Effect of chemical linkage upon the stability and cytotoxic activity of A chain immunotoxins

Author(s):  
Edward J. Wawrzynczak ◽  
Philip E. Thorpe
2021 ◽  
Vol 2101 (1) ◽  
pp. 012074
Author(s):  
Weixin Yu ◽  
Zhen Dai ◽  
Jifeng Zhao ◽  
Lulu Fang ◽  
Yiwen Zhang

Abstract The strength of P92 steel (tensile strength, specified plastic elongation strength) will decrease after its hardness is reduced, ferrite and carbides forming the structure. Carbides of grain size 5-6 are precipitated in the grains and grain boundaries. The martensite lath shape has completely disappeared. M23C6 carbide coarsened obviously, with a maximum size of about 500nm; The Laves phase is also aggregated and coarsened, connecting in a chain shape with a maximum size of more than 500nm. Evolution of microstructure, namely the obvious coarsening of M23C6 carbides and the aggregation and connection of Laves phases in a chain shape, are the main causes for rapid decrease in the stability of the material substructure and evident decline in mechanical properties and hardness. In addition, the MX phase did not change significantly, hardly affecting the hardness reduction of P92 steel.


2020 ◽  
Vol 2 (3) ◽  
pp. 1115-1121
Author(s):  
Philipp Bender ◽  
Lourdes Marcano ◽  
Iñaki Orue ◽  
Diego Alba Venero ◽  
Dirk Honecker ◽  
...  

Magnetospirillum gryphiswaldense biosynthesize high quality magnetite nanoparticles, called magnetosomes, and arrange them into a chain that behaves like a magnetic compass.


2019 ◽  
Vol 29 (3) ◽  
pp. 60-64
Author(s):  
М. М. Radomska ◽  
I. V. Horobtsov

The transformation of ecosystems at urban territories imposes serious threats to the well-being of its inhabitants, both human and non-human. Modern cities represent a random combination of natural and technogenic landscapes, which often have no connections, and therefore are not able to support animal populations. However, the stability of such clustered ecosystem is impossible without the provision of stable flow of energy and matter ensured by living organisms. Being vulnerable to the negative factors of the urban environment, animals are also able to reflect its condition, so by contributing to the diversity of urban fauna it is possible to increase the overall quality of living conditions in a city. However, animals in cities are represented by insects, rodents, domesticated animals and single ubiquist organism, which either cannot be monitored, form real populations or are not desired. Therefore birds are considered to be that part of zoocenosis, which are worth investing efforts in support and development. The research has been conducted to study the avifauna of Kyiv City and major threats to its diversity and populations. The major risks for birds at the territory of Kyiv are formed by the fragmentation of natural landscapes, introduction of new species, pollution of the environment, waste accumulation and physical factors of pollution, namely light and noise. In order to provide the conservation of existing bird associations it is offered to unite a chain of landscapes, joined by close location, well preserved phytocoenosis and favourable conditions for birds' living activity, into protected objects with corresponding legal status. The fundamental element of the future protected areas is chosen to be water bodies of the city. The analysis of suitable and available areas has output a structure of 4 cores, based on lakes of Svytoshynsky, Osokorky, Obolon and Desnyansky districts of Kyiv. They all possess the necessary feature to apply for protected status and are already habitats of urban avifauna. The success of this initiative should be supported by the creation of single management body for all protected areas of Kyiv. The investments in the implementation of the project are estimated and cover organizational and technical actions.


2012 ◽  
Vol 15 (08) ◽  
pp. 1250045 ◽  
Author(s):  
IHOR LUBASHEVSKY

A new emergence mechanism related to the human fuzzy rationality is considered. It assumes that individuals (operators) governing the dynamics of a certain system try to follow an optimal strategy in controlling its motion but fail to do this perfectly because similar strategies are indistinguishable for them. The main attention is focused on the systems where the optimal dynamics implies the stability of a certain equilibrium point in the corresponding phase space. In such systems the fuzzy rationality gives rise to some neighborhood of the equilibrium point, the region of dynamical traps, wherein each point is regarded as an equilibrium one by the operators. So, when the system enters this region and while it is located in it, maybe for a long time, the operator control is suspended. To elucidate a question as to whether the dynamical traps on their own can cause emergent phenomena, the stochastic factors are eliminated from consideration. In this case the system can leave the dynamical trap region only because of the mismatch between actions of different operators. By way of example, a chain of oscillators with dynamical traps is analyzed numerically. As demonstrated, the dynamical traps do induce instability and complex behavior of such systems.


The thermal decomposition of acetaldehyde, propionaldehyde, n -butyraldehyde and iso-butyraldehyde, as investigated by the static method, is essentially homogeneous, inhibitable by propylene, isobutene and small amounts of nitric oxide, and generally catalyzed at high inhibitor concentrations. The kinetic order of the uninhibited decomposition exhibits little obvious regularity, but that of the maximally inhibited reaction is approximately 1.5 for all three inhibitors. Kates of the uninhibited decomposition do not follow the sequence in the homologous series, and there is no systematic variation in the extent of inhibition from one aldehyde to another. For each aldehyde, the minimum rates for the three inhibitors in general are not identical, nevertheless exhibit a correspondence probably close enough to eliminate chance coincidence. The kinetic and analytical results of the uninhibited decomposition can be approximately described by a Kice-Herzfeld-type mechanism, with the kinetics in each case largely determined by the stability of radicals and their reactions in chain propagation and termination. The question whether the maximally inhibited reaction is a molecular reaction or a chain reaction is surveyed. Although the results cannot be completely accounted for by a molecular reaction alone, a chain mechanism for propylene inhibition involving allyl radicals likewise has only limited success. For nitric-oxide inhibition, it is not certain how far the results are affected by the occurrence of the subsequent catalyzed reaction. No definite conclusion can thus be reached about the nature of the maximally inhibited reaction.


2008 ◽  
Vol 18 (08) ◽  
pp. 2471-2476
Author(s):  
M. HAMILTON ◽  
O. F. DE ALCANTARA BONFIM

We present a simple lattice model consisting of a chain of coupled oscillators, where their masses are interconnected by linear springs and allowed to move along a common axis, as in a monorail. In the transverse direction each mass is also attached to two other springs, one on each side of the mass. The ends of these springs are kept at fixed positions. The nonlinearity in the model arises from the geometric constraints imposed on the motion of the masses, as well as from the configuration of the springs, where in the transverse directions the springs are either in the extended or compressed state depending on the position of the mass. Under these conditions we show that solitary waves (domain walls) are present in the system. In the long wavelength limit an analytical solution for these nonlinear waves is found. Numerical integrations of the equations of motion in the full discrete system are also performed to analyze the stability of the domain wall solution. Nonlinear supratransmission is also shown to exist in the model and a discussion of mechanism is presented.


2013 ◽  
Vol 9 (4) ◽  
pp. 744-752 ◽  
Author(s):  
Justin C. Thomas ◽  
Joanne M. O’Hara ◽  
Lei Hu ◽  
Fei P. Gao ◽  
Sangeeta B. Joshi ◽  
...  

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