At the beginning of the XXI century, human civilization has made anincredible break through in all spheres of science and life. Gradually,progress open edupmore and morenewop portunities for humanity and ways to solve problems. It seem edthat such a termas "forcemajeure" could eventually disappear from legal practice. However, theend of 2019 and the whole of 2020 showed theo pposite, as th eworld faced a new problem. A new challenge for humanitywasthevirus SARS-CoV-2, which inturnled to the emergence of a new "international" mode of the pandemic coronavirus COVID-19. The question of combating a new thre at hasarisen before the whole world. At a time when the world has notinvente done hundred percent effectived rugsagainst COVID-19, the only salvation for humanity is the quarantine mode, whichis a series of specific responsibilities and restrictions to combat the viraldisease. Despite the relative similarity of quarantine modes in different countries, the situation is very different. Thus, in some countries, the relative stability of COVID-19 distribution problems is relative lystable, and in others, despite the measures taken, the situation is exacerbated, the problem is developing rapidly. Unfortunately, the situation in Ukraine is also very ambiguous. Although the author it iesim posera ther strictrestrictions, the situation is gradually deteriorating. Thereis a questionof a real and effective quarantine mode, which will not only provide an opportunity to solve the problem and the possibility of sane existence of the state in a pandemic but also all ow you toquick lyget out of the quarantine mode and return to regular life. Thus, there is a need to investigate the administrative and legal regime of quarantine in Ukraine. It is necessary to identify the problems of the domestic routine and find appropriate ways to solve them, taking into account the global situation of the pandemic, as well as the successful experience and mistakes of other countries in the fight against the virus.