Social entrepreneurship is a rapidly growing discipline that is attracting the interest of governments, researchers, media, and organizations. Social enterprises have the ability to impact nations economically, environmentally, and socially by solving most pressing problems such as poverty, hunger, pollution, and education to name but a few through provision of their innovative products and services. So, in order for social enterprises including special schools to function effectively and efficiently, deliver innovative and quality services, and achieve their goals, they need sufficient sources and funding. Many researchers also cite that lack of funding is one of the greatest challenges and this is further aggravated due to lack of proper marketing of their services. Hence, adopting an exploratory research design and mixed method approach, the objective of this chapter is to apprehend the challenges of social enterprises in special education with a focus on schools, especially in emerging economies.