Phenolic Compound Contents of Hypericum Species from Turkey

2020 ◽  
pp. 43-68
Author(s):  
Hilal Surmuş Asan
Keyword(s):  
Phenolic Compound ◽  
Hypericum Species

In vitro cytotoxic and antioxidant activity of some Hypericum species belonging to drosanthe section

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
E Eroğlu Özkan ◽  
N Özsoy ◽  
G Özhan ◽  
A Mat
Keyword(s):  
Antioxidant Activity ◽  
Hypericum Species

HPLC Screening of Bioactives Compounds and Antioxidant Capacity of Different Hypericum Species

2018 ◽  
Vol 69 (2) ◽  
pp. 305-309 ◽  
Author(s):  
Daniela Gitea ◽  
Simona Vicas ◽  
Manuel Alexandru Gitea ◽  
Sebastian Nemeth ◽  
Delia Mirela Tit ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Methanol Extract ◽  
Antioxidant Properties ◽  
Polyphenolic Compounds ◽  
The Other ◽  
The North ◽  
Western Area ◽  
North Western ◽  
Hypericum Species ◽  
Biological Actions

Our study compares the content in polyphenolic compounds and hypericin, in four species of Hypericum - H. perforatum L., H. maculatum Cr., H. hirsutum L., H. tetrapterum Fr. (syn. Hypericumacutum Mnch.) harvested from spontaneous flora in the north-western area of Transylvania, Romania. These species represent an important source of such compounds with different biological actions. After making the extracts, they were subjected to HPLC-SM analysis. The presence of rutoside in the largest amount (462.82 mg %) in the H. perforatum extract was observed, this containing most of the flavonoid heterosides. For the species H. maculatum, the presence in a much higher amount of the hyperoside (976.36 mg %) is characteristic compared to the other species. Quercetol is the best represented of the flavonoid aglycons, its concentration being the highest in H. hirsutum (659.66 mg %). The hypericin content ranges from 0.2171 g % in the H. tetrapterum extract, to 0.0314 g % in the methanol extract of H. maculatum.The highest antioxidant properties measured by FRAP method were recorded in the case of H. perforatum and H. maculatum.

Study of the phenolic compound profile and antioxidant activity of human milk from Spanish women at different stages of lactation: A comparison with infant formulas

2021 ◽  
Vol 141 ◽  
pp. 110149
Author(s):  
Silvia Sánchez-Hernández ◽  
Adelaida Esteban-Muñoz ◽  
Cristina Samaniego-Sánchez ◽  
Rafael Giménez-Martínez ◽  
Beatriz Miralles ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Human Milk ◽  
Phenolic Compound ◽  
Infant Formulas ◽  
Spanish Women

scholarly journals Cytotoxic and antigenotoxic properties of phenolic compound isolated from the fruit of Terminalia chebula on HeLa cell

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
K. Soumya ◽  
Jesna James ◽  
T. M. Archana ◽  
A. T. Dhanya ◽  
A. P. Shahid ◽  
...  
Keyword(s):  
Dna Damage ◽  
Gallic Acid ◽  
Phenolic Compound ◽  
Diethyl Ether ◽  
Hela Cells ◽  
Protective Role ◽  
Terminalia Chebula ◽  
Diethyl Ether Extract ◽  
Toxic Concentration ◽  
Isolated Compound

Abstract Background DNA in a human cell is subjected to constant assault from both environmental factors and normal metabolic processes. Accumulation of DNA damage drives the progression of many health disorders like aging, cancer, diabetes, and neurodegenerative disorders. Results The present study focuses on the isolation of phenolic compound from the fruit of Terminalia chebula and its protective role on induced DNA damage. Diethyl ether and ethyl acetate extract of Terminalia chebula fruit were subjected to column chromatographic purification, and the fractions obtained were tested for the presence of phenolics. Fraction-12 isolated from diethyl ether extract was identified as gallic acid, which is used for cytotoxic and DNA damage protection activity assays. To select a non-toxic concentration of isolated compound, cytotoxicity was assessed by MTT assay. Gallic acid showed moderate toxicity at the highest concentration tested (i.e., percentage cell viability at 100 μg/ml is 40.51 ± 1.31). Antigenotoxic effect of gallic acid on HeLa cells was carried by alkaline comet assay. The compound showed significant protective abilities against hydrogen peroxide-induced DNA damage in HeLa cells. Conclusion These results show the importance of gallic acid isolated from Terminalia chebula fruit, as protector of oxidative stress-induced DNA damage.

Tyrosol, a phenolic compound from Phomopsis sp., is a potential biostimulant in soybean seed treatment

2021 ◽  
Vol 43 ◽  
pp. 40-44
Author(s):  
Geraldo Humberto Silva ◽  
Josiane Abadia Resende de Souza ◽  
Willian Rodrigues Macedo ◽  
Frederico Garcia Pinto
Keyword(s):  
Phenolic Compound ◽  
Seed Treatment ◽  
Soybean Seed

scholarly journals Hydroxytyrosol alleviates oxidative stress, neuroinflammation and enhances hippocampal neurotropic signaling to improve stress-induced depressive behaviors in mice

2021 ◽  
Author(s):  
Yun- Tao Zhao ◽  
lu lu zhang ◽  
Haowen Yin ◽  
Ling Shen ◽  
Wenjing Zheng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Phenolic Compound ◽  
Physiological Functions ◽  
Anti Inflammatory

Hydroxytyrosol (HT), the main phenolic compound in olives and olive products, has antioxidative, anti-inflammatory, neuroprotective, and other physiological functions. The effects of HT on depression are unclear. The aim of...

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