scholarly journals The Addition of C‐Reactive Protein and von Willebrand Factor to MELD‐Na Improves Prediction of Waitlist Mortality

Hepatology ◽  
2021 ◽  
Author(s):  
Patrick Starlinger ◽  
Joseph C. Ahn ◽  
Aidan Mullan ◽  
Georg P. Gyoeri ◽  
David Pereyra ◽  
...  
1999 ◽  
Vol 19 (12) ◽  
pp. 3071-3078 ◽  
Author(s):  
Agnes Jager ◽  
Victor W. M. van Hinsbergh ◽  
Piet J. Kostense ◽  
Jef J. Emeis ◽  
John S. Yudkin ◽  
...  

1992 ◽  
Vol 68 (06) ◽  
pp. 678-682 ◽  
Author(s):  
F Andreotti ◽  
D R Hackett ◽  
A W Haider ◽  
M C Roncaglioni ◽  
G J Davies ◽  
...  

SummaryPlasma von Willebrand factor, plasminogen activator inhibitor activity and C-reactive protein were assessed as markers of coronary recanalisation in 30 patients with acute myocardial infarction receiving tissue-type plasminogen activator (t-PA). Blood samples were taken before t-PA (time 0), 4-hourly for 24 h and daily up to 72 h. A continuous electrocardiogram was recorded in the first 24 h. Coronary arteriography was performed 90 min and 24 h after the start of t-PA. Patients with a patent infarct artery (n = 17), compared to those with occluded artery (n = 13), showed a fall in von Willebrand factor from 0 to 24 h (p = 0.001), a greater fall in plasminogen activator inhibitor from 24 to 48 h (p = 0.04) and a fall in C-reactive protein from 48 to 72 h (p = 0.002). The accuracy of these indices compared favourably with time to peak plasma MB creatine kinase and ≥ 50% resolution of maximal ST-deviation on the electrocardiogram.Thus, changes in plasma von Willebrand factor, plasminogen activator inhibitor and C-reactive protein during the first 3 days of myocardial infarction are indicative of thrombolytic efficacy. Their concordant behaviour may reflect a common regulatory mechanism.


2002 ◽  
Vol 89 (9) ◽  
pp. 1133-1135 ◽  
Author(s):  
Arthur J. Siegel ◽  
Jack H. Mendelson ◽  
Michelle B. Sholar ◽  
Jane C. McDonald ◽  
Kent B. Lewandrowski ◽  
...  

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