Analisis Survival dengan Menggunakan Metode Kaplan Meier pada Penderita Penyakit Demam Berdarah Dengue (DBD)

The Kaplan Meier method is one of the methods in survival analysis that is used to find out how big the chances of survival of a person suffering from a certain disease. The Kaplan Meier method calculates the patient's life by providing a definite survival proportion. The purpose of this study was to determine the relationship between age and length of treatment and patient status. The life chances of DHF patients using the Kaplan Meier method at the Lasinrang District Hospital. Pinrang. The results showed that there was no relationship between age and length of treatment as well as the status of DHF patients in Lasinrang Hospital Kab. Pinrang. The conclusion of this study is that the chance of survival of DHF patients before a patient dies is 100%. However, the chance of patient survival after 1 patient died during the observation was 99.1%. It is recommended that clinical monitoring should always be carried out, to predict the correct diagnosis of Dengue Virus Infection. And sero-epidemiological studies should continue to be carried out in many island capitals in Indonesia.

Does low income effects 5-year mortality of hepatocellular carcinoma patients?

Background In Korea, the universal health system offers coverage to all members of society. Despite this, it is unclear whether risk of death from hepatocellular carcinoma (HCC) varies depending on income. We evaluated the impact of low income on HCC mortality. Methods The Korean National Health Insurance sampling cohort was used to identify new HCC cases (n = 7325) diagnosed between 2004 and 2008, and the Korean Community Health Survey data were used to investigate community-level effects. The main outcome was 5-year all-cause mortality risk, and Cox proportional hazard models were applied to investigate the individual- and community-level factors associated with the survival probability of HCC patients. Results From 2004 to 2008, there were 4658 new HCC cases among males and 2667 new cases among females. The 5-year survival proportion of males was 68%, and the incidence per person-year was 0.768; the female survival proportion was 78%, and the incidence per person-year was 0.819. Lower income was associated with higher hazard ratio (HR), and HCC patients with hepatitis B (HBV), alcoholic liver cirrhosis, and other types of liver cirrhosis had higher HRs than those without these conditions. Subgroup analyses showed that middle-aged men were most vulnerable to the effects of low income on 5-year mortality, and community-level characteristics were associated with survival of HCC patients. Conclusion Having a low income significantly affected the overall 5-year mortality of Korean adults who were newly diagnosed with HCC from 2004 to 2008. Middle-aged men were the most vulnerable. We believe our findings will be useful to healthcare policymakers in Korea as well as to healthcare leaders in countries with NHI programs who need to make important decisions about allocation of limited healthcare resources according to a consensually accepted and rational framework.

Modelling the Effect of Microsite Influences on the Growth and Survival of Juvenile Eucalyptus globoidea (Blakely) and Eucalyptus bosistoana (F. Muell) in New Zealand

The effect of microsite on juvenile forest plantation yield is rarely explored. This is because juvenile plantation growth is considered to be reasonably homogenous due to a lack of resource competition between trees prior to canopy closure. However, models of juvenile plantation height growth and survival that are sensitive to microsite variation could aid decisions relating to site preparation, plantation establishment and early silvicultural treatments. In this study, juvenile Eucalyptus bosistoana and E. globoidea height growth and survival proportion were modelled against topographic and environmental microsite characteristics as independent variables. The experiment included three different sites situated in a sub-humid region of New Zealand. A total of 540 plots were planted with 18,540 trees in regular rows and columns. Micro-topographical variables significantly influenced height growth and survival proportion of both E. bosistoana and E. globoidea, but species differed in their responses. More sheltered microsites yielded greater height growth and survival for both species. The height of both species was influenced by wind exposure, morphometric protection, and distance from the nearest ridge. E. bosistoana height was also influenced by topographic position and surface plan curvature. Survival was affected by surface profile curvature for both species, while E. globoidea survival was also impacted by surface plan curvature and distance from the top ridge. This study identified microsite factors influencing juvenile height and survival of two Eucalyptus species.

Seed survival of Australian Acacia in the Western Cape of South Africa in the presence of biological control agents and given environmental variation

Studies of invasive Australian Acacia have shown that many seeds are still produced and accumulate in soil stored seed banks regardless of the presence of seed-targeting biological control agents. This is despite claims of biological control success, although there is generally a lack of data on the seed production of invasive Australian Acacia before and after the release of the respective agents. We aimed to quantify seed production and seed survival of invasive Australian Acacia currently under biological control. The seed production and survival (proportion of aborted, predated and surviving seeds) of A. longifolia, A. pycnantha and A. saligna were each studied at four to five sites in the Western Cape of South Africa. The relationships between seed production and stand characteristics were determined and the relative effects of seed predation and abortion on seed survival were established. The investigated invasive Australian Acacia produced many seeds that survived the pre-dispersal stage despite long-term presence of released biological control agents. It was shown that seed crop size is the only significant factor influencing seed survival of the studied Australian Acacia species. Furthermore, the seeds surviving per tree and per square meter were related to tree size. No quantitative evidence was found to suggest that seed-reducing biological control agents are having an impact on the population dynamics of their Australian Acacia hosts. This study illustrates the importance of studying the seed ecology of invasive plants before biological control agents are selected and released.

Improvement on The Ellis and Roberts Viability Model

With data sets of germination percent and storage time of seed lot of wheat and sorghum stored at three different storage temperature(t, °C) with three different water content (m, %) of seeds, together with data set of buckwheat and lettuce reported in literatures, the possibility that seed survival curve were transformed into line by survival proportion and the relationship that logarithm of average viability period (logp50) and standard deviation of seed death distribution in time (δ)with t, m and interaction between t and m were analysed. Result indicated that survival proportion transformed seed survival curve to line were much easier than the probability adopted by Ellis and Roberts, and the most important factor affecting logp50 and δ of seed lot was interaction between t and m. Thus, Ellis and Roberts viability model were suggested to be improved as Ki=Vi-p/10K-CWT (t×m) to predict longevity of seed lot with initial germination percent unknown, a new model of Gi/G0=A-P/10K-CWT(t×m) was constructed to predict longevity of seed lot with initial germination percent already known.

Soil adaptation of transgenic in vitro carrot plantlets

SUMMARYAdapting in vitro transgenic carrots to soil is the most crucial step preceding the field investigation of transgenic carrots. A low proportion of plants, around 0·20, acclimatize to soil (Hardegger & Sturm 1998) and thus prohibit the generation of high-expression carrot lines. In the present paper, a protocol for an efficient soil transfer is presented and the impact of carrot cultivar, soil substrate, tissue culture, and transformation process on transfer process is analysed. Somatic embryo germinants of Daucus carota cv. Rote Riesen 2 and Lobbericher Gelbe Futtermoehre showed a tremendous survival proportion – up to 1·00 – when transferred to their optimal soil substrate: sandy and loamy soil, with low content of macro and micro elements and a pH of 5·8. By optimizing the conditions described here, the proportion of soil acclimatized transgenic carrot plants of D. carota Lobbericher Gelbe Futtermoehre was increased from 0·1 to 0·87, and for the cultivar Rote Riesen from 0·09 to 0·67.