Taking Research Outcomes to Target Beneficiaries: Research Uptake, Meaning and Benefits

Doing research inevitably involves making numerous decisions that can influence research outcomes in such a way that it leads to overconfidence in statistical conclusions. One proposed method to increase the interpretability of a research finding is preregistration, which involves documenting analytic choices on a public, third-party repository prior to any influence by data. To investigate whether, in psychology, preregistration lives up to that potential, we focused on all articles published in Psychological Science with a preregistered badge between February 2015 and November 2017, and assessed the adherence to their corresponding preregistration plans. We observed deviations from the plan in all studies, and, more importantly, in all but one study, at least one of these deviations was not fully disclosed. We discuss examples and possible explanations, and highlight good practices for preregistering research.

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Online, Asynchronous Data Collection in Qualitative Research

The Oxford Handbook of Methods for Public Scholarship ◽

10.1093/oxfordhb/9780190274481.013.28 ◽

2019 ◽

pp. 442-467

Author(s):

Tracy Spencer ◽

Linnea Rademaker ◽

Peter Williams ◽

Cynthia Loubier

Keyword(s):

Qualitative Research ◽

Data Collection ◽

Face To Face ◽

Research Outcomes ◽

Data Collection Strategy ◽

Time Distance ◽

Privacy Issues

The authors discuss the use of online, asynchronous data collection in qualitative research. Online interviews can be a valuable way to increase access to marginalized participants, including those with time, distance, or privacy issues that prevent them from participating in face-to-face interviews. The resulting greater participant pool can increase the rigor and validity of research outcomes. The authors also address issues with conducting in-depth asynchronous interviews such as are needed in phenomenology. Advice from the field is provided for rigorous implementation of this data collection strategy. The authors include extensive excerpts from two studies using online, asynchronous data collection.

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Counter-Predictive Research Outcomes.

Contemporary Sociology A Journal of Reviews ◽

10.2307/2067734 ◽

1981 ◽

Vol 10 (4) ◽

pp. 556

Author(s):

Marc Howard Ross ◽

Jean I. Martin

Keyword(s):

Research Outcomes ◽

Predictive Research

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Important research outcomes for treatment studies of perinatal depression: systematic overview and development of a core outcome set

BJOG An International Journal of Obstetrics & Gynaecology ◽

10.1111/1471-0528.16780 ◽

2021 ◽

Author(s):

Christel Hellberg ◽

Marie Österberg ◽

Ann Kristine Jonsson ◽

Sara Fundell ◽

Frida Trönnberg ◽

...

Keyword(s):

Perinatal Depression ◽

Core Outcome Set ◽

Core Outcome ◽

Important Research ◽

Systematic Overview ◽

Research Outcomes ◽

Outcome Set

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Investigator Initiated Clinical Trials (IICTs): A Systematic Search in Registries to Compare the Czech Republic and Portugal in Terms of Funding Policies and Scientific Outcomes

Therapeutic Innovation & Regulatory Science ◽

10.1007/s43441-021-00293-w ◽

2021 ◽

Author(s):

C. Madeira ◽

L. Hořavová ◽

F. dos Santos ◽

J. R. Batuca ◽

K. Nebeska ◽

...

Keyword(s):

Clinical Trials ◽

Czech Republic ◽

Clinical Research ◽

Systematic Search ◽

European Countries ◽

The Czech Republic ◽

Research Outcomes ◽

Funding Policies ◽

Funding Agencies ◽

First Time

Abstract Objectives Clinical trials provide one of the highest levels of evidence to support medical practice. Investigator initiated clinical trials (IICTs) answer relevant questions in clinical practice that may not be addressed by industry. For the first time, two European Countries are compared in terms of IICTs, respective funders and publications, envisaging to inspire others to use similar indicators to assess clinical research outcomes. Methods A retrospective systematic search of registered IICTs from 2004 to 2017, using four clinical trials registries was carried out in two European countries with similar population, GDP, HDI and medical schools but with different governmental models to fund clinical research. Each IICT was screened for sponsors, funders, type of intervention and associated publications, once completed. Results IICTs involving the Czech Republic and Portugal were n = 439 (42% with hospitals as sponsors) and n = 328 (47% with universities as sponsors), respectively. The Czech Republic and Portuguese funding agencies supported respectively 61 and 27 IICTs. Among these, trials with medicinal products represent 52% in Czech Republic and 4% in Portugal. In the first, a higher percentage of IICTs’ publications in high impact factor journals with national investigators as authors was observed, when compared to Portugal (75% vs 15%). Conclusion The better performance in clinical research by Czech Republic might be related to the existence of specific and periodic funding for clinical research, although further data are still needed to confirm this relationship. In upcoming years, the indicators used herein might be useful to tracking clinical research outcomes in these and other European countries.

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Protocol for establishing an Adaptive Diseases control Expert Programme in Tanzania (ADEPT) for integrating care of communicable and non-communicable diseases using tuberculosis and diabetes as a case study

BMJ Open ◽

10.1136/bmjopen-2020-041521 ◽

2021 ◽

Vol 11 (4) ◽

pp. e041521

Author(s):

Stellah G Mpagama ◽

Kaushik Ramaiya ◽

Troels Lillebæk ◽

Blandina T Mmbaga ◽

Marion Sumari-de Boer ◽

...

Keyword(s):

Operational Research ◽

Communicable Diseases ◽

Health Facilities ◽

Learning System ◽

Management Approach ◽

African Countries ◽

Non Communicable Diseases ◽

Research Outcomes ◽

The Government

IntroductionMost sub-Saharan African countries endure a high burden of communicable infections but also face a rise of non-communicable diseases (NCDs). Interventions targeting particular epidemics are often executed within vertical programmes. We establish an Adaptive Diseases control Expert Programme in Tanzania (ADEPT) model with three domains; stepwise training approach, integration of communicable and NCDs and a learning system. The model aims to shift traditional vertical programmes to an adaptive diseases management approach through integrating communicable and NCDs using the tuberculosis (TB) and diabetes mellitus (DM) dual epidemic as a case study. We aim to describe the ADEPT protocol with underpinned implementation and operational research on TB/DM.Methods and analysisThe model implement a collaborative TB and DM services protocol as endorsed by WHO in Tanzania. Evaluation of the process and outcomes will follow the logic framework. A mixed research design with both qualitative and quantitative approaches will be used in applied research action. Anticipated implementation research outcomes include at the health facilities level for organising TB/DM services, pathways of patients with TB/DM seeking care in different health facilities, factors in service delivery that need deimplementation and the ADEPT model implementation feasibility, acceptability and fidelity. Expected operational research outcomes include additional identified patients with dual TB/DM, the prevalence of comorbidities like hypertension in patients with TB/DM and final treatment outcomes of TB/DM including treatment-related complications. Findings will inform the future policies and practices for integrating communicable and NCDs services.Ethics and disseminationEthical approval was granted by The National Research Health Ethical Committee (Ref-No. NIMR/HQ/R.8a/Vol.IX/2988) and the implementation endorsed by the government authorities. Findings will be proactively disseminated through multiple mechanisms including peer-reviewed journals, and engagement with various stakeholders’ example in conferences and social media.

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