Quercetin-Based Modified Porous Silicon Nanoparticles for Enhanced Inhibition of Doxorubicin-Resistant Cancer Cells

2016 ◽  
Vol 6 (3) ◽  
pp. 1601009 ◽  
Author(s):  
Zehua Liu ◽  
Vimalkumar Balasubramanian ◽  
Chinmay Bhat ◽  
Mikko Vahermo ◽  
Ermei Mäkilä ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Cancer Cells ◽  
Silicon Nanoparticles ◽  
Porous Silicon Nanoparticles

High loading of doxorubicin into styrene-terminated porous silicon nanoparticles via π-stacking for cancer treatments in vitro

RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 44660-44665 ◽  
Author(s):  
Bing Xia ◽  
Bin Wang ◽  
Wenyi Zhang ◽  
Jisen Shi
Keyword(s):  
Porous Silicon ◽  
Cancer Cells ◽  
Silicon Nanoparticles ◽  
High Loading ◽  
Cancer Treatments ◽  
Π Stacking ◽  
Porous Silicon Nanoparticles

Styrene-terminated PSiNPs were fabricated for high loading of doxorubicin via π-stacking, which exhibited an excellent capability for killing cancer cells.

scholarly journals Nanobody-displaying porous silicon nanoparticles for the co-delivery of siRNA and doxorubicin

2021 ◽  
Vol 9 (1) ◽  
pp. 133-147
Author(s):  
Terence Tieu ◽  
Marcin Wojnilowicz ◽  
Pie Huda ◽  
Kristofer J. Thurecht ◽  
Helmut Thissen ◽  
...  
Keyword(s):  
Side Effects ◽  
Porous Silicon ◽  
Cancer Cells ◽  
Targeted Delivery ◽  
Silicon Nanoparticles ◽  
High Drug ◽  
Drug Concentrations ◽  
Porous Silicon Nanoparticles

Targeted delivery of chemotherapeutics to cancer cells has the potential to yield high drug concentrations in cancer cells while minimizing any unwanted side effects.

Cyclodextrin-Modified Porous Silicon Nanoparticles for Efficient Sustained Drug Delivery and Proliferation Inhibition of Breast Cancer Cells

2015 ◽  
Vol 7 (41) ◽  
pp. 23197-23204 ◽  
Author(s):  
Alexandra Correia ◽  
Mohammad-Ali Shahbazi ◽  
Ermei Mäkilä ◽  
Sérgio Almeida ◽  
Jarno Salonen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Porous Silicon ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Silicon Nanoparticles ◽  
Proliferation Inhibition ◽  
Sustained Drug Delivery ◽  
Porous Silicon Nanoparticles

scholarly journals Mesoporous silicon nanoparticles for targeted two-photon theranostics of prostate cancer

2016 ◽  
Vol 4 (21) ◽  
pp. 3639-3642 ◽  
Author(s):  
Arnaud Chaix ◽  
Khaled El Cheikh ◽  
Elise Bouffard ◽  
Marie Maynadier ◽  
Dina Aggad ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Porous Silicon ◽  
Cancer Cells ◽  
Silicon Nanoparticles ◽  
Prostate Cancer Cells ◽  
Mesoporous Silicon ◽  
Two Photon ◽  
Porous Silicon Nanoparticles ◽  
Mannose 6 Phosphate

Porous silicon nanoparticles grafted with a mannose-6-phosphate analogue were designed for targeting prostate cancer cells.

Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections

2021 ◽  
Author(s):  
Byungji Kim ◽  
Qinglin Yang ◽  
Leslie W. Chan ◽  
Sangeeta N. Bhatia ◽  
Erkki Ruoslahti ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Broad Spectrum ◽  
Therapeutic Efficacy ◽  
Bacterial Infections ◽  
Silicon Nanoparticles ◽  
First Line ◽  
Gram Positive ◽  
Gram Negative ◽  
Porous Silicon Nanoparticles

RNAi-mediated immunotherapy provided by fusogenic porous silicon nanoparticles demonstrates superior therapeutic efficacy against both Gram-positive and Gram-negative bacterial infections compared with first-line antibiotics.

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