Anatomy of eyelids muscles

Objective of the research was to study up-to-date literary data concerning anatomical peculiarities of palpebral muscles and their supporting and retaining apparatus. Eye diseases have become common nowadays. Very fast development of computer technology and deterioration of ecological conditions are one of the most important factors affecting visual organ impairment. Age physiological changes of the eye and adjacent tissues aggravate the quality of human life as well. Meanwhile, the majority of changes can be corrected. Modern ophthalmology possesses a plenty of surgical techniques, and development of skills in cosmetology and new pharmacological agents ensure a desirable delay of aging and deterioration of the visual organ functions. All the above factors are unlikely to become achievements in medicine without comprehensive awareness of the visual organ anatomy and its auxiliary apparatus. A lot of diseases are associated with eyelids, and ectropion and ptosis of the lower or upper eyelid are the commonest of them. Hypertrophy of the upper part of the orbicular muscle causes ectropion. It is a condition in which the upper eyelid is turned outwards. Isolation of the upper tarsal muscle from the tarsal plate leads to the development of aponeurotic ptosis. Strain of the lower retaining ligament, palpebral fissure septum and capsular-palpebral ligament result in ectropion of the lower eyelid. The presented literary review contains up-to-date information concerning the structure of the muscles of the eyelids and adjacent and auxiliary structures, their functions and possible functional disorders are described. Conclusions. Еhe review of scientific literature dealing with anatomical studies of palpebral muscles and their main adjacent structures is indicative of great interest of scientists in this issue. Though our study has found certain disembodied data and unsystematized fragments in the literature available. In our opinion, compiling an appropriate handbook dealing with the data base available concerning anatomy of the eyelids will considerably improve the quality of numerous surgical operations in cosmetology and ophthalmology.

Impact of the COVID-19 Pandemic on Ophthalmic Practice. Historical Aspects and Clinical Examples

This article presents data on clinical ophthalmological manifestations of COVID-19 described in the literature, clinical examples that we met in pandemic conditions, COVID-19 including early and late manifestations, as well as references to studies conducted decades ago and aimed to evaluate the effects of coronavirus infection on the visual organ. The purpose of the most studies was to study the effect of COVID-19 on the visual organ indicate that the most common ophthalmological manifestation of this disease is conjunctivitis, which occurs in 3–10 % of cases. Our observations showed that patients with COVID-19, when applying for an appointment with an ophthalmologist after 1–3 months, make complaints about the feeling of dryness, discomfort in the eyes, itching and redness of the eyelids. These complains arose immediately after the illness and persisted during the above terms. This phenomenon can be explained by the fact that any inflammatory process occurring on the eye surface disrupts the process of lacrimation and leads to the emergence of dry eye syndrome. It is necessary to pay close attention to complaints from the visual organ not only in patients with COVID-19 in the early stages of the disease, but also in the coming months after stopping the acute pathological process. As studies have shown, coronavirus can involve the posterior segment of the eye in the pathological process, since this virus has a retinotropic effect. This hypothesis can be confirmed by the reports of several authors who studied with optical coherence tomography (OCT) the state of the retina 11–33 days after the onset of symptoms in patients with COVID-19. OCT data indicate the presence of hyperreflexive zones at the level of the ganglion cell layer and the plexiform layer, the severity of these zones being greater in the papillomacular bundle region. In addition, cases of thromboembolic complications affecting the vascular system of the eye are described. Considering the fact that in the development of thromboembolism of the central artery and retinal vein, therapy is as effective as possible in the first hours from the beginning of this pathological process development, close attention should be paid to patients’ complaints to visual impairment occurred against the background of coronavirus infection. The data presented in this article open up a range of possibilities for conducting new scientific research that will help to preserve the vision and health of our patients as effectively as possible.

Why does an ophthalmologist wear glasses?

The aim of the study was to identify the reasons for the personal use of vision correction tools by ophthalmologists and the importance of vision for the specialty. Materials and methods. An anonymous online survey was conducted, which was attended by 122 respondents, including 111 ophthalmologists. Results. The visual acuity of two eyes without correction among the respondents was 1.0 and higher in 51 people. The maximum corrected visual acuity with two eyes was: 1.0 and higher in 79 respondents; less than 1.0 to 0.7 inclusive in 12 (those who refrained from answering the question had uncorrected visual acuity of 1.0 and higher). More than half of the respondents (56) suffer from myopia. Among the respondents, 53 use point correction. Of the spectacle lenses, ophthalmologists prefer plastic ones more. 36 respondents use contact correction. Surgical interventions on the organ of vision were performed in 12 patients. All respondents noted that they do not have cataracts, glaucoma, diseases of the optic nerve and color perception disorders. The choice of specialty did not depend on the existing diseases of the visual organ in 101 doctors, 9 people noted the connection between the previous pathologies of the visual organ with the subsequent choice of profession. Conclusions. According to the results of the study, it is possible to note the high maximum corrected visual acuity of ophthalmologists. Despite this, some respondents experience inconveniences at work related to visual impairments. For themselves, ophthalmologists often choose eyeglass correction instead of contact. And of the spectacle lenses, they prefer plastic ones more. The reasons for the use of glasses or contact correction among doctors of this specialty are increased requirements for the quality of vision. Key words: ophthalmologist, myopia, vision, glasses.

THE MANAGEMENT ALGORITHM OF CHILDREN WITH REFRACTORY GLAUCOMA

This article presents an analysis of the results of the algorithm of management of children with refractory glaucoma which included: preparation and carrying out surgical treatment, analysis of postoperative period of children with refractory glaucoma. Thetotal number of children diagnosed with glaucoma was 478. Of them 82.1%, 410 children underwent surgical treatment. 30.2% (125 children) needed reoperation. The results of the analysis of the clinical and functional state of the visual organ in children for the period from 2016 to 2020 are given. The indications for repeated surgical treatmentwith the use of drains are described in detail. Keywords: refractory glaucoma, drains, diagnosis, congenital glaucoma

The Ukrainian Scientific Medical Youth Journal (SUPPLEMENT)

We invite you to review the published abstracts at the XIII Іnternational Scientific and Practical Conference of students and young scientists "Special issues of diagnosis and treatment of diseases of the ENT organs, craniofacial area and visual organ diseases" March 18-19, 2021 on the basis of the National Medical University. With the participation of the student scientific society named after OA Kisel and the Society of Young Scientists and Specialists of the National Medical University.

Cell-molecular mechanisms of progression of ophthalmological pathology on the background of influence of environmental factors. Literature review

Modern scientists are increasingly paying attention to the molecular mechanisms of diseases of the visual organ in conditions of anthropogenic pollution. Environmental pollution is mainly due to atmospheric emissions from the metallurgical, automotive, aviation and petrochemical industries, waste from livestock farms and due to the use of mineral fertilizers and pesticides. Ukraine ranks one of the first in Europe in terms of the amount of industrial dirt per capita. The aim of this literature review was to analyze the role of extra- and intracellular protein structures and molecular mechanisms of some pathological processes of the visual organ that occur under the influence of anthropogenic stress on the human body. Material and methods. Scientific publications in foreign and Ukranian journals on relevant topics in the last 5 years, the Internet resources. Research results and their discussion. The literature review expanded the scientific understanding of the role of reparative enzyme (MGMT), vascular endothelial growth factor, Bcl-2 family proteins, p53 and Ki 67 proteins, matrix metalloproteinases in some ophthalmic pathology. Anthropoecological environmental factors have been shown to cause oxidative stress due to mitochondrial dysfunction and apoptosis, which are a component of a complex pathophysiological process in the most common diseases of the visual analyzer. Conclusions. The study of molecular mechanisms of occurrence and progression of diseases of the visual organ with the participation of protein factors makes it possible to expand the understanding of the pathogenetic links of their development in order to predict the course of the pathological process, adequate treatment and prevention

BRAIN AND EYE AS POTENTIAL TARGETS FOR IONIZING RADIATION IMPACT: PART II – RADIATION CEREBRO-OPHTALMIC EFFECTS IN CHILDREN, PERSONS EXPOSED IN UTERO, ASTRONAUTS AND INTERVENTIONAL RADIOLOGISTS

Background. Ionizing radiation (IR) can affect the brain and the visual organ even at low doses, while provoking cognitive, emotional, behavioral, and visual disorders. We proposed to consider the brain and the visual organ as potential targets for the influence of IR with the definition of cerebro-ophthalmic relationships as the «eye-brain axis». Objective. The present work is a narrative review of current experimental, epidemiological and clinical data on radiation cerebro-ophthalmic effects in children, individuals exposed in utero, astronauts and interventional radiologists. Materials and methods. The review was performed according to PRISMA guidelines by searching the abstract and scientometric databases PubMed/MEDLINE, Scopus, Web of Science, Embase, PsycINFO, Google Scholar, published from 1998 to 2021, as well as the results of manual search of peer-reviewed publications. Results. Epidemiological data on the effects of low doses of IR on neurodevelopment are quite contradictory, while data on clinical, neuropsychological and neurophysiological on cognitive and cerebral disorders, especially in the left, dominant hemisphere of the brain, are nore consistent. Cataracts (congenital – after in utero irradiation) and retinal angiopathy are more common in prenatally-exposed people and children. Astronauts, who carry out longterm space missions outside the protection of the Earth’s magnetosphere, will be exposed to galactic cosmic radiation (heavy ions, protons), which leads to cerebro-ophthalmic disorders, primarily cognitive and behavioral disorders and cataracts. Interventional radiologists are a special risk group for cerebro-ophthalmic pathology – cognitive deficits, mainly due to dysfunction of the dominant and more radiosensitive left hemisphere of the brain, and cataracts, as well as early atherosclerosis and accelerated aging. Conclusions. Results of current studies indicate the high radiosensitivity of the brain and eye in different contingents of irradiated persons. Further research is needed to clarify the nature of cerebro-ophthalmic disorders in different exposure scenarios, to determine the molecular biological mechanisms of these disorders, reliable dosimetric support and taking into account the influence of non-radiation risk factors. Key words: ionizing radiation, brain, eye, cerebro-ophthalmic effects, radiation emergencies, prenatal irradiation, space flights, interventional radiology.

Working conditions and occupational risks of anterior eye pathology in metalworking machine operators

Introduction. The profession of “machine operator in metalworking”, one of the most common professions in various industries, characterized by a large volume of abrasive operations, accompanied by dust formation, which creates a potential for the occurrence of diseases of the visual organ.The aim of the study is to provide a hygienic assessment of working conditions and occupational risk of visual organ pathology in metalworking machine operators.Materials and methods. Observation groups — machine operators for metalworking of two training groups (experience up to 5 years, experience of 6–20 years). Two comparison groups (administrative and technical personnel of the enterprise) are formed according to the same age-experience principle.Results. The working conditions of machine operators were classified as class 3.2. taking into account the severity and intensity of the work process and the noise level (80 dBA) in the workplace. Nitrogen oxide, carbon monoxide, and manganese were registered in the air of the working area in concentrations below the permissible concentration (PC), and the aerosol dihydroxide was registered above the PC in 25.8% of cases. In the main working groups, diseases of the anterior segment of the eye were more often registered, among which dry eye syndrome (DYS) prevailed (94.1%), chronic blepharoconjunctivitis (79.9%), persistent corneal opacification (21.7%). There was an increase in the prevalence of detected diseases with an increase in work experience (p≤0.05). In machine operators, the frequency of inhibition of lacrimal formation and decreased stability of the tear film was recorded significantly more often, with increasing work experience, the degree of violation of lacrimal formation and stability of the tear film increased. The chances of detecting pathology of the anterior segment of the eye in machine operators are 5.9 and 3.5 times higher than in the comparison group. There are different forces of connection, increasing with the increase of work experience in the profession, between the working conditions of machine operators and the occurrence of SHG (relatively strong), with chronic blepharoconjunctivitis and persistent corneal opacity (medium strength), which suggests the professional conditionality of this pathology.Conclusions. The results obtained suggest that the pathology of the anterior segment of the eye is professionally conditioned in metalworking machine operators and necessitate the introduction of preventive measures aimed at protecting the visual organ.

Multimorbidity of ischemic diseases of the visual organ and chronic cerebral ischemia in atherosclerosis

The purpose of this research was to study the features of the comorbid course of ischemic diseases of the visual organ and chronic cerebral ischemia in atherosclerosis. The material for this study was the results of complex examinations of 37 patients (74 eyes) with ischemic diseases of the visual organ in combination with chronic cerebral ischemia and atherosclerotic vascular lesions. In addition to complex ophthalmologic examination, ultra¬sound examination with color Doppler mapping of ex-tracranial and intracranial segments of the great vessels of the brain, Color-Doppler sonography and magnetic resonance imaging of the brain with tractography were used to study the peculiarities of the course of ischemic diseases of the visual organ in chronic cerebral ischemia. The quantitative characteristics of blood flow in the ves¬sels of the eye and brain were the maximum systolic, final diastolic speeds, resistance index, carotid – ophthalmic ratio.

Case report of rare congenital malformations of the nasal cavity, pharynx and ear in combination with a malformation of the visual organ on the example of a child, born from parents in a relative marriage

The authors present a case of congenital malformations of ENT organs in children, multiple congenital malformations of the nasal cavity, pharynx, ear and eyes (double tongue of the pharynx, atresia of the chianti on the left, atresia of the external auditory canal on the left, microphthalmia on the left) and congenital bilateral deafness. The peculiarity of this observation is the rarity of cases of many congenital defects of the ENT organs: doubled tongue of the pharynx, atresia of the choana on the left, atresia of the external auditory canal on the left, congenital bilateral deafness, in the combination of the organ of vision – the eye: microphthalmia on the left in a child who has a history of kinship of parents.