Mapping the sex determination region in the Salix F1 hybrid common parent population confirms a ZW system in six diverse species

Within the genus Salix, there are approximately 350 species native primarily to the northern hemisphere and adapted to a wide range of habitats. This diversity can be exploited to mine novel alleles conferring variation important for production as a bioenergy crop, but also to identify evolutionarily important genes, such as those involved in sex determination. To leverage this diversity, we created a mapping population by crossing six Salix species (S. viminalis, S. suchowensis, S. integra, S. koriyanagi, S. udensis, and S. alberti) to common male and female S. purpurea parents. Each family was genotyped via genotyping-by-sequencing and assessed for kinship and population structure as well as the construction of 16 backcross linkage maps to be used as a genetic resource for breeding and selection. Analyses of population structure resolved both the parents and F1 progeny to their respective phylogenetic section and indicated that the S. alberti parent was misidentified and was most likely S. suchowensis. Sex determining regions were identified on Salix chromosome 15 in the female-informative maps for seven of the eight families indicating that these species share a common female heterogametic ZW sex system. The eighth family, S. integra S. purpurea, was entirely female and had a truncated chromosome 15. Beyond sex determination, the Salix F1 hybrid common parent population (Salix F1HCP) introduced here will be useful in characterizing genetic factors underlying complex traits, aid in marker-assisted selection, and support genome assemblies for this promising bioenergy crop.

Diversification of Archean tonalite-trondhjemite-granodiorite suites in a mushy middle crust

Tonalite-trondhjemite-granodiorite (TTG) suites are the dominant component of Earth’s first continents, but their origins are debated. The trace element concentrations of these rocks are conventionally linked to their source depths and inferred geodynamic settings with the implicit assumption that TTG compositions are source-controlled. Alternatively, their variable compositions may be caused by fractional crystallization in TTG plutons after emplacement and less clearly linked to source depth. Most TTGs in Archean mid-crustal exposures are the dominant component of igneous gray gneiss complexes; the processes that influence the evolution of TTG magmas in this setting are poorly understood. We present a petrological–geochemical model that explains the coexistence of TTGs in the middle crust with low-pressure and high-pressure geochemical trends, irrespective of tectonic setting or depth of the TTG source. We propose that mid-crustal TTGs were long-lived crystal mushes with compositions controlled by the separation of early-crystallizing plagioclase and melt. Using phase equilibrium modeling, we demonstrate that a suite of TTGs from the southern Superior Province in Canada represents variably plagioclase-rich and melt-rich fractions from a common parent magma. The behavior of plagioclase may have a strong influence on the geochemical trends of TTGs, including the degree of rare earth element fractionation. Our results suggest that trace element compositions of TTGs may not primarily reflect the depth of the source and cannot be used alone to infer Archean geodynamic settings.

Origin of alkali-rich volcanic and alkali-poor intrusive carbonatites from a common parental magma

The discrepancy between Na-rich compositions of modern carbonatitic lavas (Oldoinyo Lengai volcano) and alkali-poor ancient carbonatites remains a topical problem in petrology. Although both are supposedly considered to originate via fractional crystallization of a “common parent” alkali-bearing Ca-carbonatitic magma, there is a significant compositional gap between the Oldoinyo Lengai carbonatites and all other natural compositions reported (including melt inclusions in carbonatitic minerals). In an attempt to resolve this, we investigate the petrogenesis of Ca-carbonatites from two occurrences (Guli, Northern Siberia and Tagna, Southern Siberia), focusing on mineral textures and alkali-rich multiphase primary inclusions hosted within apatite and magnetite. Apatite-hosted inclusions are interpreted as trapped melts at an early magmatic stage, whereas inclusions in magnetite represent proxies for the intercumulus environment. Melts obtained by heating and quenching the inclusions, show a progressive increase in alkali concentrations transitioning from moderately alkaline Ca-carbonatites through to the “calcite CaCO3 + melt = nyerereite (Na,K)2Ca2(CO3)3” peritectic, and finally towards Oldoinyo Lengai lava compositions. These results give novel empirical evidence supporting the view that Na-carbonatitic melts, similar to those of the Oldoinyo Lengai, may form via fractionation of a moderately alkaline Ca-carbonatitic melt, and therefore provide the “missing piece” in the puzzle of the Na-carbonatite’s origin. In addition, we conclude that the compositions of the Guli and Tagna carbonatites had alkali-rich primary magmatic compositions, but were subsequently altered by replacement of alkaline assemblages by calcite and dolomite.

Overcoming barriers in cognitive-behavioral therapy for youth anxiety and obsessive-compulsive disorder: Addressing parent behaviors

Exposure-based cognitive-behavioral therapy (CBT) is a well-established treatment for anxiety disorders and obsessive-compulsive disorder (OCD) in youth. Although a majority of youth respond to CBT, a substantial portion remain symptomatic and/or experience a return of symptoms after completing a course of treatment. This highlights the need for further improvements to this evidence-based treatment. Given that parent behaviors can negatively influence treatment, addressing parental behaviors in CBT serves as a novel and promising treatment target to improve youth's therapeutic outcomes. The authors review three common parent behaviors that influence anxiety and treatment outcomes: family accommodation, parent anxious behaviors, and management of disruptive behaviors. The authors then discuss each behavior, its effect on anxiety/OCD and treatment, and how to address the behavior within the context of CBT. In doing so, therapeutic learning can be optimized to improve CBT outcomes for youth with anxiety disorders and/or OCD.

Comparative evolution of vegetative branching in sorghum

Tillering and secondary branching are two plastic traits with high agronomic importance, especially in terms of the ability of plants to adapt to changing environments. We describe a quantitative trait analysis of tillering and secondary branching in two novel BC1F2 populations totaling 246 genotypes derived from backcrossing two Sorghum bicolor x S. halepense F1 plants to a tetraploidized S. bicolor. A two-year, two-environment phenotypic evaluation in Bogart, GA and Salina, KS permitted us to identify major effect and environment specific QTLs. Significant correlation between tillering and secondary branching followed by discovery of overlapping sets of QTLs continue to support the developmental relationship between these two organs and suggest the possibility of pleiotropy. Comparisons with two other populations sharing S. bicolor BTx623 as a common parent but sampling the breadth of the Sorghum genus, increase confidence in QTL detected for these two plastic traits and provide insight into the evolution of morphological diversity in the Eusorghum clade. Correspondence between flowering time and vegetative branching supports other evidence in suggesting a pleiotropic effect of flowering genes. We propose a model to predict biomass weight from plant architecture related traits, quantifying contribution of each trait to biomass and providing guidance for future breeding experiments.

Development of an Aus-Derived Nested Association Mapping (Aus-NAM) Population in Rice

A genetic resource for studying genetic architecture of agronomic traits and environmental adaptation is essential for crop improvements. Here, we report the development of a rice nested association mapping population (aus-NAM) using 7 aus varieties as diversity donors and T65 as the common parent. Aus-NAM showed broad phenotypic variations. To test whether aus-NAM was useful for quantitative trait loci (QTL) mapping, known flowering genes (Ehd1, Hd1, and Ghd7) in rice were characterized using single-family QTL mapping, joint QTL mapping, and the methods based on genome-wide association study (GWAS). Ehd1 was detected in all the seven families and all the methods. On the other hand, Hd1 and Ghd7 were detected in some families, and joint QTL mapping and GWAS-based methods resulted in weaker and uncertain peaks. Overall, the high allelic variations in aus-NAM provide a valuable genetic resource for the rice community.

Modeling D2D Underlaying Cellular Network for Hotspot Communications with Poisson Cluster and Hole Processes

This paper develops a new approach to the modeling and analysis of device-to-device (D2D) underlaying multi-tier cellular network for the dense hotspot communications, which consist of macro base stations (MBSs), pico BSs (PBSs), femto BSs (FBSs). A typicl user equipment (UE) can work either in D2D mode or cellular mode. Considering the dense hotspot communications, this work employs Poisson point process (PPP) to model the locations of MBSs and PBSs, and uses Poisson cluster process (PCP) to model the ones of UEs and FBSs. The locations of PBSs are also modeled as the centers of hotspots, referred to as the centers of PCPs. UEs and FBSs cluster around the common parent process PBSs. To guard the cluster-edge UEs, the clustered-UE classification and modified fractional frequency reuse (FFR) are jointly used, by which both the UEs and FBSs are classified two sets, cluster-center UEs and cluster-edge UEs, cluster-center FBSs and cluster-edge FBSs, respectively. The total frequency band is divided into two orthogonal segments, one of which is shared by D2D devices, cluster-edge FBSs, and PBSs, and the other segment is shared by cluster-center FBSs and MBSs. For such clustered multi-tier network, by using the methods from PPP, PCP, and PHP, this paper presents a tractable approach for modeling and analyzing the performance of cellular and D2D networks and gives the statistical descriptions of the experienced interference at a typical receiver by using the approximated Poisson hole processes (PCP) theory. This yields the derivations of the coverage probabilities of both the D2D receivers and cellular destinations. In additon, during the analysis of cellular UEs, to derive the coverage probabilities, this paper specially constructs a UE association criterion as well as the derivations of both the association probabilities and the statistical descriptions of association distances for cluster-center and cluster-edge UEs. The simulations and numerical results exploit the effect of various network parameters on the network performance and give the insights in terms of the proposed schemes as well as the comparison between cluster-center and cluster-edge UEs.

The Power of D-hops in Matching Power-Law Graphs

This paper studies seeded graph matching for power-law graphs. Assume that two edge-correlated graphs are independently edge-sampled from a common parent graph with a power-law degree distribution. A set of correctly matched vertex-pairs is chosen at random and revealed as initial seeds. Our goal is to use the seeds to recover the remaining latent vertex correspondence between the two graphs. Departing from the existing approaches that focus on the use of high-degree seeds in $1$-hop neighborhoods, we develop an efficient algorithm that exploits the low-degree seeds in suitably-defined D-hop neighborhoods. Specifically, we first match a set of vertex-pairs with appropriate degrees (which we refer to as the first slice) based on the number of low-degree seeds in their D-hop neighborhoods. This approach significantly reduces the number of initial seeds needed to trigger a cascading process to match the rest of graphs. Under the Chung-Lu random graph model with n vertices, max degree Θ(√n), and the power-law exponent 2<β<3, we show that as soon as D> 4-β/3-β, by optimally choosing the first slice, with high probability our algorithm can correctly match a constant fraction of the true pairs without any error, provided with only Ω((log n)4-β) initial seeds. Our result achieves an exponential reduction in the seed size requirement, as the best previously known result requires n1/2+ε seeds (for any small constant ε>0). Performance evaluation with synthetic and real data further corroborates the improved performance of our algorithm.

Musical Engagement and Parent-Child Attachment in Families With Young Children During the Covid-19 Pandemic

The onset of the Covid-19 pandemic has disrupted the lives of families in the United States and across the world, impacting parent mental health and stress, and in turn, the parent-child relationship. Music is a common parent-child activity and has been found to positively impact relationships, but little is known about music’s role in parent-child interactions during a pandemic. The current study utilized an online questionnaire to assess the use of music in the home of young children and their parents in the United States and Canada during Covid-19 and its relationship with parents’ affective attachment with their child. Musical activity was high for both parents and children. Parents reported using music for both emotion regulation and to socially connect with their children. Parent-child musical engagement was associated with parent-child attachment, controlling for relevant parent variables including parent distress, efficacy, education, and parent-child engagement in non-musical activities. These results indicate that music may be an effective tool for building and maintaining parent-child relationships during a period of uncertainty and change.

Musical Engagement and Parent-Child Attachment in Families with Young Children During the Covid-19 Pandemic

The onset of the Covid-19 pandemic has disrupted the lives of families in the United States and across the world, impacting parent mental health and stress, and in turn, the parent-child relationship. Music is a common parent-child activity and has been found to positively impact relationships, but little is known about music’s role in parent-child interactions during a pandemic. The current study utilized an online questionnaire to assess the use of music in the home of young children and their parents in the USA and Canada during Covid-19 and its relationship with parents’ affective attachment with their child. Musical activity was high for both parents and children. Parents reported using music for both emotion regulation and to socially connect with their children. Parent-child musical engagement was associated with parent-child attachment, controlling for relevant parent variables including parent distress, efficacy, education and parent-child engagement in non-musical activities. These results indicate that music may be an effective tool for building and maintaining parent-child relationships during a period of uncertainty and change.