The last global economic crisis has prompted new dynamics in the scope of economic integration: On the one hand, the Transatlantic economy witnessed the formation of the largest economic integration in the human history: the Transatlantic Trade and Investment Partnership (TTIP). On the other hand, Shanghai Cooperation Organization (SCO) recently adopted the economic vision for initiating an economic integration. Since both integration projects were recently launched, this chapter is intended to make a small contribution to the limited scientific resources available to policymakers, academicians, NGOs, etc. In this respect, this chapter first presents a set of political, economic, institutional, and natural conditions suggested in the principal economic integration literature for the success of a regional economic bloc. Second, it aims at evaluating the TTIP and the SCO in the light of these success conditions.