Aging as Risk Factor in Eye Disease

2008 ◽  
pp. 1-8
Author(s):  
Luciano Cerulli
Keyword(s):  
Risk Factor ◽  
Eye Disease

scholarly journals Is Household Air Pollution a Risk Factor for Eye Disease?

2013 ◽  
Vol 10 (11) ◽  
pp. 5378-5398 ◽  
Author(s):  
Sheila West ◽  
Michael Bates ◽  
Jennifer Lee ◽  
Debra Schaumberg ◽  
David Lee ◽  
...  
Keyword(s):  
Air Pollution ◽  
Risk Factor ◽  
Household Air Pollution ◽  
Eye Disease

scholarly journals Evaluation of the contribution of matrix metalloproteinase gene polymorphism to the formation of glaucoma in men (analysis of three-locus gene models)

2020 ◽  
pp. 48-49
Author(s):  
Д.И. Свинарева
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Male Gender ◽  
Eye Disease ◽  
Open Angle ◽  
Is Research ◽  
The Matrix

Первичная открытоугольная глаукома (ПОУГ) - это хроническое заболевание глаз, сопровождающееся повышением внутриглазного давления и характерными изменениями поля зрения. Мужской пол является фактором риска развития глаукомы. Целью исследования явилось изучение роли трехлокусных моделей с участием 8 полиморфных локусов генов матриксных металлопротеиназ (rs679620 ММР3, rs1799750 ММР1, rs2250889, rs3918249, rs17576, rs3918249, rs3787268 и rs17577 ММР9) в формировании ПОУГ у мужчин. Нами выявлено 7 трехлокусных моделей SNP×SNP взаимодействий, определяющих подверженность к развитию ПОУГ у мужчин. Primary open-angle glaucoma (POAG) is a chronic eye disease accompanied by an increase in intraocular pressure and specific changes in the visual field. Male gender is a risk factor for glaucoma. The aim of the study is research the role of three-locus models with the participation of 8 polymorphic loci of the matrix metalloproteinases genes (rs679620 MMP3, rs1799750 MMP1, rs2250889, rs3918249, rs17576, rs3918889 and rs17577 MMP9) in the POAG formation among men. We have identified 7 three-locus models of SNP × SNP interactions that determine susceptibility to the development of POAG in men.

Serum Vitamin D Deficiency Is an Independent Risk Factor for Thyroid Eye Disease

2020 ◽  
Vol 36 (1) ◽  
pp. 17-20 ◽  
Author(s):  
Curtis J. Heisel ◽  
Alixandra L. Riddering ◽  
Christopher A. Andrews ◽  
Alon Kahana
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Vitamin D Deficiency ◽  
Independent Risk Factor ◽  
Serum Vitamin ◽  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Serum Vitamin D

Is Homelessness a Risk Factor for Eye Disease?

2005 ◽  
Vol 219 (6) ◽  
pp. 345-349 ◽  
Author(s):  
Susanne Pitz ◽  
Christina Kramann ◽  
Frank Krummenauer ◽  
Andreas Pitz ◽  
Gerhard Trabert ◽  
...  
Keyword(s):  
Risk Factor ◽  
Eye Disease

“ASSESSMENT OF VISUAL DISPLAY TERMINAL USE AS A RISK FACTOR FOR PAEDIATRIC DRY EYE DISEASE” : A CROSS SECTIONAL STUDY

2021 ◽  
pp. 55-58
Author(s):  
Souvik Ganguly ◽  
Sheuli Kumar ◽  
Sambuddha Ghosh ◽  
Debarshi Jana
Keyword(s):  
Risk Factor ◽  
Dry Eye ◽  
Ocular Surface ◽  
Visual Display ◽  
Cross Sectional Study ◽  
Eye Disease ◽  
Sectional Study ◽  
Outdoor Activity ◽  
Cross Sectional ◽  
Visual Display Terminal

Purpose: To assess Visual Display Terminal(VDT) exposure as a risk factor for paediatric Dry Eye Disease(DED). Methodology: In this cross sectional study, children(5-15 years) from both urban and rural regions with VDT(computer,smartphone,television) exposure(1-2,3-4,>=5hours) were enrolled. Dry eye evaluation was done using Ocular Surface Disease Index (OSDI) Questionnaire, Schirmer's without anesthesia, Fluorescein-Tear lm Break-up Time(F-TBUT) and corneal , conjunctival uorescein staining as per Tear Film and Ocular Surface Society(TFOS) Dry Eye Workshop II Guidelines 2017(DEWS II). DED diagnosis was based on OSDI grading(>=13) and objective tests(>=1 positive test). Results: 315 children exposed to VDTwere selected for the study. Burning sensation and redness were the most common symptoms. Prevalence of DED was observed to be 6.03%(19 children-38 eyes). Mean age and hours of VDT exposure was signicantly higher and hours of outdoor activity and sleep signicantly lower in DED children compared to NON DED children(p<.05). Urban elder children had highest DED prevalence rate of 13.19% .Prevalence of DED in children using VDTfor 1-2 hours was .74%,3-4 hours was 28.57%, and >=5 hours was 47.83% (p=<.001). Children with short hours of outdoor activity(<3hours) had DED prevalence of 24.62 % whereas children with longer outdoor activity(>=3 hours) showed 1.20% prevalence(p<.001). Children with less hours of sleep(<8hours) showed DED prevalence of 22.58% and those with longer hours(>=8 hours) of sleep had only 1.98% DED prevalence (p<.001). Conclusion: DED was found to be associated with elder age, longer hours of VDT exposure , short hours of outdoor activity and sleep in VDTexposed children.

scholarly journals Treatment Trends in Dry Eye Disease and Factors Associated with Ophthalmic Follow-up Discontinuation in Japan

2019 ◽  
Vol 8 (8) ◽  
pp. 1120 ◽  
Author(s):  
Miki Uchino ◽  
Norihiko Yokoi ◽  
Motoko Kawashima ◽  
Yamanishi Ryutaro ◽  
Yuichi Uchino ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Dry Eye ◽  
Past History ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
History Of

Despite the importance of dry eye disease (DED) treatment, the rate of DED treatment discontinuation, especially discontinuation of ophthalmic follow-up, remains unknown. This study aimed to assess the prevalence and risk factors of ophthalmic follow-up discontinuation for DED. A cross-sectional survey of 1030 participants was conducted using a self-administered web-survey instrument. We collected lifestyle information, history of DED diagnosis, types of treatment, frequency of eye-drop usage, symptoms, and the reasons for discontinuing treatment. Statistical analyses including logistic regression were used to evaluate the risk factors of discontinuing ophthalmic follow-up for DED. A past history of clinical DED diagnosis was reported by 155 (15.0%) subjects. Of those, 130 had persistent DED, and 88 (67.7%) of the subjects reported discontinuation of ophthalmic follow-up for DED. The most prevalent reasons for ophthalmic follow-up discontinuation were time restrictions, followed by dissatisfaction with the DED treatment. Duration after DED diagnosis was the only significant risk factor for discontinuing ophthalmic follow-up after adjusting for age and sex (odds ratio = 1.09, 95% confidence interval = 1.02–1.17, p = 0.009). In conclusion, longer DED duration after diagnosis was a significant risk factor for discontinuing ophthalmic follow-up for DED. This study showed that DED ophthalmic follow-up discontinuation involves both medical and non-medical reasons. Clinicians need to be aware of them, and preventative effort is needed to avoid discontinuation.

scholarly journals Corneal Sub-Basal Nerve Changes in Patients with Herpetic Keratitis during Acute Phase and after 6 Months

Medicina ◽  
2019 ◽  
Vol 55 (5) ◽  
pp. 214 ◽  
Author(s):  
Vilija Danileviciene ◽  
Reda Zemaitiene ◽  
Vilte Marija Gintauskiene ◽  
Irena Nedzelskiene ◽  
Dalia Zaliuniene
Keyword(s):  
Risk Factor ◽  
Nerve Fibre ◽  
Previous History ◽  
Eye Disease ◽  
Healthy Controls ◽  
Herpes Labialis ◽  
Corneal Sensitivity ◽  
History Of ◽  
Corneal Nerve ◽  
Branch Density

Background and objectives: The purpose of this study was to describe corneal sensitivity and the morphological changes of sub-basal corneal nerves using in vivo laser scanning confocal microscopy (LSCM) in herpes simplex virus (HSV) keratitis-affected eyes, and to compare with both contralateral eyes and with the eyes of patients with a previous history of herpes labialis but no history of herpetic eye disease, and with healthy patients with no history of any HSV diseases, during the acute phase of the disease and after six months. Materials and Methods: A prospective clinical study included 269 patients. All of them underwent a complete ophthalmological examination, Cochet-Bonnet aesthesiometry and LSCM within the central 5 mm of the cornea. After six months, all the patients with herpetic eye disease underwent the same examination. Serology tests of the serum to detect HSV 1/2 IgG and IgM were performed. Results: HSV-affected eyes compared with contralateral eyes, herpes labialis and healthy control group eyes demonstrated a significant decrease in corneal sensitivity, corneal nerve fibre density, corneal nerve branch density, corneal nerve fibre length and corneal nerve total branch density (p < 0.05). During follow up after six months, corneal sensitivity and sub-basal nerve parameters had increased but did not reach the parameters of contralateral eyes (p < 0.05). Previous herpes labialis did not influence corneal sensitivity and was not a risk factor for herpetic eye disease. Conclusions: Corneal sensitivity and sub-basal nerve changes in HSV-affected eyes revealed a significant decrease compared with contralateral eyes, and with the eyes of patients with a previous history of herpes labialis, and of healthy controls. Following six months, corneal sensitivity and sub-basal nerve parameters increased; however, they did not reach the parameters of contralateral eyes and the eyes of healthy controls. The best recovery of corneal sensitivity was seen in patients with epithelial keratitis. Herpes labialis was not a risk factor for herpetic eye disease.

scholarly journals Demographic profile and risk factors associated with dry eye disease in North Western Rajasthan, India

2019 ◽  
Vol 7 (7) ◽  
pp. 2721
Author(s):  
Meenu Jaju ◽  
Kalpna Jain ◽  
Surbhi Kanawa
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Risk Factor ◽  
Dry Eye ◽  
Rural Areas ◽  
Climatic Condition ◽  
Systemic Disease ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Age Group

Background: The aim was to study the demographic profile and analyze risk factor associated with dry eye disease in North West Rajasthan, India.Methods: This was a hospital-based study conducted in Department of Ophthalmology, Sardar Patel Medical College, Bikaner, Rajasthan. Sample size of this study was 100 patients. All participants underwent a general ophthalmic assessment including history of any previous ocular and systemic illness along with ocular examination on slit lamp and specific tests for dry eye (Schirmer's test and Tear film break up time) were performed.Results: Dry eye were seen maximum in age group 46 to 60 years (41%), followed by 61-75 years (23%). Female’s preponderance was seen compared with male. Dry eye patients belong from rural areas were (57%) while remaining (43%) from urban areas and among these highest were farmer/labourers (32%). Several known risk factors were found in this study which include post-menopause. Climatic condition like excessive wind, high temperature and computers users had strong association with dry eye. In Systemic disease rheumatoid arthritis was commonly associated with dry eye were. Smoking contact lens use were also associated with increased risk of developing dry eye.Conclusions: Dry eye disease are more common in older age group patients. Female’s preponderance were found in the study especially postmeopausal women. Dry eye disease are more common in patients belongs to rural areas. Risk factor associated with dry eye were Climatic condition like excessive wind, high temperature and computers users, systemic disease like rheumatoid arthritis Smoking, contact lens users.

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