Sex pheromone communication in the lepidoptera: New research progress

1989 ◽  
Vol 45 (3) ◽  
pp. 248-262 ◽  
Author(s):  
T. C. Baker
Keyword(s):  
Sex Pheromone ◽  
Research Progress ◽  
Pheromone Communication ◽  
New Research

scholarly journals Advances in the role of miRNAs in the occurrence and development of osteosarcoma

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 1003-1011
Author(s):  
Guanyu Zhang ◽  
Yiran Li ◽  
Jiasheng Xu ◽  
Zhenfang Xiong
Keyword(s):  
Target Gene ◽  
Early Stage ◽  
Research Direction ◽  
Research Progress ◽  
Skeletal System ◽  
Translation Process ◽  
Non Coding Rnas ◽  
New Research ◽  
Post Transcriptional Regulation

AbstractOsteosarcoma (OS) is the most common primary malignant tumor of the skeletal system in the clinic. It mainly occurs in adolescent patients and the pathogenesis of the disease is very complicated. The distant metastasis may occur in the early stage, and the prognosis is poor. MicroRNAs (miRNAs) are non-coding RNAs of about 18–25 nt in length that are involved in post-transcriptional regulation of genes. miRNAs can regulate target gene expression by promoting the degradation of target mRNAs or inhibiting the translation process, thereby the proliferation of OS cells can be inhibited and the apoptosis can be promoted; in this way, miRNAs can affect the metabolism of OS cells and can also participate in the occurrence, invasion, metastasis, and recurrence of OS. Some miRNAs have already been found to be closely related to the prognosis of patients with OS. Unlike other reviews, this review summarizes the miRNA molecules closely related to the development, diagnosis, prognosis, and treatment of OS in recent years. The expression and influence of miRNA molecule on OS were discussed in detail, and the related research progress was summarized to provide a new research direction for early diagnosis and treatment of OS.

MicroRNAs in the pathogenesis of type 2 diabetes: new research progress and future direction

2018 ◽  
Vol 96 (2) ◽  
pp. 103-112 ◽  
Author(s):  
Chenggui Miao ◽  
Guoxue Zhang ◽  
Zhongwen Xie ◽  
Jun Chang
Keyword(s):  
Cell Metabolism ◽  
Age Groups ◽  
Research Progress ◽  
Transcriptional Level ◽  
Physiological Processes ◽  
Non Coding Rna ◽  
Elevated Glucose ◽  
Modulation Of Gene Expression ◽  
Future Direction ◽  
New Research

miRNA is a short non-coding RNA that can influence mRNA processing at the post-transcriptional level. A large number of miRNAs have been found in virtually all species so far, and these small molecules play an important role in many different physiological processes and various pathologic conditions, such as cell metabolism, cancer, autoimmune disease, and diabetes mellitus. T2D arises from a dysregulated response to the elevated glucose level in the circulation. The prevalence of T2D has increased dramatically in all age groups, and T2D in older adults is associated with more T2D complications and higher mortality. Despite the existing findings describing the pathological mechanism, T2D pathology is more complex and the pathophysiology of the disease is still not fully elucidated. In this review, we summarize the current understanding of miRNA-mediated modulation of gene expression in T2D pathogenesis, as well as related signaling pathways, and insight into the important role of miRNA in various T2D complications. Furthermore, the potential therapeutic value of miRNA for T2D patients is also discussed in detail.

scholarly journals Dry root rot of chickpea: A disease favored by drought

Plant Disease ◽  
2021 ◽  
Author(s):  
Avanish Rai ◽  
Vadivelmurugan Irulappan ◽  
Muthappa Senthil-Kumar
Keyword(s):  
Root Rot ◽  
Management Practices ◽  
Lateral Roots ◽  
Research Priorities ◽  
Macrophomina Phaseolina ◽  
Emerging Diseases ◽  
Research Progress ◽  
Initial Symptoms ◽  
New Research ◽  
The Impact

Chickpea is an essential crop for protein nutrition and is grown around the world in rain-fed conditions. However, chickpea cultivation is under threat due to emerging diseases favored by drought stress. Dry root rot (DRR), an economically devastating disease, is an example. Chickpea-specific strains of a necrotic fungal phytopathogen, Macrophomina phaseolina, cause DRR. Microsclerotia of this fungus, which are capable of withstanding harsh environmental conditions, serve as primary inoculum. Initial symptoms are scattered necrotic spots in roots, progressing to rotting and withering lateral roots, accompanied by prematurely dried, straw-colored foliage. The recent rise in global temperature and worsening of drought spells have aggravated DRR outbreaks in chickpea. To date, DRR epidemiology has not been clarified in detail. Also, the literature lacks clarity on M. phaseolina taxonomy, morphology, disease progression, and diagnosis. In this article, research progress on patterns of DRR occurrence in the field and belowground and above-ground symptoms are clarified. In addition, the current understanding of taxonomy and management practices is elaborated. We also summarize knowledge of the impact of drought and high temperature on DRR severity. Further, we provide future perspectives on the importance of host resistance, QTL identification, genotype screening for the identification of resistant genotypes. The article proposes new research priorities and a corresponding plan for the mitigation of DRR.

scholarly journals Defining research priorities in dystonia

Neurology ◽  
2020 ◽  
Vol 94 (12) ◽  
pp. 526-537 ◽  
Author(s):  
Codrin Lungu ◽  
Laurie Ozelius ◽  
David Standaert ◽  
Mark Hallett ◽  
Beth-Anne Sieber ◽  
...  
Keyword(s):  
Research Priorities ◽  
Large Data ◽  
Therapeutic Interventions ◽  
Research Progress ◽  
Data Sets ◽  
Cellular Mechanisms ◽  
Research Technology ◽  
Current State ◽  
History Of ◽  
New Research

ObjectiveDystonia is a complex movement disorder. Research progress has been difficult, particularly in developing widely effective therapies. This is a review of the current state of knowledge, research gaps, and proposed research priorities.MethodsThe NIH convened leaders in the field for a 2-day workshop. The participants addressed the natural history of the disease, the underlying etiology, the pathophysiology, relevant research technologies, research resources, and therapeutic approaches and attempted to prioritize dystonia research recommendations.ResultsThe heterogeneity of dystonia poses challenges to research and therapy development. Much can be learned from specific genetic subtypes, and the disorder can be conceptualized along clinical, etiology, and pathophysiology axes. Advances in research technology and pooled resources can accelerate progress. Although etiologically based therapies would be optimal, a focus on circuit abnormalities can provide a convergent common target for symptomatic therapies across dystonia subtypes. The discussions have been integrated into a comprehensive review of all aspects of dystonia.ConclusionOverall research priorities include the generation and integration of high-quality phenotypic and genotypic data, reproducing key features in cellular and animal models, both of basic cellular mechanisms and phenotypes, leveraging new research technologies, and targeting circuit-level dysfunction with therapeutic interventions. Collaboration is necessary both for collection of large data sets and integration of different research methods.

scholarly journals A Review on the Mechanism, Impacts and Control Methods of Membrane Fouling in MBR System

Membranes ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 24 ◽  
Author(s):  
Xianjun Du ◽  
Yaoke Shi ◽  
Veeriah Jegatheesan ◽  
Izaz Ul Haq
Keyword(s):  
Membrane Fouling ◽  
Life Prediction ◽  
Research Progress ◽  
Relevant Research ◽  
Effluent Quality ◽  
Research Areas ◽  
Residual Sludge ◽  
Mechanism Control ◽  
New Research ◽  
And Control

Compared with the traditional activated sludge process, a membrane bioreactor (MBR) has many advantages, such as good effluent quality, small floor space, low residual sludge yield and easy automatic control. It has a promising prospect in wastewater treatment and reuse. However, membrane fouling is the biggest obstacle to the wide application of MBR. This paper aims at summarizing the new research progress of membrane fouling mechanism, control, prediction and detection in the MBR systems. Classification, mechanism, influencing factors and control of membrane fouling, membrane life prediction and online monitoring of membrane fouling are discussed. The research trends of relevant research areas in MBR membrane fouling are prospected.

scholarly journals Research Progress on Interlaminar Failure Behavior of Fiber Metal Laminates

2020 ◽  
Vol 2020 ◽  
pp. 1-20
Author(s):  
Yizhe Chen ◽  
Yichun Wang ◽  
Hui Wang
Keyword(s):  
Mechanical Properties ◽  
Failure Modes ◽  
Control Method ◽  
Research Progress ◽  
Failure Behavior ◽  
Control Methods ◽  
Fiber Metal Laminate ◽  
Fiber Metal ◽  
Structural Parts ◽  
New Research

Fiber metal laminate (FML) is a kind of lightweight material with excellent mechanical properties combining advantages of metal laminates and fiber reinforced composites. It has been widely used in the aerospace and transportation fields and is especially used as structural material such as aircraft skins, wings, and tails. However, under complex service conditions, interlaminar failure in FMLs greatly reduced mechanical properties of the material, even leading to serious economic and safety disasters. The failure and destruction of important structural parts of aircraft and other manned transportation vehicles are extremely unsafe for people. Therefore, it is of great significance to summarize the interlaminar failure behavior of FMLs and find ways to avoid these defects. This review paper is a collection of various researches done by many groups, which systematically discuss the interlaminar failure behaviors and their control methods of FMLs. The application status of several common FMLs in aircraft structures was given. The common interlaminar failure modes of FMLs and the testing and evaluation methods of interlaminar properties were stated. The failure mechanisms and the corresponding control methods were analyzed. Finally, the future developments of FMLs were also discussed by the authors. Through this review article, readers can obtain new research progress about the control method, the mechanism and future development on the failure behavior of FMLs in a more efficient way.

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