Thyroid Disorders in Pregnant Women With Type I Diabetes

Author(s):  
Lois Jovanovic ◽  
Charles M. Peterson
2016 ◽  
Vol 65 (6) ◽  
pp. 45-51 ◽  
Author(s):  
Ludmila Yu Orekhova ◽  
Anna A Aleksandrova ◽  
Ludmila A Aleksandrova ◽  
Ramila S Musaeva ◽  
Gulrukhsor Kh Tolibova ◽  
...  

Introduction. More and more researches dedicated to the communication of diseases of the oral cavity of pregnant women with diabetes. It is proved that the intensity of caries and inflammatory periodontal diseases (gingivitis and periodontitis) increase significantly during pregnancy, while the presence of comorbidities, such as diabetes, increase these indexes.Aim. The aim of the work was to study the dental status of pregnant women with diabetes.Materials and methods. The study compared women with gestational diabetes mellitus, type 1 diabetes, and type 2 diabetes, to a control group of pregnant women without diabetes. In addition to clinical research methods, liquid-based cytology of the contents of the gingival sulcus was performed.Results. The results of clinical and laboratory studies have shown that inflammatory diseases of periodontium and teeth within pregnant women with diabetes are more common than within the pregnant women without this disease. It should be noted that the frequency of occurrence and severity of these diseases in the pregnant women with type I diabetes is higher than in the other groups.Conclusion. Pregnant women with diabetes are at risk for dental disease and require more attention from dentists, endocrinologists and obstetricians. The use of liquid-based cytology method helps in the diagnosis of inflammatory periodontal diseases.


2007 ◽  
Vol 10 (6) ◽  
pp. A267-A268
Author(s):  
AJ Holman ◽  
V Munro ◽  
S Nielsen ◽  
AC Lloyd

2019 ◽  
Vol 3 (25) ◽  
pp. 43-45
Author(s):  
I. I. Krukier ◽  
V. V. Avrutskaya ◽  
A. A. Grigoriants ◽  
A. S. Degtyaryova ◽  
A. A. Nikashina ◽  
...  

Objective of research was to study the production of serum and placental cytokines and relaxin in women with a physiological pregnancy (45) and complicated by type I diabetes mellitus (42). The research material was the placenta and serum of pregnant women, in which determined the level of cytokines TNF-α, TGF-β, IL-1β and relaxin. It has been shown that the cytokine-producing function of the placenta plays an important role in the development of that organ, and systemic production of cytokines and relaxin is of key importance in the development of endothelial dysfunction syndrome. Early diagnosis of complications in pregnant women with type 1 diabetes will make it possible to start etiopathogenetic therapy in a timely manner and makes it possible to perform adequate obstetric tactics of labor.


2021 ◽  
Vol 28 (02) ◽  
pp. 171-175
Author(s):  
Ajeet Kumar ◽  
Syeda Urooj Riaz ◽  
Om Prakash ◽  
Dileep Kumar ◽  
Ishaq Ghauri ◽  
...  

Objective: The aim of this study is to determine the frequency of thyroid disorders in patients with type-I diabetes mellitus. Study Design: Descriptive Cross-sectional study. Setting: Jinnah Medical College Hospital, Karachi. Period: 3rd January 2018 to 3rd July 2018. Material & Methods: A total number of hundred patients having NIDDM taking insulin were included and thyroid hormones were measured. Results: Out of hundred patients, 57 were male and 43 were female. Mean age was 12 to 20 years. Thirty-four (34%) of patients had a family history of type-I diabetes. The mean (±SD) age of patients when the type-I diabetes first diagnosed was 12(±3.08) years. A total of 6% patients had a thyroid dysfunction. Thyroid antibodies were negative among patients with deranged thyroid hormones and ultrasound thyroid gland was also normal. Conclusion: There is significant association of thyroid disorders with type-I diabetes mellitus. Frequent screening was recommended in these patients.


2012 ◽  
Vol 2 (3) ◽  
pp. 324-325
Author(s):  
S. Ferrazzani ◽  
E. Di Pasquo ◽  
S. Moresi ◽  
C. Martino ◽  
S. Salvi ◽  
...  

Author(s):  
T. A. Stewart ◽  
D. Liggitt ◽  
S. Pitts ◽  
L. Martin ◽  
M. Siegel ◽  
...  

Insulin-dependant (Type I) diabetes mellitus (IDDM) is a metabolic disorder resulting from the lack of endogenous insulin secretion. The disease is thought to result from the autoimmune mediated destruction of the insulin producing ß cells within the islets of Langerhans. The disease process is probably triggered by environmental agents, e.g. virus or chemical toxins on a background of genetic susceptibility associated with particular alleles within the major histocompatiblity complex (MHC). The relation between IDDM and the MHC locus has been reinforced by the demonstration of both class I and class II MHC proteins on the surface of ß cells from newly diagnosed patients as well as mounting evidence that IDDM has an autoimmune pathogenesis. In 1984, a series of observations were used to advance a hypothesis, in which it was suggested that aberrant expression of class II MHC molecules, perhaps induced by gamma-interferon (IFN γ) could present self antigens and initiate an autoimmune disease. We have tested some aspects of this model and demonstrated that expression of IFN γ by pancreatic ß cells can initiate an inflammatory destruction of both the islets and pancreas and does lead to IDDM.


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