Anti-hyperlipidemic and Antioxidant Activities of a Combination of Terminalia Arjuna and Commiphora Mukul on Experimental Animals

2020 ◽  
pp. 175-188
Author(s):  
Jhakeshwar Prasad ◽  
Ashish Kumar Netam ◽  
Trilochan Satapathy ◽  
S. Prakash Rao ◽  
Parag Jain
Keyword(s):  
Antioxidant Activities ◽  
Terminalia Arjuna ◽  
Experimental Animals ◽  
Commiphora Mukul

scholarly journals Phytochemical evaluation and antioxidant activities in flower and leaves of Cassia fistula and Terminalia arjuna

2021 ◽  
Vol 2 (2) ◽  
pp. 195-206
Author(s):  
Komal Nawwal ◽  
Amjad Saeed ◽  
Tanveer Hussain ◽  
Sana Ajmal ◽  
Anum Choudry ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Antioxidant Activity ◽  
Biochemical Analysis ◽  
Antioxidant Activities ◽  
Terminalia Arjuna ◽  
Bioactive Components ◽  
Cassia Fistula ◽  
Methanolic Extracts ◽  
The Family ◽  
Natural Remedies

Abstract: The plants Cassia fistula and Terminalia arjuna are medicinally important and produce leaves and colourful blossoms that belong to the Caesalpinioideae of the legume family and the family of Combretaceae. The antioxidant, hydrogen peroxide, and phytochemical assessment (qualitative and quantitative) of methanolic and ethanolic extracts of Cassia fistula and Terminalia arjuna flowers and leaves were investigated in this work. In qualitative phytochemical evaluation, the presence of ten different chemicals of varying degrees and classes was observed, and alkaloids, steroids, tannis, glycosides, saponins, flavonoids, and terpinoids were confirmed during qualitative screening. During quantitative analysis, the Cassia fistula L. leaves showed the highest TFC (32.783A ± 0.073) and the TPC was observed highest in Terminalia arjuna flowers (42.800A ± 0.028). The highest DPPH percentage was recorded in C. fistula flowers (21.825A ± 0.069) compared to its lowest value observed in C. fistula leaves (10.660B ± 0.053). The highest hydrogen peroxide (H2O2) scavenging activity among both plants was found in C. fistula (12.526A ± 0.146) and the lowest in its leaves (7.1470B ± 0.045). The methanolic extracts showed promising antioxidant activity. The presence of bioactive components in the leaves and flowers of Terminalia arjuna and Cassia fistula suggests that these flowers and leaves might be used as a phytochemical source and are also effective and safe as natural remedies. The biochemical analysis proved that the extracts of Cassia fistula and Terminalia arjuna plants have glycosides, flavonoids, and alkaloids that play a role in antioxidant activity.

Hepatoprotective and antioxidant effect of Adiantum lunulatum Burm. F. leaf in alcohol-induced rat model

2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Nimisha Parshottambhai Kakadia ◽  
Monika A Amin ◽  
Shrikalp S Deshpande
Keyword(s):  
Total Bilirubin ◽  
Antioxidant Activities ◽  
Ethanolic Extract ◽  
Hepatoprotective Activity ◽  
Antioxidant Effect ◽  
Serum Enzymes ◽  
Glutamic Oxaloacetic Transaminase ◽  
Serum Glutamic Pyruvic Transaminase ◽  
Serum Glutamic Oxaloacetic Transaminase ◽  
Experimental Animals

ABSTRACTBackgroundAdiantum lunulatum Burm. F. leaf (AL) and its related species have been used traditionally for the treatment of various diseases.ObjectiveThe present study evaluated the hepatoprotective, and antioxidant activities of ethanolic extract of AL.Methodology and ResultThe hepatoprotective effect of AL was evaluated against ethanol-induced hepatotoxicity in rats. Administration of ethanol (2 g/kg) showed a significant biochemical and histological deterioration in the liver of experimental animals. Pretreatment with ethanolic extract of AL (250 and 500 mg/kg b.wt. p.o) significantly reduced the elevated levels of serum enzymes like serum glutamic-oxaloacetic transaminase (AST), serum glutamic-pyruvic transaminase (ALT), alkaline phosphatase (ALP), total protein, total bilirubin and reversed the hepatic damage in the liver which evidenced the hepatoprotective activity. The superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) level notably increased due to doses of AL.ConclusionThe results of the present study demonstrate that the ethanolic extract of AL possesses hepatoprotective and antioxidant activities.Graphical Abstract

Comparative Antioxidant Potential of Bark and Leaves of Terminalia arjuna (Roxb) Wight & Arn from Himachal Pradesh

2017 ◽  
Vol 6 (1) ◽  
pp. 27 ◽  
Author(s):  
Vikas Kumar ◽  
Kamal Dev ◽  
Anuradha Sourirajan ◽  
Prem Kumar Khosla
Keyword(s):  
Antioxidant Activity ◽  
Gallic Acid ◽  
Phenolic Content ◽  
Total Phenolics ◽  
Antioxidant Activities ◽  
Ethanolic Extract ◽  
Terminalia Arjuna ◽  
Total Phenolic ◽  
Flavonoid Content ◽  
Phenolic And Flavonoid

The present study aimed to compare antioxidant activities, total phenolic and flavonoid content present in leaves and bark of Terminalia arjuna and check whether there is any correlation between phenolic content and flavonoid content with antioxidant activities or not. Phytochemical screening of ethanolic extract of leaves and bark revealed the presence of phenols, flavonoids, tannins, carbohydrates, glycosides, saponin, phytosterols and phytosteroids. Total phenolic content was found to be higher in bark (272.71±3.18 mg/g gallic acid equivalents) as compared to that of leaves (95±3.11 mg/g gallic acid equivalents). Similarly, flavonoid content of ethanolic extract of bark was found to be higher (203.95±5.13 mg/g rutin equivalents) than that of leaves (87.625±4.28 mg/g rutin equivalents). DPPH activity of ethanolic extract of bark (IC50-17.41 µg/ml) was more than that of leaves (IC50-20.22µg/ml). FRAP activity of bark (IC50- 4.781 µM Fe (II) equivalents) is more than that of leaves (IC50-7.572 µM Fe (II) equivalents). Nitric oxide (NO) scavenging activity of bark (IC50-12.87 µg/ml) was higher than that of leaves (IC50-13.91 µg/ml).The present study clearly showed that there is a correlation between total phenolics, flavonoid contents and antioxidant activity of leaves and bark of T. arjuna. The phenolic compounds and flavonoids could be major contributor to antioxidant activity of T. arjuna. Keywords: Terminalia arjuna, DPPH, FRAP, NO, IC50, Antioxidants

Antihyperglycemic and antioxidant activities of alcoholic extract of Commiphora mukul gum resin in streptozotocin induced diabetic rats

2011 ◽  
Vol 18 (4) ◽  
pp. 255-261 ◽  
Author(s):  
Ramesh Bellamkonda ◽  
Karuna Rasineni ◽  
Sreenivasa Reddy Singareddy ◽  
Ramesh Babu Kasetti ◽  
Ramatholisamma Pasurla ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Diabetic Rats ◽  
Alcoholic Extract ◽  
Commiphora Mukul

scholarly journals Standardization of leaf age for radical scavenging activity in Terminalia arjuna

2014 ◽  
Vol 6 (1) ◽  
pp. 76-80
Author(s):  
Ranjan P. Kuvad ◽  
Kiran S. Chudasama ◽  
Vibhuti M. Jhala ◽  
Vrinda S. Thaker
Keyword(s):  
Phenolic Compounds ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Leaf Age ◽  
Radical Scavenging ◽  
Botanical Garden ◽  
Terminalia Arjuna ◽  
Scavenging Activity ◽  
Stable Free Radical ◽  
Chromatography Analysis

Terminalia arjuna is one of the many such plant that used in indigenous system of medicine for curing different diseases. For effective formulation of herbal drug selection of proper age of the plant is imperative. In the present study, the T. arjuna plant (leaves) was collected from the Botanical garden of Saurashtra University. The leaves were grouped in to various size and growth analysis was performed. Each extract homogenized in methanol and was used for chlorophyll estimation and antioxidant activities. Radical scavenging activity of the methanol extract of different stages leaves were determined using a stable free radical 2, 2-diphenyl-1-picryl hydrazyl (DPPH), using Micro plate assay. Further the phenolic compounds were separated by Reverse phase high pressure liquid chromatography analysis (RP-HPLC). At the leaf stage when maximum antioxidant activity was observed, phenol like Gallic acid showed distinct peak. The role of phenolic compounds in antioxidant activities is discussed.

Analytical Electron Microscopy (AEM) of Meningeal Cells Exposed to Particulate Cobalt During Studies of Experimental Epilepsy

1982 ◽  
Vol 40 ◽  
pp. 186-187
Author(s):  
R.G. Frederickson ◽  
R.G. Ulrich ◽  
J.L. Culberson
Keyword(s):  
Electron Microscopy ◽  
Analytical Electron Microscopy ◽  
Experimental Epilepsy ◽  
Metallic Cobalt ◽  
Experimental Animals ◽  
X Ray ◽  
Brain Surface ◽  
Meningeal Cells ◽  
Analytical Electron ◽  
The Brain

Metallic cobalt acts as an epileptogenic agent when placed on the brain surface of some experimental animals. The mechanism by which this substance produces abnormal neuronal discharge is unknown. One potentially useful approach to this problem is to study the cellular and extracellular distribution of elemental cobalt in the meninges and adjacent cerebral cortex. Since it is possible to demonstrate the morphological localization and distribution of heavy metals, such as cobalt, by correlative x-ray analysis and electron microscopy (i.e., by AEM), we are using AEM to locate and identify elemental cobalt in phagocytic meningeal cells of young 80-day postnatal opossums following a subdural injection of cobalt particles.

Ultrastructure and analytical microprobe analysis of simian lung mite pigments

1986 ◽  
Vol 44 ◽  
pp. 324-325
Author(s):  
R. W. Cole ◽  
J. C. Kim
Keyword(s):  
Biomedical Research ◽  
Tissue Damage ◽  
Microprobe Analysis ◽  
Old World Monkeys ◽  
Old World ◽  
Experimental Animals ◽  
The Past ◽  
Lung Mite ◽  
Mite Infestations ◽  
Cardiopulmonary System

In recent years, non-human primates have become indispensable as experimental animals in many fields of biomedical research. Pharmaceutical and related industries alone use about 2000,000 primates a year. Respiratory mite infestations in lungs of old world monkeys are of particular concern because the resulting tissue damage can directly effect experimental results, especially in those studies involving the cardiopulmonary system. There has been increasing documentation of primate parasitology in the past twenty years.

The Effect of ACTH on Gastric Secretion in Experimental Animals

1952 ◽  
Vol 21 (2) ◽  
pp. 276-279 ◽  
Author(s):  
Jose M. Zubiran ◽  
Allan E. Kark ◽  
Lester R. Dragstedt
Keyword(s):  
Gastric Secretion ◽  
Experimental Animals
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