Effects of conjugated linoleic acid on body fat accumulation and serum lipids in hamsters fed an atherogenic diet

2003 ◽  
Vol 59 (3) ◽  
pp. 193-199 ◽  
Author(s):  
V. Navarro ◽  
A. Zabala ◽  
M. T. Macarulla ◽  
A. Fernández-Quintela ◽  
V. M. Rodríguez ◽  
...  
1999 ◽  
Vol 276 (4) ◽  
pp. R1172-R1179 ◽  
Author(s):  
James P. DeLany ◽  
Fawn Blohm ◽  
Alycia A. Truett ◽  
Joseph A. Scimeca ◽  
David B. West

Recent reports have demonstrated that conjugated linoleic acid (CLA) has effects on body fat accumulation. In our previous work, CLA reduced body fat accumulation in mice fed either a high-fat or low-fat diet. Although CLA feeding reduced energy intake, the results suggested that some of the metabolic effects were not a consequence of the reduced food intake. We therefore undertook a study to determine a dose of CLA that would have effects on body composition without affecting energy intake. Five doses of CLA (0.0, 0.25, 0.50, 0.75, and 1.0% by weight) were studied in AKR/J male mice ( n = 12/group; age, 39 days) maintained on a high-fat diet (%fat 45 kcal). Energy intake was not suppressed by any CLA dose. Body fat was significantly lower in the 0.50, 0.75, and 1.0% CLA groups compared with controls. The retroperitoneal depot was most sensitive to the effects of CLA, whereas the epididymal depot was relatively resistant. Higher doses of CLA also significantly increased carcass protein content. A time-course study of the effects of 1% CLA on body composition showed reductions in fat pad weights within 2 wk and continued throughout 12 wk of CLA feeding. In conclusion, CLA feeding produces a rapid, marked decrease in fat accumulation, and an increase in protein accumulation, at relatively low doses without any major effects on food intake.


2006 ◽  
Vol 62 (2) ◽  
pp. 81-87 ◽  
Author(s):  
V. Navarro ◽  
J. Miranda ◽  
I. Churruca ◽  
A. Fernández-Quintela ◽  
V. M. Rodríguez ◽  
...  

2001 ◽  
Vol 65 (10) ◽  
pp. 2200-2204 ◽  
Author(s):  
Koichiro OHNUKI ◽  
Satoshi HARAMIZU ◽  
Kengo ISHIHARA ◽  
Tohru FUSHIKI

2009 ◽  
Vol 102 (11) ◽  
pp. 1583 ◽  
Author(s):  
Jonatan Miranda ◽  
Itziar Churruca ◽  
Alfredo Fernández-Quintela ◽  
Victor Manuel Rodríguez ◽  
María Teresa Macarulla ◽  
...  

2001 ◽  
Vol 12 (10) ◽  
pp. 585-594 ◽  
Author(s):  
Vassilis Mougios ◽  
Antonis Matsakas ◽  
Anatoli Petridou ◽  
Susanne Ring ◽  
Angelos Sagredos ◽  
...  

Nutrition ◽  
2001 ◽  
Vol 17 (5) ◽  
pp. 385-390 ◽  
Author(s):  
Shaikh Mizanoor Rahman ◽  
Yu-Ming Wang ◽  
Hiroaki Yotsumoto ◽  
Jae-Young Cha ◽  
Seo-Young Han ◽  
...  

2012 ◽  
Vol 15 (4) ◽  
pp. 406-412 ◽  
Author(s):  
Jocelem Mastrodi Salgado ◽  
Tânia Rachel Baroni Ferreira ◽  
Carlos M. Donado-Pestana ◽  
Omer Cavalcanti de Almeida ◽  
Aline Mouro Ribeiro das Neves ◽  
...  

2007 ◽  
Vol 72 (8) ◽  
pp. S612-S617 ◽  
Author(s):  
Y. Park ◽  
K.J. Albright ◽  
J.M. Storkson ◽  
W. Liu ◽  
M.W. Pariza

2010 ◽  
Vol 140 (11) ◽  
pp. 1949-1955 ◽  
Author(s):  
Liam A. Sinclair ◽  
Weerasinghe M. P. B. Weerasinghe ◽  
Robert G. Wilkinson ◽  
Michael J. de Veth ◽  
Dale E. Bauman

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