Late prehistoric eastern Tennessee polities provide a setting to examine relationships between biological stress and increasing emphasis on intensive maize agriculture, sedentism, population size, and differential access to protein-based dietary resources. This chapter compares bioarchaeological patterns between two Mississippian palisaded sites in Eastern Tennessee during the local Dallas Phase, A.D. 1300–1500. Toqua was a multi-mound center likely home to the main chief or chiefs of the region, while Citico was a smaller, palisaded locale with a single mound. Statistically significant patterns demonstrate that non-elites from Toqua possessed higher prevalence of all stress markers. Sex-based divisions are also noted in their mortuary program, with males typically interred in mounds and women in the village; Betsinger attributes this to simultaneous heterarchical expressions of different activity spheres. Further, there are few biological disparities between elite and non-elite females, which is considered the result of elite-sponsored, male-centered feasting that drove expressions of inequality during the twilight of the Mississippian era.