Vitamin D and gastric cancer: A systematic review and meta-analysis

Object:To explore the correlation between serum vitamin D level and the occurrence and pathological grade of gastric cancer.Data sources:Search the PubMed, Embase, Web of Science, Cochrane,Chinese Journal Full-text Database (CNKI), Wanfang Science and Technology Journal Full-text Database, Chinese Science and Technology Journal Full-text Database (VIP), Chinese Biomedical Literature Database (CBM), All articles about the correlation between serum vitamin D levels and gastric cancer published before July 2021.Results:10 trials with 1159 cases of gastric cancer patients and 33387 cases of normal control patients were analyzed. The serum vitamin D level of the gastric cancer group(15.56±7.46ng/ml) was lower than the control group (17.60±1.61ng/ml), and the difference was statistically significant (MD=-8.28, 95%CI: -14.32~-2.23, P <0.00001). The patients with gastric cancer clinical stage III/IV(16.19±8.04ng/ml) is lower than that of patients with stage I/II (19.61±9.61ng/ml), and the patients with low differentiation of gastric cancer is (17.5± 9.5ng/ml) is lower than that of well or moderately differentiated patients (18.04±7.92ng/ml), and the patients with lymph node metastasis (19.41±8.63ng/ml) is lower than that of patients without lymph node metastasis (20.65± 7.96ng/ml), the difference is statistically significant;Conclusions:Vitamin D levels are negatively correlated with the occurrence of gastric cancer. Vitamin D levels are significantly correlated with different clinical stages, degrees of differentiation and lymph node metastasis, suggesting that low vitamin D levels may be a predictor of poor prognosis in gastric cancer.

Функционирование вербального хезитатива ни / ней ‘это самое’ в устной монологической речи башкир (на материале диалектных текстов башкирского языка)

The article studies the functioning of the verbal hesitation marker ni / nei ‘whatchamacallit’ in Bashkir spontaneous speech. Goals. The research aims to analyze and identify the main functions of the investigated hesitation marker in the process of organizing spontaneous discourse. Materials and Methods. The study explores dialectal materials included in the text database of the dialectological cluster within the Digital Corpus (lit. ‘Machine Fund’) of the Bashkir Language (https://mfbl2.ru). The total of the studied materials is 209 dialectal texts. The database contains 718 tokens of the investigated hesitation marker. The selection of examples for analysis was carried out through the method of continuous sampling. The employed research methods are those of discourse and contextual analysis, as well as the statistical method. Results. Asemantization of the basic meaning of the interrogative pronoun in spontaneous speech results in the emergence of a pragmatic meaning, and the lexeme begins to function as a filler for hesitational pauses. The multifunctionality of this hesitation marker is confirmed by numerous examples of its use. In spontaneous speech, the verbal hesitation marker performs the hesitative (fills in pauses in speech production), discursive (as a means to organize speech) and search (temporary substitutions in search for a speech unit corresponding to the original intention) functions. The uniqueness of this hesitation marker is that in spontaneous speech it can replace any notional word that one has ‘on the tip of the tongue’ and, thus, help avoid the occurrence of long pauses or interruptions in utterances. The analysis of materials reveals the main methods of correcting problem areas in speech production. Being a characteristic attribute of spontaneous speech, the lexemes can also be stylistically used in fiction works as instruments to reveal the author’s intention — depicting a psychological portrait of the character through the latter’s speech features.

300–500 Threshold of Context Memory and Assumption Experiment

This chapter investigates the threshold of context memory on numbers 300 through 500 regarding perspective with assumption experiment and theories of cognitive semantics and short-term memory. Context generation became possible with text database with lexical engineering system on artificial intelligence (AI). It was realized an infinite and continuous presentation of context. Several context presentations realized the limitation of context memory on the process of continuous context presentation on numbers 500 and 2,000, as well as the representation process with judgement for memory. The first report studied the context generating machine for Japanese pun generation. This was termed “Class B engine” or “Dajare Machine.” This study focused on the examination of the context threshold using an experiment of human brain mapping on an auditory evoked magnetic field (AEF) of a magnetic encephalogram. It also focused on the analysis of the theory of cognitive semantics and folk biology, using a theory of short-term memory of the “magical number seven.”

Effectiveness and safety of brain-computer interface technology in the treatment of poststroke motor disorders: a protocol for systematic review and meta-analysis

IntroductionAbout 85% of stroke survivors have upper extremity dysfunction, and more than 60% have continuing hand dysfunction and cannot live independently after treatment. Numerous recent publications have explored brain-computer interfaces technology as rehabilitation tools to help subacute and chronic stroke patients recover upper extremity movement. Our study aims to synthesise results from randomised controlled trials to assess the effectiveness and safety of brain-computer interface technology in the treatment of poststroke motor disorders（PSMD）.Methods and analysisEnglish and Chinese search strategies will be conducted in eight databases: the China National Knowledge Infrastructure, Chinese Scientific Journal Database, Wanfang Database, China Doctoral Dissertations Full-Text Database, China Master’s Theses Full-Text Database, Cochrane Central Register of Controlled Trials, PubMed and Embase. In addition, manual retrieval of research papers, conference papers, ongoing experiments and internal reports, among others, will supplement electronic retrieval. The searches will select all eligible studies published on or before 8 June 2020. To enhance the effectiveness of the study, only randomised controlled trials related to brain-computer interface technology for poststroke motor disorders will be included. The Fugl-Meyer Motor Function score will be the primary outcome measure; the Modified Barthel Index, Modified Ashworth Score and the upper extremity freehand muscle strength assessment will be secondary outcomes. Side effects and adverse events will be included as safety evaluations. To ensure the quality of the systematic evaluation, study selection, data extraction and quality assessment will be independently performed by two authors, and a third author will handle any disagreement. Review Manager V.5.3.3 and STATA V.15.1 will be used to perform the data synthesis and subgroup analysis.Ethics and disseminationThis systemic review will evaluate the efficacy and safety of brain-computer interface technology combined with routine rehabilitation treatment for treatment of poststroke motor disorders. Since all included data will be obtained from published articles,the review does not require ethical approval. The review will be published in a peer-reviewed journal.PROSPERO registration numberCRD42020190868.

Saúde Ocupacional aplicada à Dança

O setor da dança está pouco retratado em contexto de Saúde Ocupacional e a bibliografia é razoavelmente escassa. Neste setor o profissional pode apenas efetuar ensaios e atuações (a solo ou em equipa), pode dar aulas para eventuais futuros colegas e/ ou para leigos ou acumular ambas as vertentes. Trata-se de uma Revisão Bibliográfica, iniciada através de uma pesquisa realizada em agosto de 2020 nas bases de dados “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina e RCAAP”. A dança é uma arte complexa, cujo instrumento é o corpo. Conjuga movimento com a emoção, servindo também como forma de comunicação. Em alguns estilos de dança a rotina de treinos é muito exigente e competitiva, de forma a aperfeiçoar departamentos como força, resistência, velocidade, flexibilidade, equilíbrio e controlo. Aos treinos intensos, por vezes, associam-se algias e lesões concretas. Por exemplo, no Ballet clássico, a exigência técnica é muito elevada e desafiante e, na bibliografia selecionada, é certamente a dança mais estudada neste contexto. A escassa bibliografia encontrada incide sobretudo nas principais lesões associadas (quer acidentes de trabalho, quer doenças profissionais); sendo que alguns artigos também destacam o eventual consumo de substâncias psicoativas em algumas modalidades específicas. Os autores elaboraram uma descrição dos principais Fatores de Risco/ Riscos Laborais deste setor, no geral; bem como listaram as Medidas de Proteção (coletivas e individuais) que consideram ser mais adequadas. O setor da dança está muito pouco estudado pela Saúde Ocupacional, sendo pertinente a análise da realidade portuguesa, sobretudo em alguns estilos muito desenvolvidos no nosso país e sobre os quais não se encontrou qualquer bibliografia específica (mesmo em contexto internacional). PALAVRAS-CHAVE: dança, bailarino, saúde ocupacional e medicina do trabalho.

Lexicography

The history of Egyptian lexicography is marked by the early twentieth-century Wörterbuch der ägyptischen Sprache (Wb). The decades after the appearance of the Wb saw the publication of many specialized dictionaries of language phases and corpuses. Ancient Egyptian lexicography is conditioned by sampling issues and the discontinuous nature of the artefactual record, by cultural distance, and by the nature of the writing systems of Egyptian. Current studies in Egyptian lexicography develop a variety of approaches, ranging from the more philological to the more linguistic. Since the publication of the Wb, many new texts have been published and many new words and meanings have been attested, while the lemmatization of the Wb (i.e. the process of grouping together the inflected forms of a word so that they can be analysed as a single item, identified by the word’s lemma, or dictionary form) appears in need of partial revision. The debate as to whether to produce a new comprehensive dictionary or a general text database based on the lexicon has been decided in favour of the latter in the 1990s. While digital textual databases based on the lexicon are being built, several voices call for a new dictionary, observing that a thesaurus does not replace a lexicographer’s work.

Meta-analysis of Bailing Capsule After Renal Transplantation

To objectively evaluate the effectivity and safety of Bailing Capsule After Renal Transplantation. Search Chinese Journal Full-text Database (CNKI), Chinese Science and Technology Periodical Full-text Database (VIP), Wanfang Database, PubMed, SCI, EMBase, The Cochrane Library database. Chinese uses "Bai Ling Capsule" "Kidney Transplant" as the search term, and English uses "Bailing Capsule","Bailing Jiaonang", "Corbrin Capsule", "CS-C-Q80", "Kidney transplant", "Renal transplant", etc. as search terms. Two people screened, extracted data, quality assessment and data analysis of the retrieved articles according to the inclusion criteria and exclusion criteria.A total of 10 studies were included, including 1580 patients. Meta analysis results:the experimental group was more effective than the control group in SCr level（ WMD = -28.40，95% CI： -45.87 ~ -10.94， Z = 3.19， P =0.001）、BUN levels（ WMD = -0.72，95% CI： -1.18 ~ -0.25， Z = 3.02， P =0.003）、 ALT levels( WMD = -6.05，95% CI：- 9.26 ~ -2.85， Z = 3.70， P = 0.0002）、AST levels（ WMD = -11.96，95% CI： -19.2 5~ -4.68， Z = 3.22， P = 0.001）.But the experimental group did not show significant effects in reducing the incidence of acute rejection.（ OR = 0.45，95% CI： 0.19 ~ 1.11， Z = 1.74， P =0.08）Compared with the control group, Bailing Capsule treatment group has obvious advantages in Improvement of liver and kidney function after renal transplantation1,but did not show good clinical results in reducing the incidence of acute rejection.

Effects of moxibustion on symptoms of mild cognitive impairment: protocol of a systematic review and meta-analysis

IntroductionMild cognitive impairment (MCI) is considered the intermediate phase between normal age-related cognitive decline and dementia. Moxibustion has gained increased popularity for the management of MCI in China.This study aimed to evaluate the effects and safety of moxibustion on symptoms of MCI.Methods and analysisFour English databases and six Chinese databases will be searched from their inception to October 2019: Embase, MEDLINE, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine Database, China National Knowledge Infrastructure, Chongqing VIP Chinese Science and Technology Periodical Database, Wanfang Database, SinoMed, China Doctoral Dissertations Full-text Database and the China Master’s Theses Full-text Database. Only clinical randomised controlled trials and the first period in randomised cross-over trial related to moxibustion for MCI will be included. The primary outcomes include the improvement of cognitive function, as measured by validated assessment tools. The secondary outcomes include changes in the activity of daily living scale, effective rate and the incidences of adverse events. The selection of studies, data extraction and risk of bias assessment will be carried out by two independent reviewers. Review Manager V.5.3 software will be used for statistical analyses. Heterogeneity test, data synthesis and subgroup analysis will be performed if necessary. The risk of bias of included studies will be assessed by theCochrane Handbookrisk of bias tool. Evidence quality will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation system.Ethics and disseminationEthics approval is not required as no private information from individuals are collected. The results will be published in a peer-reviewed journal or disseminated in relevant conferences.Trial registration numberCRD42018112657.