scholarly journals Analysis of primary metabolites of Morchella fruit bodies and mycelium based on widely targeted metabolomics

2021 ◽  
Vol 204 (1) ◽  
Author(s):  
Yuhong Yang ◽  
Jian Yang ◽  
Hongling Wang ◽  
Yusong Jin ◽  
Jing Liu ◽  
...  
Keyword(s):  
Targeted Metabolomics ◽  
Primary Metabolites ◽  
Widely Targeted Metabolomics

scholarly journals Analysis of Primary Metabolites of Morchella Fruit Bodies And Mycelium Based On Widely Targeted Metabolomics

2021 ◽  
Author(s):  
Yuhong Yang ◽  
Jian Yang ◽  
Hongling Wang ◽  
Yusong Jin ◽  
Jing Liu ◽  
...  
Keyword(s):  
Metabolic Pathway ◽  
Metabolic Pathways ◽  
Biosynthetic Pathway ◽  
Biological Activities ◽  
Targeted Metabolomics ◽  
Primary Metabolites ◽  
Synthetic Pathway ◽  
Effective Components ◽  
Widely Targeted Metabolomics ◽  
Experimental Group

Abstract Morchella is a kind of medicinal and edible homologous fungia that is rich in multiple metabolites. The metabolites from Morchella are a kind of essential substance because of their biological activities. In this study, Morchella fruit bodies and mycelium were selected to identify their metabolites. The primary metabolites of the two experimental group were analyzed using a method of widely targeted metabolome based on UPLC-ESI-MS/MS. A total of 354 different metabolites, including 188 upregulated metabolites and 166 downregulated metabolites, were characterized. Further, the main 20 metabolic pathways of the metabolites were analyzed. The first 9 ones are tyrosine metabolites, thyroid hormone biosynthetic pathway, phenylalanine metabolites, linoleic metabolites synthetic pathway, glycerophosphate metabolic pathway, choline in tumors, methyl butyl metabolites, arginine synthetic pathway, arginine, arginine and proline metabolites. This study provides theoretical basis for the analysis of metabolic pathway of Morchella fruit bodies and mycelium that serving for further research of their medicinal mechanism and effective components.

scholarly journals Extensive Metabolite Profiling in the Unexploited Organs of Black Tiger for Their Potential Valorization in the Pharmaceutical Industry

Life ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 544
Author(s):  
Jianfei Gao ◽  
Kangning Xiong ◽  
Wei Zhou ◽  
Weijie Li
Keyword(s):  
Acid Metabolism ◽  
Metabolite Profile ◽  
Industrial Applications ◽  
Targeted Metabolomics ◽  
Arginine Biosynthesis ◽  
Nutritional Values ◽  
Phenylpropanoid Biosynthesis ◽  
Tyrosine Metabolism ◽  
Organ Specific ◽  
Widely Targeted Metabolomics

Black tiger (Kadsura coccinea (Lem.)) has been reported to hold enormous pharmaceutical potential. The fruit and rhizome of black tiger are highly exploited in the pharmaceutical and other industries. However, the most important organs from the plant such as the leaf and stem are considered biowastes mainly because a comprehensive metabolite profile has not been reported in these organs. Knowledge of the metabolic landscape of the unexploited black tiger organs could help identify and isolate important compounds with pharmaceutical and nutritional values for a better valorization of the species. In this study, we used a widely targeted metabolomics approach to profile the metabolomes of the K. coccinea leaf (KL) and stem (KS) and compared them with the root (KR). We identified 642, 650 and 619 diverse metabolites in KL, KS and KR, respectively. A total of 555 metabolites were mutually detected among the three organs, indicating that the leaf and stem organs may also hold potential for medicinal, nutritional and industrial applications. Most of the differentially accumulated metabolites between organs were enriched in flavone and flavonol biosynthesis, phenylpropanoid biosynthesis, arginine and proline metabolism, arginine biosynthesis, tyrosine metabolism and 2-oxocarboxylic acid metabolism pathways. In addition, several important organ-specific metabolites were detected in K. coccinea. In conclusion, we provide extensive metabolic information to stimulate black tiger leaf and stem valorization in human healthcare and food.

scholarly journals Changes in Metabolome and Nutritional Quality of Lycium barbarum Fruits from Three Typical Growing Areas of China as Revealed by Widely Targeted Metabolomics

Metabolites ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 46 ◽  
Author(s):  
Yajun Wang ◽  
Xiaojie Liang ◽  
Yuekun Li ◽  
Yunfang Fan ◽  
Yanlong Li ◽  
...  
Keyword(s):  
Soil Moisture ◽  
Light Intensity ◽  
Nutritional Quality ◽  
Climatic Factors ◽  
Northwest China ◽  
High Light Intensity ◽  
Climatic Conditions ◽  
Targeted Metabolomics ◽  
Lycium Barbarum ◽  
Widely Targeted Metabolomics

This study aimed at assessing the climatic factors influencing the wolfberry fruit morphology, and the composition of its nutritious metabolites. The cultivar Ningqi1, widely grown in Northwest China was collected from three typical ecological growing counties with contrasting climatic conditions: Ningxia Zhongning (NF), Xinjiang Jinghe (XF) and Qinghai Nomuhong (QF). During the ripening period, 45 fruits from different plantations at each location were sampled. A total of 393 metabolites were detected in all samples through the widely targeted metabolomics approach and grouped into 19 known classes. Fruits from QF were the biggest followed by those from XF and NF. The altitude, relative humidity and light intensity had negative and strong correlations with most of the metabolites, suggesting that growing wolfberry in very high altitudes and under high light intensity is detrimental for the fruit nutritional quality. Soil moisture content is highly and negatively correlated with vitamins, organic acids and carbohydrates while moderately and positively correlated with other classes of metabolites. In contrast, air and soil temperatures exhibited positive correlation with majority of the metabolites. Overall, our results suggest high soil and air temperatures, low altitude and light intensity and moderate soil moisture, as the suitable conditions to produce Lycium fruits with high content of nutritious metabolites.

scholarly journals Extensive Metabolic Profiles of Leaves and Stems from the Medicinal Plant Dendrobium officinale Kimura et Migo

Metabolites ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 215 ◽  
Author(s):  
Cao ◽  
Ji ◽  
Li ◽  
Lu ◽  
Tian ◽  
...  
Keyword(s):  
Genomic Research ◽  
Dendrobium Officinale ◽  
Metabolic Profiles ◽  
Asian Countries ◽  
Targeted Metabolomics ◽  
Medicinal Species ◽  
Metabolomic Data ◽  
Metabolite Profiles ◽  
Widely Targeted Metabolomics ◽  
Metabolic Data

Dendrobium officinale Kimura et Migo is a commercially and pharmacologically highly prized species widely used in Western Asian countries. In contrast to the extensive genomic and transcriptomic resources generated in this medicinal species, detailed metabolomic data are still missing. Herein, using the widely targeted metabolomics approach, we detect 649 diverse metabolites in leaf and stem samples of D. officinale. The majority of these metabolites were organic acids, amino acids and their derivatives, nucleotides and their derivatives, and flavones. Though both organs contain similar metabolites, the metabolite profiles were quantitatively different. Stems, the organs preferentially exploited for herbal medicine, contained larger concentrations of many more metabolites than leaves. However, leaves contained higher levels of polyphenols and lipids. Overall, this study reports extensive metabolic data from leaves and stems of D. officinale, providing useful information that supports ongoing genomic research and discovery of bioactive compounds.

Identification of key taste components in loquat using widely targeted metabolomics

2020 ◽  
Vol 323 ◽  
pp. 126822 ◽  
Author(s):  
Shicheng Zou ◽  
Jincheng Wu ◽  
Muhammad Qasim Shahid ◽  
Yehua He ◽  
Shunquan Lin ◽  
...  
Keyword(s):  
Targeted Metabolomics ◽  
Widely Targeted Metabolomics
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