An Insight into the Bacterial Biogenesis of Silver Nanoparticles, Industrial Production and Scale-up

Author(s):  
Venkataraman Deepak ◽  
Kalimuthu Kalishwaralal ◽  
Sureshbabu Ram Kumar Pandian ◽  
Sangiliyandi Gurunathan
Author(s):  
Isabel Abad-Álvaro ◽  
Diego Leite ◽  
Dorota Bartczak ◽  
Susana Cuello ◽  
Beatriz Gomez-Gomez ◽  
...  

Toxicological studies concerning nanomaterials in complex biological matrices usually require a carefully designed workflow that involves handling, transportation and preparation of a large number of samples without affecting the nanoparticle...


2021 ◽  
Vol 09 ◽  
Author(s):  
Sarvat Zafar ◽  
Aiman Zafar ◽  
Fakhra Jabeen ◽  
Miad Ali Siddiq

: Nanotechnology studies the various phenomena of physio-chemical procedures and biological properties for the generation of nanosized particles, and their rising challenges in the various sectors, like medicine, engineering, agriculture, electronic, and environmental studies. The nanosized particles exhibit good anti-microbial, anti-inflammatory, cytotoxic, drug delivery, anti-parasitic, anti-coagulant and catalytic properties because of their unique dimensions with large surface area, chemical stability and higher binding density for the accumulation of various bio-constituents on their surfaces. Biological approaches for the synthesis of silver nanoparticles (AgNPs) have been reviewed because it is an easy and single-step protocol and a viable substitute for the synthetic chemical-based procedures. Physical and chemical approaches for the production of AgNPs are also mentioned herein. Biological synthesis has drawn attention because it is cost-effective, faster, non-pathogenic, environment-friendly, easy to scale-up for large-scale synthesis, and having no demand for usage of high pressure, energy, temperature, or noxious chemical ingredients, and safe for human therapeutic use. Therefore, the collaboration of nanomaterials with bio-green approaches could extend the utilization of biological and cytological properties compatible with AgNPs. In this perspective, there is an immediate need to develop ecofriendly and biocompatible techniques, which strengthen efficacy against microbes and minimize toxicity for human cells. The present study introduces the biological synthesis of silver nanoparticles, and their potential biomedical applications have also been reviewed.


Processes ◽  
2020 ◽  
Vol 8 (8) ◽  
pp. 998
Author(s):  
Kartini Kartini ◽  
Amarisa Alviani ◽  
Dia Anjarwati ◽  
Adinda Finna Fanany ◽  
Johan Sukweenadhi ◽  
...  

Silver nanoparticles (AgNPs) are an interesting metal nanoparticle that can be incorporated into pharmaceutical products, including for diabetic foot ulcers as an antimicrobial agent. Green synthesis of AgNPs using plant extracts has been drawing much attention as it is simple, eco-friendly, stable, and cost-effective. This present study was performed to evaluate the potential of three Indonesian medicinal plant extracts, namely Phyllanthus niruri (PN), Orthosiphon stamineus (OS), and Curcuma longa (CL), as reducing and capping agents in the green synthesis of AgNPs, and to optimize their concentrations. Based on the yields and characteristics of the formed nanoparticles, which were analyzed using a UV-Vis spectrophotometer, particle size analyzer, scanning electron microscope, and X-ray diffractometer, Phyllanthus niruri extract at a concentration of 0.5% was concluded as the best extract in the green synthesis of AgNPs. It is thereby a prospective reducing and capping agent for further scale-up studies.


2018 ◽  
Vol 46 (sup1) ◽  
pp. 104-114 ◽  
Author(s):  
Murali Satyanarayana Bethu ◽  
Vasudeva Reddy Netala ◽  
Latha Domdi ◽  
Vijaya Tartte ◽  
Venkateswara Rao Janapala

2021 ◽  
pp. 1-14
Author(s):  
Bastian Bergfeld ◽  
Alec van Herwijnen ◽  
Grégoire Bobillier ◽  
Eric Larose ◽  
Ludovic Moreau ◽  
...  

Abstract For the release of a slab avalanche, crack propagation within a weak snowpack layer below a cohesive snow slab is required. As crack speed measurements can give insight into underlying processes, we analysed three crack propagation events that occurred in similar snowpacks and covered all scales relevant for avalanche release. For the largest scale, up to 400 m, we estimated crack speed from an avalanche movie; for scales between 5 and 25 m, we used accelerometers placed on the snow surface and for scales below 5 m, we performed a propagation saw test. The mean crack speeds ranged from 36 ± 6 to 49 ± 5 m s−1, and did not exhibit scale dependence. Using the discrete element method and the material point method, we reproduced the measured crack speeds reasonably well, in particular the terminal crack speed observed at smaller scales. Finally, we used a finite element model to assess the speed of different elastic waves in a layered snowpack. Results suggest that the observed cracks propagated as mixed mode closing cracks and that the flexural wave of the slab is responsible for the energy transfer to the crack tip.


2015 ◽  
Vol 13 (3) ◽  
pp. 359-367
Author(s):  
José J. Ibarra-Sánchez ◽  
Rosalba Fuentes-Ramírez ◽  
José Antonio Reyes-Aguilera ◽  
Susana Figueroa-Gerstenmaier ◽  
Erasmo Orrantia-Borunda ◽  
...  

Abstract In recent years, great efforts have been directed to provide eco-friendly methods for nanoparticles (NPs) synthesis. In this endeavor, it is desired that polydispersity be as narrow as possible and that the chemical and physical properties can be controlled. In this work, silver nanoparticles (SNPs) were obtained by means of (a) a green approach (biosynthesis) using alfalfa extracts; and (b) a thermal decomposition method in organic media. As per biosynthesis, pH, initial concentration of precursor (Ag+) and extraction solvent of plant metabolites were varied in order to identify the conditions where SNP polydispersity presented a best value. When these conditions were determined, the reaction kinetics was evaluated. The rate constant and order of reaction were 7.33×10−6 L3.6/mol3.6 s, and 4.6, respectively. Also, in the biosynthesis, it was found that the size and the degree of polydispersity depend on initial concentration of precursor and the type of extractant. Thermal decomposition was performed using silver oleate as precursor in order to compare characteristics of the NPs obtained by both biosynthesis and the chemical method. According to our results, SNPs obtained through thermal decomposition showed a lower polydispersity and higher degree of crystallinity than those obtained using biosynthesis. However, the green method eliminates the use of toxic compounds, which is extremely important if these particles are intended for biomedical purposes. In addition, this is a less expensive method as compared to other chemical methods. To our knowledge, this is one of the few reports analyzing the reaction kinetics, which is extremely important if scale-up is intended.


2015 ◽  
Vol 2015 ◽  
pp. 1-18 ◽  
Author(s):  
M. Jannathul Firdhouse ◽  
P. Lalitha

Silver nanoparticles possess unique properties which find myriad applications such as antimicrobial, anticancer, larvicidal, catalytic, and wound healing activities. Biogenic syntheses of silver nanoparticles using plants and their pharmacological and other potential applications are gaining momentum owing to its assured rewards. This critical review is aimed at providing an insight into the phytomediated synthesis of silver nanoparticles, its significant applications in various fields, and characterization techniques involved.


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