scholarly journals Structural failure during extrusion-based 3D printing processes

2019 ◽  
Vol 104 (1-4) ◽  
pp. 565-584 ◽  
Author(s):  
R. J. M. Wolfs ◽  
A. S. J. Suiker
2019 ◽  
Vol 56 (4) ◽  
pp. 801-811
Author(s):  
Mircea Dorin Vasilescu

This work are made for determine the possibility of generating the specific parts of a threaded assembly. If aspects of CAD generating specific elements was analysed over time in several works, the technological aspects of making components by printing processes 3D through optical polymerization process is less studied. Generating the threaded appeared as a necessity for the reconditioning technology or made components of the processing machines. To determine the technological aspects of 3D printing are arranged to achieve specific factors of the technological process, but also from the specific elements of a trapezoidal thread or spiral for translate granular material in supply process are determined experimentally. In the first part analyses the constructive generation process of a spiral element. In the second part are identified the specific aspects that can generation influence on the process of realization by 3D DLP printing of the two studied elements. The third part is affected to printing and determining the dimensions of the analysed components. We will determine the specific value that can influence the process of making them in rapport with printing process. The last part is affected by the conclusions. It can be noticed that both the orientation and the precision of generating solid models have a great influence on the made parts.


Procedia CIRP ◽  
2021 ◽  
Vol 98 ◽  
pp. 348-353
Author(s):  
Rishi Kumar ◽  
Christopher Rogall ◽  
Sebastian Thiede ◽  
Christoph Herrmann ◽  
Kuldip Singh Sangwan

Author(s):  
Getachew Tedla ◽  
Annie M. Jarabek ◽  
Peter Byrley ◽  
William Boyes ◽  
Kim Rogers

2015 ◽  
Vol 137 (08) ◽  
pp. 42-45
Author(s):  
Mike Vasquez

This article reviews the challenges for companies while adopting three-dimensional (3D) printing technology. A big challenge for companies figuring out whether they need to invest in 3-D printing is the different types of printing systems available in the market. At a high level, there are seven different families of 3-D printing processes. Each of the seven technologies is differentiated by the materials used and how the materials are fused together to create three-dimensional objects. Another barrier is that most companies have not yet found it viable to put the processes in place to incorporate the change in design, engineering, and manufacturing production that is required. Not only capital funds are needed to purchase machines, but to effectively use the technology to create a sellable product, one also needs to have a targeted product line and clear vision of the ways that 3-D printing can help lower material costs, save energy, and simplify manufacturing and assembly.


Author(s):  
Rishi Thakkar ◽  
Yu Zhang ◽  
Jiaxiang Zhang ◽  
Mohammed Maniruzzaman

AbstractThis study demonstrated the first case of combining novel continuous granulation with powder-based pharmaceutical 3-dimensional (3D) printing processes to enhance the dissolution rate and physical properties of a poorly water-soluble drug. Powder bed fusion (PBF) and binder jetting 3D printing processes have gained much attention in pharmaceutical dosage form manufacturing in recent times. Although powder bed-based 3D printing platforms have been known to face printing and uniformity problems due to the inherent poor flow properties of the pharmaceutical physical mixtures (feedstock). Moreover, techniques such as binder jetting currently do not provide any solubility benefits to active pharmaceutical ingredients (APIs) with poor aqueous solubility (>40% of marketed drugs). For this study, a hot-melt extrusion-based versatile granulation process equipped with UV-Vis process analytical technology (PAT) tools for the in-line monitoring of critical quality attributes (i.e., solid-state) of indomethacin was developed. The collected granules with enhanced flow properties were mixed with vinylpyrrolidone-vinyl acetate copolymer and a conductive excipient for efficient sintering. These mixtures were further characterized for their bulk properties observing an excellent flow and later subjected to a PBF-3D printing process. The physical mixtures, processed granules, and printed tablets were characterized using conventional as well as advanced solid-state characterization. These characterizations revealed the amorphous nature of the drug in the processed granules and printed tablets. Further, the in vitro release testing of the tablets with produced granules as a reference standard depicted a notable solubility advantage (100% drug released in 5 minutes at >pH 6.8) over the pure drug and the physical mixture. Our developed system known as DosePlus combines innovative continuous granulation and PBF-3D printing process which can potentially improve the physical properties of the bulk drug and formulations in comparison to when used in isolation. This process can further find application in continuous manufacturing of granules and additive manufacturing of pharmaceuticals to produce dosage forms with excellent uniformity and solubility advantage.Abstract Figure


2020 ◽  
Vol 26 (6) ◽  
pp. 1113-1129
Author(s):  
Lai Jiang ◽  
Xiaobo Peng ◽  
Daniel Walczyk

Purpose This paper aims to summarize the up-to-date research performed on combinations of various biofibers and resin systems used in different three-dimensional (3D) printing technologies, including powder-based, material extrusion, solid-sheet and liquid-based systems. Detailed information about each process, including materials used and process design, are described, with the resultant products’ mechanical properties compared with those of 3D-printed parts produced from pure resin or different material combinations. In most processes introduced in this paper, biofibers are beneficial in improving the mechanical properties of 3D-printed parts and the biodegradability of the parts made using these green materials is also greatly improved. However, research on 3D printing of biofiber-reinforced composites is still far from complete, and there are still many further studies and research areas that could be explored in the future. Design/methodology/approach The paper starts with an overview of the current scenario of the composite manufacturing industry and then the problems of advanced composite materials are pointed out, followed by an introduction of biocomposites. The main body of the paper covers literature reviews of recently emerged 3D printing technologies that were applied to biofiber-reinforced composite materials. This part is classified into subsections based on the form of the starting materials used in the 3D printing process. A comprehensive conclusion is drawn at the end of the paper summarizing the findings by the authors. Findings Most of the biofiber-reinforced 3D-printed products exhibited improved mechanical properties than products printed using pure resin, indicating that biofibers are good replacements for synthetic ones. However, synthetic fibers are far from being completely replaced by biofibers due to several of their disadvantages including higher moisture absorbance, lower thermal stability and mechanical properties. Many studies are being performed to solve these problems, yet there are still some 3D printing technologies in which research concerning biofiber-reinforced composite parts is quite limited. This paper unveils potential research directions that would further develop 3D printing in a sustainable manner. Originality/value This paper is a summary of attempts to use biofibers as reinforcements together with different resin systems as the starting material for 3D printing processes, and most of the currently available 3D printing techniques are included herein. All of these attempts are solutions to some principal problems with current 3D printing processes such as the limit in the variety of materials and the poor mechanical performance of 3D printed parts. Various types of biofibers are involved in these studies. This paper unveils potential research directions that would further widen the use of biofibers in 3D printing in a sustainable manner.


Author(s):  
Sahand Hajifar ◽  
Ramanarayanan Purnanandam ◽  
Hongyue Sun ◽  
Chi Zhou

Abstract 3D printing is a promising technique to fabricate flexible parts and reduce the supply chain. Various materials, such as metal powders, plastics, ultraviolet (UV) sensitive resins, can be fabricated from 3D printing and form the final printed part. Currently, most researchers either focus on exploring printable materials with good property or focus on the process quality control given a certain type of material. However, for many 3D printing processes, the printing process and product properties are dependent on both the material properties and process settings. To the best of the authors’ knowledge, the quantitative analysis of the interactions of material properties and printing process settings are rarely studied. In this paper, we treat the material preparation and 3D printing as different manufacturing stages, and we explore the multi-stage effects in 3D printing. In particular, we add carbon fiber to the CLEAR resin to alter the material properties for a stereolithography (SLA) 3D printing process. It is observed that the part properties are jointly affected by material properties and printing process settings. Therefore, the material property and process settings should be jointly considered for optimizing 3D printing processes.


Pharmaceutics ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 124 ◽  
Author(s):  
Mohammad A. Azad ◽  
Deborah Olawuni ◽  
Georgia Kimbell ◽  
Abu Zayed Md Badruddoza ◽  
Md. Shahadat Hossain ◽  
...  

Three dimensional (3D) printing as an advanced manufacturing technology is progressing to be established in the pharmaceutical industry to overcome the traditional manufacturing regime of 'one size fits for all'. Using 3D printing, it is possible to design and develop complex dosage forms that can be suitable for tuning drug release. Polymers are the key materials that are necessary for 3D printing. Among all 3D printing processes, extrusion-based (both fused deposition modeling (FDM) and pressure-assisted microsyringe (PAM)) 3D printing is well researched for pharmaceutical manufacturing. It is important to understand which polymers are suitable for extrusion-based 3D printing of pharmaceuticals and how their properties, as well as the behavior of polymer–active pharmaceutical ingredient (API) combinations, impact the printing process. Especially, understanding the rheology of the polymer and API–polymer mixtures is necessary for successful 3D printing of dosage forms or printed structures. This review has summarized a holistic materials–process perspective for polymers on extrusion-based 3D printing. The main focus herein will be both FDM and PAM 3D printing processes. It elaborates the discussion on the comparison of 3D printing with the traditional direct compression process, the necessity of rheology, and the characterization techniques required for the printed structure, drug, and excipients. The current technological challenges, regulatory aspects, and the direction toward which the technology is moving, especially for personalized pharmaceuticals and multi-drug printing, are also briefly discussed.


2020 ◽  
Vol 28 (5) ◽  
pp. 1345-1367 ◽  
Author(s):  
Alina Ghilan ◽  
Aurica P. Chiriac ◽  
Loredana E. Nita ◽  
Alina G. Rusu ◽  
Iordana Neamtu ◽  
...  

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