The article describes the work of the Irkutsk branch of the Russian-Chinese Bank from the moment of its formation to the further reorganization (1898–1910). The financial performance indicators of credit institution in the period from 1901 till 1907, as reflected in the inspection in November, 1908, are given. Examines the reasons for loss of the branch related to the General decline of the business sector of the regional economy. The article notes the moment when the Bank branch management changed. The article describes the prospects for the development of the Department in connection with the course taken for lending to coal-producing enterprises of the Irkutsk province. Some quantitative calculations are given that demonstrate the possibility of growth of financial indicators of the institution. The article records the concern of competing credit institutions about the development of the local branch of the Russian-Chinese Bank. In conclusion, the circumstances that hindered the prospects for the development of the Department, in connection with the event held in 1910, are given. Russian-Chinese and Northern banks merge, resulting in the formation of a new credit institution-the Russian-Asian Bank.