Molecular species composition of phosphatidylcholines during the development of the avian embryo brain

Lipids ◽  
1980 ◽  
Vol 15 (5) ◽  
pp. 279-284 ◽  
Author(s):  
Jose M. Gonzalez-Ros ◽  
A. Ribera
2002 ◽  
Vol 77 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Changhu Xue ◽  
Yaqin Hu ◽  
Hiroaki Saito ◽  
Zhaohui Zhang ◽  
Zhaojie Li ◽  
...  

2005 ◽  
Vol 33 (5) ◽  
pp. 1146-1149 ◽  
Author(s):  
H.A. Boumann ◽  
A.I.P.M. de Kroon

Phosphatidylcholine (PC) is a very abundant membrane lipid in most eukaryotes, including yeast. The molecular species profile of PC, i.e. the ensemble of PC molecules with acyl chains differing in number of carbon atoms and double bonds, is important for membrane function. Pathways of PC synthesis and turnover maintain PC homoeostasis and determine the molecular species profile of PC. Studies addressing the processes involved in establishing the molecular species composition of PC in yeast using stable isotope labelling combined with detection by MS are reviewed.


Parasitology ◽  
1993 ◽  
Vol 107 (5) ◽  
pp. 465-469
Author(s):  
S. Fiebig ◽  
A. P. Simões ◽  
F. Wunderlich ◽  
J. A. F. Op Den Kamp

SUMMARYThis study is concerned with the influence of testosterone on the phospholipid class and the phosphatidylcholine molecular species composition of various fractions obtained from the blood of Plasmodium chabaudi-infected mice. Blood plasma, infected erythrocytes, isolated parasites and erythrocyte membranes isolated from both non-infected and infected erythrocytes in the form of ghosts were analysed. In general, the phospholipid classes remained unaffected, while the phosphatidylcholine (PC) molecular species composition showed differences after testosterone treatment. In infected erythrocytes, there was a decrease in 16:0/20:4-PC and 18:0/20:4-PC and an increase in 16:0/18:2(16:0/20:3)-PC. The decrease of 16:0/20:4-PC was exclusively confined to parasites. The rise in 16:0/18:2(16:0/20: 3)-PC and the diminution of 18:0/20:4-PC occurred in the erythrocyte membrane of both infected ghosts and non-infected ghosts as well as in the blood plasma. It is suggested that these changes occur primarily in the plasma thereby influencing the erythrocyte membranes. The decrease in 16:0/20:4-PC supports the view of the independence of the parasite from the biosynthetic lipid pathways of its host cell.


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