Epigenetic Modulation of Vasopressin Expression in Health and Disease

Vasopressin is a ubiquitous molecule playing an important role in a wide range of physiological processes thereby implicated in the pathomechanism of many disorders. Its effect is well characterized through V2 receptors, which regulates the water resorption in kidney, while its vasoconstrictory effect through V1a receptor also received a lot of attention in the maintenance of blood pressure during shock. However, the most striking is its central effect both through the V1b receptors in stress-axis regulation as well as through V1a receptors regulating many aspects of our behavior (e.g., social behavior, learning and memory). Vasopressin has been implicated in the development of depression, due to its connection with chronic stress, as well as schizophrenia because of its involvement in social interactions and memory processes. Epigenetic changes may also play a role in the development of these disorders. The possible mechanism includes DNA methylation, histone modification and/or micro RNAs, and these possible regulations will be in the focus of our present review.

Study on novel structure of Mn complex, C24H18CrMnN4O5

The novel Mn complex C24H18CrMnN4O5 was investigated by hydrothermal and its crystal structure was characterized using X-ray diffraction technology. The Mn atom is six coordinated by four N atom from two 1, 10-phenanthroline and two O atoms from CrO4-. The hydrogen bonding O-H...O had central effect for crystal stability.

Gender Effect on Political Leaders’ Nonverbal Communicative Structure during the COVID-19 Crisis

During the COVID-19 pandemic, there has been intense interest in political leaders’ nonverbal communicative structures (NCS) during televised appearances. This study analyzes the effect of gender on leaders’ NCS and presents theoretical and analytical frameworks of gendered NCS. We analyzed 20 televised appearances by 10 heads of state (five males and five females) from democratic Western countries during the COVID-19 pandemic. The findings revealed that gender had a significant effect on leaders’ NCS, indicating that leaders presented NCS that corresponded to their gender. Male leaders’ masculine NCS included competition, warning, threatening, and scaring behavior, broad proxemics, tension leakage, and illustrative gestures, while female leaders presented feminine NCS of cooperativeness, emotional communication, empathy, optimism, eye contact, and flexible expressions. Furthermore, the effect of gender on leaders’ NCS had an interaction effect with the situation of the pandemic, indicating that countries with a female leader had fewer diseased and severe cases and more calmness and healing NCS. The conclusions present theoretical and analytical frameworks that explain the central effect of gender on contemporary leaders’ NCS. This study develops advanced distinctive profiles for male versus female leaders’ NCS of emotions, cognition, and behavior during a crisis.

Caloric Vestibular Stimulation Reduces the Directional Bias in Representational Neglect

Caloric vestibular stimulation (CVS) can temporarily reduce visuospatial neglect and related symptoms. The present study examined the effect of CVS on representational neglect during free exploration of the map of France. We asked patients to name cities they could mentally “see” on the map of France, without giving them any directional instructions related to the left or right sides of the map. In right brain damaged patients with left visuospatial neglect, the mental representation of the map was asymmetrical (favoring the right side). After stimulation, neglect patients named more towns on the left side of the map, leading to a significant reduction in map representation asymmetry. Our findings are consistent with previous studies on visuospatial neglect and are in favor of a central effect of vestibular stimulation on mechanisms involved in space representation.

Medicines Used in Emergency

The aims of the study is to find the emergency medicines. The result Ine Epinephrine is a sympathomimetic, adrenergic group. Epinephrine effects can be seen in: Cardiovascular secondary hypotension, reversal epinephrine), gastrointestinal, uterine, bladder, respiratory, CNS, eye and metabolic processes. Clinical use can be seen in: Cardiovascular hypotension secondary, reversal epinephrine), gastrointestinal tract, uterus, bladder, breathing, CNS, eyes and metabolic processes. Stimulate the heart in patients with cardiac arrest and stop capillary bleeding. Ephedrine is a sympathomimetic, adrenergic class of drugs. The pharmacodynamics effect of ephedrine resembles the effect of epinephrine, the difference is that ephedrine is not a catecholamine, it is effective in oral administration, the duration of action is much longer, the central effect is stronger, but a much larger dose of epinephrine is needed, the difference being that ephedrine is not a catecholamine, it is effective in oral administration, its duration is much longer, the central effect is stronger, but a much greater dose is needed than the epinephrine dose. Like epinephrine, ephedrine acts on α, β1 and β2 receptors. The ephedrine cardiovascular effect resembles the effect of epi but lasts about 10 times longer.

Music in Detention and Interrogation

Luke Windsor explores the use of forced listening to music in detention and interrogation and points to the creation of ambiguity and uncertainty as a central effect. Windsor engages with several cases of psychological warfare during previous wars and highlights interrogation practices as described by the CIA and he seeks to identify the location of the boundary between the real and the imagined. The exploration of these cases, where music is used as a sound weapon, leads to a broader discussion of, first, the application of music in influencing behavior and, second, the ethics of the use of music in, for instance, marketing.