Peripheral quantitative computed tomography (pQCT)–based finite element analysis provides enhanced diagnostic performance in identifying non-vertebral fracture patients compared with dual-energy X-ray absorptiometry

2019 ◽  
Vol 31 (1) ◽  
pp. 141-151 ◽  
Author(s):  
H. Jiang ◽  
D.L. Robinson ◽  
C.J. Yates ◽  
P.V.S. Lee ◽  
J.D. Wark
2017 ◽  
Vol 60 (No. 12) ◽  
pp. 682-690
Author(s):  
A. Charuta ◽  
MR Tatara ◽  
M. Dzierzecka ◽  
E. Polawska ◽  
I. Ptaszynska-Sarosiek

The aim of this study was to evaluate interrelationships of body weight and bone weight and densitometric properties of the tibiotarsus in White Koluda Geese (W31) in the post-hatching period. The study was performed using dual-energy X-ray absorptiometry (DEXA) and peripheral quantitative computed tomography (pQCT) at two different parts of tibia: proximal metaphysis and mid-diaphysis. The investigation was performed on 100 bones obtained from males and females at the age of 1, 14, 28, 42 and 56 days of life. All the calculations were performed using the Statistica 9.0 software (StatSoft, Inc. Tulsa, USA). Pearson’s correlation coefficient of body weight and bone weight with all the investigated variables of bone was determined. Depending on the method used for densitometric measurements – DEXA or pQCT, the current study has revealed significant differences in the number of correlations of bone weight and body weight with the evaluated densitometric parameters. Sex-related differences in the investigated interrelationships were also found. In the case of proximal epiphysis, negative correlations of vBMD, tBMC, CTR_DEN and CRT_CNT with body weight and bone weight dominated in one-day-old males. Based on the current observations and the negative correlations of body weight and vBMD, CRT_DEN and TRAB_DEN obtained in the mid-diaphysis of tibiotarsus at the age of 14 days of life, it was concluded that this bone is much more prone to deformations and fractures in males than in females.


2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Meng Zhang ◽  
Jiazi Gao ◽  
Xu Huang ◽  
He Gong ◽  
Min Zhang ◽  
...  

Quantitative computed tomography-based finite element analysis (QCT/FEA) has been developed to predict vertebral strength. However, QCT/FEA models may be different with scan resolutions and element sizes. The aim of this study was to explore the effects of scan resolutions and element sizes on QCT/FEA outcomes. Nine bovine vertebral bodies were scanned using the clinical CT scanner and reconstructed from datasets with the two-slice thickness, that is, 0.6 mm (PA resolution) and 1 mm (PB resolution). There were significantly linear correlations between the predicted and measured principal strains (R2>0.7, P<0.0001), and the predicted vertebral strength and stiffness were modestly correlated with the experimental values (R2>0.6, P<0.05). Two different resolutions and six different element sizes were combined in pairs, and finite element (FE) models of bovine vertebral cancellous bones in the 12 cases were obtained. It showed that the mechanical parameters of FE models with the PB resolution were similar to those with the PA resolution. The computational accuracy of FE models with the element sizes of 0.41 × 0.41 × 0.6 mm3 and 0.41 × 0.41 × 1 mm3 was higher by comparing the apparent elastic modulus and yield strength. Therefore, scan resolution and element size should be chosen optimally to improve the accuracy of QCT/FEA.


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