Collagen-based materials in reproductive medicine and engineered reproductive tissues

Collagen, the main component of mammal skin, has been traditionally used in leather manufacturing for thousands of years due to its diverse physicochemical properties. Collagen is the most abundant protein in mammals and the main component of the extracellular matrix (ECM). The properties of collagen also make it an ideal building block for the engineering of materials for a range of biomedical applications. Reproductive medicine, especially human fertility preservation strategies and reproductive organ regeneration, has attracted significant attention in recent years as it is key in resolving the growing social concern over aging populations worldwide. Collagen-based biomaterials such as collagen hydrogels, decellularized ECM (dECM), and bioengineering techniques including collagen-based 3D bioprinting have facilitated the engineering of reproductive tissues. This review summarizes the recent progress in applying collagen-based biomaterials in reproductive. Furthermore, we discuss the prospects of collagen-based materials for engineering artificial reproductive tissues, hormone replacement therapy, and reproductive organ reconstruction, aiming to inspire new thoughts and advancements in engineered reproductive tissues research. Graphical abstract

Case Report: Medicolegal evaluation in a case of fatal scald where a child fell into a cauldron in rural Nepal

Thermal injuries in young children involving the buttocks, perineum, and lower limbs raise suspicion of child abuse. Determining the manner of death and ruling out homicide in a fatal case of scalding remains a challenge for forensic practitioners. One such issue is reported in the present case report, where a medicolegal evaluation of a fatal scald in a two-year-old girl child is discussed. Young children sustaining serious injuries from scalds is a grave social concern. Such young lives need to be protected from scald injuries whether accidental or purposeful. Differences in injury patterns on the basis of their distribution and their characteristics are important to determine manner of death in such cases.

Delayed Employment Among College Students in Guangdong – Taking Shenzhen University as an Example

Changes in social structure and macro-environment have gradually made “delayed employment” a key area of social concern. This paper assumes the college students from Shenzhen University as research subjects, conducts a special research on delayed employment, explores the employment needs and status quo of college students, analyzes the causes and results of this phenomenon, as well as provides students with a more comprehensive and accurate understanding of employment. This paper also aims to increase the employment rate of graduates, enable reasonable allocation and management of human resources, as well as improve the quality of employment in the society.

Efficacy of Ayurvedic herbal gel in the management of Dandruff: A case study

Dandruff (Darunak)is the common skin disease affecting the scalp area with the presence of itching, hair fall, dryness of scalp and dander. It is affecting the half of the adult population of either gender worldwide. Even though the prevalence is so high, its etiology being varied the treatment modalities are also different. Although dandruff is not among those disease to cause severe illness or morbidity, but it has a lot of social concern which reflects individual’s confidence and self-esteem. This paper aims to present clinical case study presentation with diagnosis using advance technique of Trochoscopy and the management of dandruff with the topical application of Dashemani Kandughna gel which showed excellent results.

Food Waste: Treatments, Environmental Impacts, Current and Potential Uses

Food waste is a major environmental and social concern, and its impact will most likely increase as the population grows [...]

PEMBERDAYAAN LEMBAGA PENDIDIKAN FORMAL DI BANGKA DALAM PENANAMAN GEREJA BARU

Social concern in the formation of Christian character and faith through non-profit educational institutions that have not been a special concern of Christians. Meanwhile, Christ must be the main part in the character of church leadership and secular leadership in the future. Through formal educational institutions such as Kindergartens and Elementary Schools, the church can contribute in participating in the intellectual life of the nation from an early age with the principle of 'fearing God'. Educational institutions are long-term in the formation of the character of Christ which plays an important role for each generation in the welfare and salvation of generations. The Sustainability Service can be expanded to carry out joint activities. the evidence of the new church is as true church growth. Several strategies developed through the empowerment of formal educational institutions, and under the leadership of the Holy Spirit, are expected to contribute to the planting of new churches.Keywords: Social Care, Formal educational institutions, Fear of God

Social buffering of human fear is shaped by gender, social concern, and the presence of real vs virtual agents

The presence of a partner can attenuate physiological fear responses, a phenomenon known as social buffering. However, not all individuals are equally sociable. Here we investigated whether social buffering of fear is shaped by sensitivity to social anxiety (social concern) and whether these effects are different in females and males. We collected skin conductance responses (SCRs) and affect ratings of female and male participants when they experienced aversive and neutral sounds alone (alone treatment) or in the presence of an unknown person of the same gender (social treatment). Individual differences in social concern were assessed based on a well-established questionnaire. Our results showed that social concern had a stronger effect on social buffering in females than in males. The lower females scored on social concern, the stronger the SCRs reduction in the social compared to the alone treatment. The effect of social concern on social buffering of fear in females disappeared if participants were paired with a virtual agent instead of a real person. Together, these results showed that social buffering of human fear is shaped by gender and social concern. In females, the presence of virtual agents can buffer fear, irrespective of individual differences in social concern. These findings specify factors that shape the social modulation of human fear, and thus might be relevant for the treatment of anxiety disorders.

Prediction of Farmers’ Income in Hebei Province Based on the Fractional Grey Model (1,1)

The problem of increasing farmers’ income has been a hot issue of social concern. Understanding the farmers’ income and the overall development trend is conducive to the rational layout of the social economy and promotes the steady development of a well-off society. Based on this, the paper selects the per capita disposable income (PCDI) of farmers’ households from 2012 to 2019 in 11 cities of Hebei Province as the research object and applies the fractional grey model (FGM (1,1)) to predict farmers’ income from 2020 to 2024. The results show that the farmers’ income will increase in the next five years. However, the growth rate of farmers’ income is slow in the areas with a large base of farmers’ income and strong in the areas with a small base of farmers’ income. The area with the highest trend in the growth rate of farmers’ income is Zhangjiakou and the lowest place is Handan. Only Shijiazhuang’s income growth rate is on the rise. Finally, suggestions are given to promote farmers’ income in Hebei Province.

Análisis ético de los deportes electrónicos: ¿un paso atrás respecto al deporte tradicional? (Ethical analysis of esports: a step backwards compared to traditional sports?)

Los deportes electrónicos, también conocidos como esports, son un rompedor fenómeno basado en competiciones deportivas en las que el ser humano desarrolla y entrena capacidades mentales y físicas bajo el uso de videojuegos competitivos. Su especial acercamiento a las nuevas generaciones ha creado cierta preocupación social sobre la educación, concretamente ética, que ofrece esta manifestación a los más jóvenes. Apoyados en la corriente hermenéutica, nuestro objetivo es analizar, desde un prisma ético, el fenómeno de los esports y como pueden contribuir, están contribuyendo o podrían contribuir a que sus practicantes tengan una vida plena. Entre los elementos analizados encontramos el proceso de virtualización, la corporalidad, la libertad, la virtud, el autoconocimiento o la violencia. Tras el análisis, se puede concluir que esta preocupación y crítica socialmente asentada no está fundamentada pues los deportes electrónicos pueden contribuir a un desarrollo ético del individuo y, con éste, a su educación. De esta forma, el desarrollo ético del sujeto contribuye al desarrollo ético de la sociedad. Algunos aspectos desarrollados pueden las concepciones de corporalidad, género y feminismo, la democratización de la competición humana, la disonancia entre la realidad y la virtualidad, la concepción de la agresividad, la violencia y la catarsis, la idea de libertad como existencia auténtica o las implicaciones del juego y del deporte en la humanidad. Abstract: Electronic sports, also known as esports, are a groundbreaking phenomenon based on sports competitions in which the human beings develops and trains mental and physical abilities using competitive videogames. Its special approach to the new generations has created certain social concern about education, specifically ethics, which this manifestation offers to the youngest. Supported by the hermeneutical current, our objective is to analyse, from an ethical prism, the phenomenon of esports and how they can contribute, are contributing or could contribute to their practitioners having a fulfilling life. Among the analysed elements we find the process of virtualization, corporeality, freedom, virtue, self-knowledge or violence. After the analysis, it can be concluded that this socially based concern and criticism is not founded, since electronic sports can contribute to an ethical development of the individual and, with this, to his education. In this way, the ethical development of the subject contributes to the ethical development of society. Some aspects developed can be the conceptions of corporeality, gender and feminism, the democratization of human competition, the dissonance between reality and virtuality, the conception of aggressiveness, violence and catharsis, the idea of freedom as authentic existence or the implications of the game and sport in humanity.