Follicular Carcinoma of the Thyroid

1992 ◽  
pp. 16-31
Author(s):  
Robert P. Fiedler
Keyword(s):  
Follicular Carcinoma

Socio-demographic and Clinical Characteristics of Patient with Thyroid Cancer

2020 ◽  
Vol 11 (1) ◽  
pp. 54-58
Author(s):  
AKM Farhad Hossain ◽  
Md Mahmudur Rahman Siddiqui ◽  
Sayada Fatema Khatun
Keyword(s):  
Public Health ◽  
Thyroid Cancer ◽  
Clinical Characteristics ◽  
Family Income ◽  
Ethical Issues ◽  
Endocrine System ◽  
Public Health Problem ◽  
Follicular Carcinoma ◽  
Public Health Issue ◽  
Cross Sectional

Background: Thyroid cancer is the most common malignant disease in endocrine system. It is an emerging public health issue associated with burden on the family, community and the nation. The aim of this study is to determine the socio-demographic and clinical characteristics of patient with thyroid cancer attending in tertiary hospital. Methods: This cross sectional study was conducted among 246 thyroid cancer patients in two tertiary hospitals of Dhaka city from 01 July 2018 to 30 June 2019. The subjects were selected purposively following specific selection criteria and maintaining ethical issues. Data were collected by face to face interview using a semi-structured questionnaire and checklist. Data were analyzed by the statistical package for the social science (SPSS) version 23. Results: This study revealed that majority (74.4%) of respondents was female, married (72%), housewife (61.4%), rural respondent (41.1%) and had primary education (69%). Mean (± SD) age of the respondent was 37.85(±12.20) years (Range 14-70 years) and mean (± SD) monthly family income was Tk. 17681(±10602). Out of 246 cases, 204 (82.9%) was papillary and 42 (17.1%) was follicular carcinoma. Various clinical presentations included visible neck swelling in 225 (91.5%), swollen lymph node in 103 (41.9%), pain 90 (36.6%), Difficulties in swallowing 87 (35.4%), Hoarseness of voice in 141 (57.3%), cough along with swelling 47(19.1%), Difficulties in breathing due to swelling in 13(5.3%) of the patients. Conclusion: Incidence of thyroid cancer has increased worldwide specially in female patients in 3rd and 4th decades of life. As thyroid cancer is a growing public health problem in Bangladesh, proper screening and early diagnostic facilities at all level should be available to measure its actual burden in the country. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 54-58

Clinical Menifestation and Anaylsis of Thyroid Follicular Carcinoma

2010 ◽  
Vol 53 (1) ◽  
pp. 30 ◽  
Author(s):  
Jeong A Mo ◽  
Guk Haeng Lee ◽  
Byeong Chol Lee ◽  
Myung Chul Lee ◽  
Moon Sang Jung ◽  
...  
Keyword(s):  
Follicular Carcinoma ◽  
Thyroid Follicular Carcinoma

THYROID TYPE CARCINOMA ARISING IN STRUMA OVARII. SIX CLINICAL CASES AND REVIEW

2018 ◽  
Vol 64 (6) ◽  
pp. 708-715
Author(s):  
Natalya Severskaya ◽  
Andrey Rodichev ◽  
Aleksey Ilin ◽  
Dmitriy Semin ◽  
Pavel Isaev ◽  
...  
Keyword(s):  
Radioiodine Therapy ◽  
Clinical Course ◽  
Case Reports ◽  
Thyroid Tissue ◽  
Follicular Carcinoma ◽  
Complete Response ◽  
Pelvic Surgery ◽  
Ovarian Teratoma ◽  
Struma Ovarii

Struma ovarii is a rare variant of the mature ovarian teratoma composed of more than 50% thyroid tissue. Thyroid type carcinoma can occur in 5% of struma ovarii. Given the rarity of this pathology, as well as the different clinical course, approaches to the treatment of this disease are controversial. The proposed approaches to treatment vary from ovarian resection to total hysterectomy with bilateral salpingo-oophorectomy and adjuvant therapy. We present here 6 case reports of thyroid type carcinoma in struma ovarii and outcome of patients treated in our clinic. All patients had pelvic surgery of different extent, followed by thyroidectomy and radioiodine therapy. The incidence of metastasis is 67% (4/6), 2 - intraperitoneal metas-tases, 2 - bone metastases. Among patients with metastases, 2 have reached a complete response, one with a good response continues treatment, one had progression. The follow-up period is 1 to 15 years (median 4 years). One patient with follicular carcinoma died of progression 8 years after diagnosis. The remaining patients are alive.

Late bone metastasis from an encapsulated follicular carcinoma of the thyroid withoutcapsular and vascular invasion

1996 ◽  
Vol 46 (6) ◽  
pp. 457-461 ◽  
Author(s):  
Yuji Mizukami ◽  
Akltaka Nonomura ◽  
Yoshinobu Hayashi ◽  
Kenji Ohmura ◽  
Takatoshi Michigishi ◽  
...  
Keyword(s):  
Bone Metastasis ◽  
Vascular Invasion ◽  
Follicular Carcinoma

scholarly journals Differential Diagnosis of Calvarial Tumors: A Series of 8 Cases

2021 ◽  
Author(s):  
Jitesh Kumar Sharma ◽  
Rashim Kataria ◽  
Madhur Choudhary ◽  
Devendra Kumar Purohit
Keyword(s):  
Bone Tumors ◽  
Primitive Neuroectodermal Tumor ◽  
Treatment Options ◽  
Follicular Carcinoma ◽  
Brown Tumor ◽  
Clinical Correlation ◽  
Skull Bone ◽  
Clinical Presentations ◽  
Tumor Metastases ◽  
Radiological Examinations

Abstract Introduction To present and discuss the clinical presentations, investigations, and treatment options for skull bone tumors. Materials and Methods This study was conducted from January 2019 to December 2019 at the Department of Neurosurgery. During this period, eight patients presented with skull bone tumor in the outpatient department. All patients were thoroughly investigated. Surgery was conducted on six patients and two patients had disseminated carcinoma; hence, surgery was not done. Patients were regularly followed-up after the surgery. Results In our study, out of eight cases, five were females and three were males. We had two cases of fibrous dysplasia, two cases of osteomas, and one case each of brown tumor, metastases from lung carcinoma, metastases from follicular carcinoma of thyroid, and Ewing sarcoma/primitive neuroectodermal tumor (PNET). Excision of tumor was performed where indicated and adjuvant chemo- and radiotherapy was suggested wherever required. Conclusion Bony tumors of the skull are uncommon diseases for the neurosurgeons. These tumors require a careful diagnosis with suitable radiological examinations and proper clinical correlation for proper management.

scholarly journals Advanced thyroid carcinomas: neural network analysis of ultrasonographic characteristics

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Michael Cordes ◽  
Theresa Ida Götz ◽  
Elmar Wolfgang Lang ◽  
Stephan Coerper ◽  
Torsten Kuwert ◽  
...  
Keyword(s):  
Neural Network ◽  
Imaging Modality ◽  
Follicular Carcinoma ◽  
Predictive Values ◽  
Thyroid Carcinomas ◽  
The Neural Network ◽  
Group 2 ◽  
Line Imaging ◽  
Hidden Layer ◽  
Group 1

Abstract Background Ultrasound is the first-line imaging modality for detection and classification of thyroid nodules. Certain characteristics observable by ultrasound have recently been identified that may indicate malignancy. This retrospective cohort study was conducted to test the hypothesis that advanced thyroid carcinomas show distinctive clinical and sonographic characteristics. Using a neural network model as proof of concept, nine clinical/sonographic features served as input. Methods All 96 study enrollees had histologically confirmed thyroid carcinomas, categorized (n = 32, each) as follows: group 1, advanced carcinoma (ADV) marked by local invasion or distant metastasis; group 2, non-advanced papillary carcinoma (PTC); or group 3, non-advanced follicular carcinoma (FTC). Preoperative ultrasound profiles were obtained via standardized protocols. The neural network had nine input neurons and one hidden layer. Results Mean age and the number of male patients in group 1 were significantly higher compared with groups 2 (p = 0.005) or 3 (p <  0.001). On ultrasound, tumors of larger volume and irregular shape were observed significantly more often in group 1 compared with groups 2 (p <  0.001) or 3 (p ≤ 0.01). Network accuracy in discriminating advanced vs. non-advanced tumors was 84.4% (95% confidence interval [CI]: 75.5–91), with positive and negative predictive values of 87.1% (95% CI: 70.2–96.4) and 92.3% (95% CI: 83.0–97.5), respectively. Conclusions Our study has shown some evidence that advanced thyroid tumors demonstrate distinctive clinical and sonographic characteristics. Further prospective investigations with larger numbers of patients and multicenter design should be carried out to show whether a neural network incorporating these features may be an asset, helping to classify malignancies of the thyroid gland.

Lymphocytic Infiltration in Pediatric Thyroid Carcinomas

2004 ◽  
Vol 7 (5) ◽  
pp. 487-492 ◽  
Author(s):  
Van H. Savell ◽  
Stephen M. Hughes ◽  
Charles Bower ◽  
David M. Parham
Keyword(s):  
Papillary Carcinoma ◽  
Follicular Carcinoma ◽  
Thyroid Neoplasms ◽  
Lymphocytic Infiltration ◽  
Lymphocytic Infiltrate ◽  
Low Grade ◽  
Lymphoid Infiltrate ◽  
Thyroid Carcinomas ◽  
Thyroid Papillary ◽  
Adults And Children

Lymphocytic thyroiditis has been associated with an increase in the incidence of thyroid papillary carcinoma in some reports, mostly series of both adults and children. Relatively little is written about thyroiditis and follicular carcinomas. We have seen several cases of pediatric follicular thyroid carcinomas, that had an associated lymphocytic infiltrate, which led us to examine all primary malignant thyroid neoplasms in our surgical files from 1984 through 2000 to examine this relationship. We also investigated the nature of the lymphocytic infiltrate with routine immunohistochemistry. Ten patients (five male, five female, ages 4.5–21 years of age) had a thyroid carcinoma resection, six (three males and three females) with papillary carcinoma and four patients (two males and two females) with low-grade follicular carcinoma. Seven samples (one male had two cases with tumor) from patients who had a papillary carcinoma resection with tissue blocks available were identified (one patient had slides but no blocks), as were all four patients with a follicular carcinoma. The thyroid of all patients with a follicular carcinoma contained a lymphocytic infiltrate; only four of the seven papillary carcinoma samples had an associated lymphoid infiltrate. In all cases with a lymphoid infiltrate, the infiltrate was present in both lobes (both adjacent and separate from the tumor). B lymphocytes were present in the lymphoid infiltrate of three of four patients with follicular carcinomas and in 1 of 3 cases of papillary carcinomas. T cells were dispersed throughout all the tumors with lymphoid infiltrates. We conclude that pediatric follicular carcinomas have an associated lymphocytic infiltrate in the tumor and/or adjacent thyroid, more commonly than papillary carcinomas.

HMGI(Y) gene expression as a potential marker of thyroid follicular carcinoma

2004 ◽  
Vol 389 (3) ◽  
pp. 193-197 ◽  
Author(s):  
W. Czyż ◽  
E. Balcerczak ◽  
M. Jakubiak ◽  
Z. Pasieka ◽  
K. Kuzdak ◽  
...  
Keyword(s):  
Gene Expression ◽  
Follicular Carcinoma ◽  
Potential Marker ◽  
Thyroid Follicular Carcinoma

scholarly journals RASPoint Mutations and PAX8-PPARγ Rearrangement in Thyroid Tumors: Evidence for Distinct Molecular Pathways in Thyroid Follicular Carcinoma

2003 ◽  
Vol 88 (5) ◽  
pp. 2318-2326 ◽  
Author(s):  
Marina N. Nikiforova ◽  
Roy A. Lynch ◽  
Paul W. Biddinger ◽  
Erik K. Alexander ◽  
Gerald W. Dorn ◽  
...  
Keyword(s):  
Follicular Carcinoma ◽  
Molecular Pathways ◽  
Thyroid Tumors ◽  
Thyroid Follicular Carcinoma
Sign in / Sign up

Export Citation Format

Share Document