Classic articles in Apoptotic Research: A Bibliometric Analysis

BackgroundClassic articles are defined as research papers with a total citation of one thousand or more. The present study is to identify and analyse the characteristics of the classic articles in apoptosis research.MethodClassic articles with total of 1,000 or more citations from Web of Science Core Collection since year of publication to the end of 2017 were basically assessed regarding their document types, languages, journals, and Web of Science categories within 1900 to 2017.ResultThe study showed 418 classic documents in apoptotic research including 260 articles published between 1972 and 2012. The most productive Web of Science category was multidisciplinary sciences. Nature published most of these classic articles followed by Cell, and Science. The most productive country and institution were United States and Harvard University respectively. The author S.J. Korsmeyer from Harvard University was the most productive in apoptosis field and published 13 classic apoptosis articles while the author J.C Reed had more potential to publish classic apoptosis articles in future. The author J.C. Reed and V.A. Fadok had equal potential to publish the same number of classic articles as first- and corresponding-author. Article of Kerr et al. in 1972 was the most popular and cited apoptosis article. The most impact article in 2017 was article entitled “Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion” by Dong et al. in 2002.ConclusionThis study seems to identify the most industrious authors, institutions, and countries in the field of apoptosis research. It also tends to reveal the historical and discoveries related to the pathophysiology of apoptosis as well as the most impact publications on apoptosis studies.

Classification of Paper Values Based on Citation Rank and PageRank

PurposeThe number of citations has been widely used to measure the significance of a paper. However, there is a need in introducing another index to determine superiority or inferiority of papers with the same number of citations. We determine superiority or inferiority of papers by using the ranking based on the number of citations and PageRank.Design/methodology/approachWe show the positive linear correlation between Citation Rank (the ranking of the number of citation) and PageRank. On this basis, we identify high-quality, prestige, emerging, and popular papers.FindingsWe found that the high-quality papers belong to the subjects of biochemistry and molecular biology, chemistry, and multidisciplinary sciences. The prestige papers correspond to the subjects of computer science, engineering, and information science. The emerging papers are related to biochemistry and molecular biology, as well as those published in the journal “Cell.” The popular papers belong to the subject of multidisciplinary sciences.Research limitationsWe analyze the Science Citation Index Expanded (SCIE) from 1981 to 2015 to calculate Citation Rank and PageRank within a citation network consisting of 34,666,719 papers and 591,321,826 citations.Practical implicationsOur method is applicable to forecast emerging fields of research subjects in science and helps policymakers to consider science policy.Originality/valueWe calculated PageRank for a giant citation network which is extremely larger than the citation networks investigated by previous researchers.

What is Urgency of Health-Seeking Behaviour Concept in Health Policy?

Health-seeking behavior (HSB) is a concept that requires contributions from multidisciplinary sciences, namely health, psychology, and social sciences. Understanding the HSB concept helps academics and practitioners to understand the individual's reasons for seeking medical help. Health service facility factors are generally often blamed for the low quality of health in a place; for example, the low quality of health in the village is often associated with the limitations of health facilities in the village compared to in the city. It turns out that not all of them and not the majority of the low quality of health in an area is only due to the limitations of health facilities, sometimes it can be caused by the values held by the local community.

RISK MANAGEMENT IN THE CONTEXT OF MULTI-RISK ASSESSMENT

The late 20th and early 21st centuries were marked by sudden and rapid changes, including the free flow and interconnectedness of people, information, and trade, but the most prominent changes pertain to scientific and technological advancements. New connections were also found between different scientific disciplines, which had previously been considered unrelated, thus causing the breakthrough of multidisciplinary sciences. Unfortunately, the 21st century has so far been ridden with natural disasters worldwide. According to EM-DAT (Emergency Event Database 2015), the consequences and losses caused by natural disasters have been increasing. Thus, risk assessment became a priority for reducing the risk from natural disasters. Risk assessment is the essence of risk management. Just as there are connections between various scientific disciplines, so are there connections between various disastrous events, which resulted in the increased importance of the concept of multi-risk. Multi-hazard risk assessment is a key step in integrated risk management. Over the last decade, the interest in multi-risk assessment has grown in Europe but also globally.

Round table: Applying multidisciplinary sciences to improve paediatric primary care for children in Europe

Considerable progress has been made in improving child health and well-being in Europe over the past 40 years, with great reductions in neonatal, and child deaths, and in deaths from causes such as vaccine-preventable diseases. Paediatric primary care (PPC) has significantly contributed to these advances. However, there are still differences between and within countries regarding the content and organizations of primary care for children that might have an impact on important aspects such as access and availability of primary care. These cross-country and within-country differences together with current and future challenges in child health care, such as increasing prevalence of chronic and long-term conditions, fragmentation of care and shortage of health personnel, pose a complex challenge for European countries. Working towards an approach to tackle these challenges requires the vision, input and collaboration of multidisciplinary sciences. In this workshop four perspectives are brought together with the goal to learn from each other’s experiences and to establish a common knowledge base on how to collaborate between different disciplines and sciences to bring PPC to a next level. The first presentation will be from a public health perspective and is about the comparison of actual and desired organization and content of adolescent health services. The second presentation will be a paediatrician’s perspective and stresses the importance of an adequately trained paediatric workforce. The third presentation will be from a sociological perspective and focuses on the societal scale drivers framing health among children and their families. In the final presentation a philosophical perspective will be given on adherence to therapy, resilience and resonance in the treatment triangle of ‘patient-family-therapist’. The presentations will be followed by a round table discussion in which the audience will be involved: the presenters will answer questions and discuss with the audience how we should create better and sustainable PCP by making use of multiple disciplines and sciences. Key messages Differences between and within countries regarding the content and organizations of primary care for children might have an impact on important aspects such as access and availability of primary care. Working towards an approach to tackle challenges in paediatric primary care requires the vision, input and collaboration of multidisciplinary sciences.

MITOLOGI DAN SAINS: Bledug Kuwu di Kabupaten Grobogan

Bledug Kuwu is a unique mud volcano phenomenon located at Kuwu, Kradenan district, Grobogan Regency, Central Java. This area is far away from marine environment; however, this area contains high salinity hence none of plant and animal can live on this area. People believe about myth of arising mud volcano comes from the point where Joko Linglung, a giant snake, exit and enter the earth. Science has revealed about the origin of Bledug Kuwu and its potential. In this paper, Bledug Kuwu will be described from the local myth and multidisciplinary sciences.

ZnO and TiO2 Nanoparticles Genotoxicity According to their Structural and Morphological Characteristics Used for Medical Purposes

Defined by their small size, nanomaterials rapidly developed due to their physicochemical properties at nanoscale. Nanoparticles possess a high biological reactivity compared to their bulk size suggesting a high toxicity when the genetic material is involved. Nanogenotoxicity field refers to multidisciplinary sciences relevant for evaluation of genotoxic effect of various nanostructured materials. Due to their widespread use in medical area, zinc oxide and titanium dioxide nanoparticles are receiving researcher�s attention. The major objective of this work was to find a relationship between the structure and morphology of ZnO and TiO2 nanoparticles and their genotoxic potential.