scholarly journals Topology optimization of three dimensional tissue engineering scaffold architectures for prescribed bulk modulus and diffusivity

2010 ◽  
Vol 42 (4) ◽  
pp. 633-644 ◽  
Author(s):  
Heesuk Kang ◽  
Chia-Ying Lin ◽  
Scott J. Hollister
Keyword(s):  
Tissue Engineering ◽  
Topology Optimization ◽  
Bulk Modulus ◽  
Three Dimensional ◽  
Tissue Engineering Scaffold

Three dimensional spongy fibroin scaffolds containing keratin/vanillin particles as an antibacterial skin tissue engineering scaffold

2020 ◽  
pp. 1-12
Author(s):  
Abdollah Zakeri-Siavashani ◽  
Mohsen Chamanara ◽  
Ehsan Nassireslami ◽  
Mahdi Shiri ◽  
Mohsen Hoseini-Ahmadabadi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Three Dimensional ◽  
Tissue Engineering Scaffold ◽  
Skin Tissue ◽  
Skin Tissue Engineering

Comparison on the Osteogenesis Potential between Poly(lactide-Co-Glycolide) and Alginate as Bone Tissue Engineering Scaffold In Vivo

2007 ◽  
Vol 330-332 ◽  
pp. 1173-1176 ◽  
Author(s):  
Cai Li ◽  
Run Liang Chen ◽  
Lei Liu ◽  
Yun Feng Lin ◽  
Wei Dong Tian ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Three Dimensional ◽  
Tissue Engineering Scaffold ◽  
Autogenous Bone ◽  
Mechanical Characters

Poly(lactide-co-glycolide) (PLGA) and alginate(AG) are the most promising scaffolds in the bone tissue engineering for their stable mechanical characters and three-dimensional porous structure. This study aimed to assay the in vivo osteogenesis potentials by loading the autogenous bone marrow stromal cells (BMSCs) on PLGA or AG. The results suggested that PLGA and AG are both ideal bone tissue engineering scaffold. BMSCs/AG has stronger osteogenesis potentials in vivo than BMSCs/PLGA.

scholarly journals Fabrication of Nanohydroxyapatite/Poly(caprolactone) Composite Microfibers Using Electrospinning Technique for Tissue Engineering Applications

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Mohd Izzat Hassan ◽  
Tao Sun ◽  
Naznin Sultana
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Three Dimensional ◽  
Average Diameter ◽  
Tissue Engineering Scaffold ◽  
Engineering Applications ◽  
Electrospinning Technique ◽  
Fibrous Scaffolds ◽  
Nanosized Hydroxyapatite ◽  
Poly Caprolactone

Tissue engineering fibrous scaffolds serve as three-dimensional (3D) environmental framework by mimicking the extracellular matrix (ECM) for cells to grow. Biodegradable polycaprolactone (PCL) microfibers were fabricated to mimic the ECM as a scaffold with 7.5% (w/v) and 12.5% (w/v) concentrations. Lower PCL concentration of 7.5% (w/v) resulted in microfibers with bead defects. The average diameter of fibers increased at higher voltage and the distance of tip to collector. Further investigation was performed by the incorporation of nanosized hydroxyapatite (nHA) into microfibers. The incorporation of 10% (w/w) nHA with 7.5% (w/v) PCL solution produced submicron sized beadless fibers. The microfibrous scaffolds were evaluated using various techniques. Biodegradable PCL and nHA/PCL could be promising for tissue engineering scaffold application.

Constructing a novel three-dimensional scaffold with mesoporous TiO2 nanotubes for potential bone tissue engineering

2015 ◽  
Vol 3 (27) ◽  
pp. 5595-5602 ◽  
Author(s):  
Yizao Wan ◽  
Peng Chang ◽  
Zhiwei Yang ◽  
Guangyao Xiong ◽  
Ping Liu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bacterial Cellulose ◽  
Bone Tissue ◽  
Tio2 Nanotubes ◽  
Sol Gel ◽  
Three Dimensional ◽  
Mesoporous Tio2 ◽  
Tissue Engineering Scaffold ◽  
Porous Network

A novel 3D porous network-structured tissue engineering scaffold built of mesoporous TiO2 nanotubes has been synthesized via the bacterial cellulose-templated sol–gel route followed by calcination.

3D bioprinting of tissue engineering scaffold for cell culture

2020 ◽  
Vol 26 (5) ◽  
pp. 835-840
Author(s):  
Li Wu ◽  
Xinxin Li ◽  
Tianmin Guan ◽  
Yong Chen ◽  
Chunwei Qi
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Three Dimensional ◽  
Tissue Engineering Scaffold ◽  
Tissue Engineering Scaffolds ◽  
Content Type ◽  
Cell Proliferation And Differentiation ◽  
Proliferation And Differentiation ◽  
Line Spacing ◽  
Microstructural Design

Purpose The 3 D bioprinting technology is used to prepare the tissue engineering scaffold with precise structures for the cell proliferation and differentiation. Design/methodology/approach According to the characteristics of the ideal tissue engineering scaffold, the microstructural design of the tissue engineering scaffold is carried out. The bioprinter is used to fabricate the tissue engineering scaffold with different structures and spacing sizes. Finally, the scaffold with good connectivity is achieved and used to cell PC12 culture. Findings The results show that the pore structure with the line spacing of 1 mm was the best for cell culture, and the survival rate of the inoculated cells PC12 is as high as 90%. The influence of the pore shape on the cell survival is not evidence. Originality/value This study shows that tissue engineering scaffolds prepared by 3 D bioprinting have graded structure for three-dimensional cell culture, which lays the foundation for the later detection of drug resistance.

A Hybrid Three-Dimensional Nanofabrication Method for Producing Vascular Tissue Engineering Scaffold

2008 ◽  
Vol 47 (9) ◽  
pp. 7415-7419 ◽  
Author(s):  
Nikolaj Gadegaard ◽  
Kris Seunarine ◽  
David J. A. Smith ◽  
David O. Meredith ◽  
Chris D. W. Wilkinson ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Three Dimensional ◽  
Tissue Engineering Scaffold ◽  
Vascular Tissue Engineering

Characterization of an Insoluble Collagen Sponge and the Potential for Tissue Engineering Scaffold

2009 ◽  
Vol 610-613 ◽  
pp. 1378-1381 ◽  
Author(s):  
Ling Zhang ◽  
Yan Zhang ◽  
Bo Jiang ◽  
Hong Song Fan ◽  
Xing Dong Zhang
Keyword(s):  
Tissue Engineering ◽  
Three Dimensional ◽  
Collagen Sponge ◽  
Tissue Engineering Scaffold ◽  
Insoluble Collagen ◽  
Acid Soluble Collagen ◽  
Biomedical Field ◽  
Triple Helical Domain

Collagen has been widely used in biomedical field, such as scaffolds for tissue engineering. However, the rapidly biodegradation and weak mechanical strength of collagen limited its application. In this study, an insoluble collagen extracted from cattle hide was designed as scaffold to act as a three-dimensional substrate for tissue engineering. The received insoluble collagen sponge was analyzed by scanning electron microscopy, infrared spectroscopy, mechanical testing and thermogravimetric-differential thermal analysis. In addition, the degradation was performed in vitro using collagenase. The results showed that the insoluble collagen had the same triple helical domain as acid-soluble collagen, while the compression strength was greatly improved and the degradation rate was reduced. The insoluble collagen sponge with good stability should be promising in tissue engineering scaffold applications.

Biocompatabiltiy of Chitosan/Poly(L-Lactic Acid) Composite Scaffolds with Three-Dimensional Honeycomb Patterned Structure

2011 ◽  
Vol 140 ◽  
pp. 29-33
Author(s):  
Ming Yan Zhao ◽  
Li Hua Li ◽  
Guo Dong Sun ◽  
Chang Ren Zhou
Keyword(s):  
Mechanical Property ◽  
Tissue Engineering ◽  
Lactic Acid ◽  
Three Dimensional ◽  
Tissue Engineering Scaffold ◽  
Good Mechanical Property ◽  
Composite Scaffolds ◽  
Ideal Candidate

Three dimensional (3D) scaffolds provide the necessary support for cells to attach, proliferate and differentiate, and define the overall shape of the tissue engineered transplant. In this study, 3D honeycomb patterned chitosan/poly (L-lactic acid) composite scaffolds fabricated by an easy manipulated technique with good mechanical property and cytocompatability, as demonstrated by a previous study. Here we investigated further the in vitro cytocompatibility and spine regeneration in vivo by implanting the construct into male white rabbits for 4 and 8weeks. Results showed that such a honeycomb patterned scaffolds have a good cytocompatibilty. Also, the rabbit spinal defect was perfectly restored. These findings supported that such a 3D honeycomb patterned scaffold is an ideal candidate for the tissue engineering scaffold.

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