligands, which has been explored in considerable depth, resulting in novel advances. The main reason for this is stability. In particular, reports indicate that (η7-C7H7)MLn complexes are considerably less stable than analogous (η5-C5H5)MLn. In perfluoroalkyl metal chemistry, there is currently no reported (η7-C7H7)MLn derivative, whereas a number of alkylated ones are known and important conclusions have been drawn about their stability. Responding to this void, and using Morrison’s trifluoromethylating reagent, the present study reports the synthesis and characterization of the first cycloheptatrienyl molybdenum complexes bearing the trifluoromethyl moiety; (η7-C7H7)Mo(CO)2CF3 (I), and (η7-C7H7)Mo(CO)(PMe3)CF3 (II) and discusses their low thermal instability.

The Limbal Niche and Regenerative Strategies

The protective function and transparency provided by the corneal epithelium are dependent on and maintained by the regenerative capacity of limbal epithelial stem cells (LESCs). These LESCs are supported by the limbal niche, a specialized microenvironment consisting of cellular and non-cellular components. Disruption of the limbal niche, primarily from injuries or inflammatory processes, can negatively impact the regenerative ability of LESCs. Limbal stem cell deficiency (LSCD) directly hampers the regenerative ability of the corneal epithelium and allows the conjunctival epithelium to invade the cornea, which results in severe visual impairment. Treatment involves restoring the LESC population and functionality; however, few clinically practiced therapies currently exist. This review outlines the current understanding of the limbal niche, its pathology and the emerging approaches targeted at restoring the limbal niche. Most emerging approaches are in developmental phases but show promise for treating LSCD and accelerating corneal regeneration. Specifically, we examine cell-based therapies, bio-active extracellular matrices and soluble factor therapies in considerable depth.

The Prohibited (Haram)

Almost every aspect of halal is essentially concerned with what is the opposite of halal, namely the haram. Hence, haram is treated in considerable depth and in several sections that deal with the types and grounds of haram, such as manifest harm, filth, intoxication, and unlawful acquisition. Haram may be defined as “all that which the Lawgiver (al-shariʿ) has prohibited in definitive terms, and its perpetrator is liable to a punishment in this world or the Hereafter.” It is thus a binding demand from the Lawgiver in respect of abandoning something, and it is conveyed in a variety of linguistic expressions, as the chapter elaborates.

Management of Intracanal Separated File Fragment in a Four-Rooted Mandibular Third Molar

The success of endodontic therapy is attributed to complete arbitration of the bound entities concealed within the complexity and absolute disinfection of the root canal system, thus, deeming it mandatory to effectively negotiate and overcome the challenges posed by obstruction, either iatrogenic or anatomic. To achieve this, considerable depth of knowledge and expertise with reference to variations in root canal morphology and clinical mishap management is substantially as important as developing fine observation skills in conjunction with an appropriate armamentarium and a keen sense of determination, thereby enhancing one’s clinical acumen by several folds. In the present case, following rubber dam isolation, the temporary restoration was removed, and the remaining carious dentin was excavated. Endodontic access cavity was refined and explored with a DG-16 probe, following which three separate canal orifices were identified in the pulp chamber floor (mesiobuccal, mesiolingual, and distal). On further observation under a surgical operating microscope and continuous exploration with the DG-16 probe, a fourth canal was found in the mesial aspect of the tooth (middle mesial). With instrumentation, it was confirmed that a fractured object was indeed present at the apical third of the mesiolingual root of tooth 38. Bypassing of the fractured fragment was initiated with a size 10 SS K-file coupled with copious irrigation with 3% sodium hypochlorite. In the present case report, four distinct canals comprising 3 mesial and 1 distal canal were recognized, and the fractured instrument in one of the canals was bypassed successfully.

The Aegean

Aegeanists rather than Egyptologists have investigated Bronze Age Egypto-Aegean relations. Although a few Egyptologists consider these issues in considerable depth, a general lack of communication still exists between the disciplines. Two issues dominate research and debate: cross-cultural chronology and dating, and consideration of the imported goods and tangible/intangible influence of one civilization upon the other. Less controversial is the issue of contact routes and means, with visible remains and intangible cultural norms. This chapter concerns only Egypt and the Aegean, but they cannot be isolated from developments throughout the East Mediterranean world. All median cultures (and others interacting with them) must also be considered in any discussion. This chapter concentrates mostly on developments since 1990, when Bernal’s Black Athena volumes and the ensuing reaction undoubtedly re-stimulated interest in the subject.

Against the Death Penalty

In 1764, a Milanese aristocrat named Cesare Beccaria created a sensation when he published On Crimes and Punishments. At its centre is a rejection of the death penalty as excessive, unnecessary, and pointless. Beccaria is deservedly regarded as the founding father of modern criminal law reform, yet he was not the first to argue for the abolition of the death penalty. This book presents the first English translation of the Florentine aristocrat Giuseppe Pelli's critique of capital punishment, written three years before Beccaria's treatise, but lost for more than two centuries in the Pelli family archives. The book examines the contrasting arguments of the two abolitionists, who drew from different intellectual traditions. Pelli was a devout Catholic influenced by the writings of natural jurists such as Hugo Grotius, whereas Beccaria was inspired by the French Enlightenment philosophers. While Beccaria attacked the criminal justice system as a whole, Pelli focused on the death penalty, composing a critique of considerable depth and sophistication. The book explores how Beccaria's alternative penalty of forced labour, and its conceptualisation as servitude, were embraced in Britain and America, and delves into Pelli's voluminous diaries, shedding light on Pelli's intellectual development and painting a vivid portrait of an Enlightenment man of letters and of conscience. With translations of letters exchanged by the two abolitionists and selections from Beccaria's writings, the book provides new insights into eighteenth-century debates about capital punishment and offers vital historical perspectives on one of the most pressing questions of our own time.

Endocytosis and the internalization of pathogenic organisms: focus on phosphoinositides

Despite their comparatively low abundance in biological membranes, phosphoinositides are key to the regulation of a diverse array of signaling pathways and direct membrane traffic. The role of phosphoinositides in the initiation and progression of endocytic pathways has been studied in considerable depth. Recent advances have revealed that distinct phosphoinositide species feature prominently in clathrin-dependent and -independent endocytosis as well as in phagocytosis and macropinocytosis. Moreover, a variety of intracellular and cell-associated pathogens have developed strategies to commandeer host cell phosphoinositide metabolism to gain entry and/or metabolic advantage, thereby promoting their survival and proliferation. Here, we briefly survey the current knowledge on the involvement of phosphoinositides in endocytosis, phagocytosis, and macropinocytosis and highlight several examples of molecular mimicry employed by pathogens to either “hitch a ride” on endocytic pathways endogenous to the host or create an entry path of their own.

The UFO Encyclopedia: The Phenomena from the Beginning (3rd ed., 2 vol.) by Jerome Clark

With more than 1500 pages, this is a massive undertaking by SSE Dinsdale Award winner, Jerry Clark. This two-volume third edition is buttressed by his decades of research in the field of UFOs. For this encyclopedic effort he is supported by several competent researchers with international reputations. Typically, my reviews of written works by SSE members tend to be quite favorable as I recognize the difficulty of getting our research into print. This work definitely left me conflicted in an attempt to be both fair to the authors and to the potential readers. In general, the material that is included does provide considerable depth to the cases selected for presentation. As this is the third edition, much of that material has been previously published. Clark and his colleagues have in-depth knowledge of many of the earlier cases and these are well represented. What I found most troubling were some glaring omissions that are hard to reconcile with an encyclopedia that suggests it is comprehensive in nature, as opposed to a representation of cases as selected by the chief editor. Absent is the more recent incidences and evidence that have dramatically altered the entire field of UFOlogy. Given the rapid pace of advancement of knowledge, especially since December 2017, it would be nearly impossible for any print medium to keep pace. Here I am addressing the remarkable revelations by the U.S. Department of Defense concerning interactions between military aircraft and unknown objects. Internally these were so significant as to cause the U.S. Navy to publicly publish a policy position acknowledging these events were occurring frequently. However, it is more than the events of just the past two years that are omitted or downplayed. As a prime example, Phil Corso is not mentioned. In 1997, U.S. Army Lt. Col. Corso’s book The Day After Roswell became an international phenomenon. It dominated much of the conversation in the field. Whether one agrees with Corso or not is irrelevant. His book sold more than any other UFO publication by a great margin and he had significant impact on the field. Thus, both Corso and his book should deserve serious consideration.