scholarly journals Antibody affinity as a driver of signal generation in a paper-based immunoassay for Ebola virus surveillance

Author(s):  
Lara P. Murray ◽  
Ramesh Govindan ◽  
Andrea C. Mora ◽  
James B. Munro ◽  
Charles R. Mace
2016 ◽  
Vol 214 (suppl 3) ◽  
pp. S229-S233 ◽  
Author(s):  
Yohei Kurosaki ◽  
N'Faly Magassouba ◽  
Hadja Aïssatou Bah ◽  
Barré Soropogui ◽  
Amadou Doré ◽  
...  

Author(s):  
B. G. Uzman ◽  
M. M. Kasac ◽  
H. Saito ◽  
A. Krishan

In conjunction with the cultivation and transplantation of cells from human tumors by the Programs of Microbiology and Immunogenetics, virus surveillance by electron microscopy has been routinely employed. Of particular interest in this regard have been 3 cell lines cultured from lymph nodes or spleen of 2 patients with Hodgkin's disease and 1 patient with Letterer-Siwe's disease. Each of these cell lines when transplanted in Syrian hamster neonates conditioned with anti-lymphocyte serum grew as serially transplantable tumors; from such transplants of the 3 cell lines cell cultures were retrieved.Herpes type virus particles (Figs. 1, 2, 3) were found in the primary cultures of all three lines, in frozen thawed aliquots of same, and in cultures retrieved from their tumors growing by serial transplantation in hamsters. No virus was detected in sections of 25 of the serially transplanted tumors. However, in 10 such tumors there were repeated instances of tubular arrays in the cisternae of the endoplasmic reticulum (Fig. 4). On serologic examination the herpes virus was shown to be the Epstein-Barr virus.


2004 ◽  
Vol 171 (4S) ◽  
pp. 112-112
Author(s):  
Aaron Milbank ◽  
Mike Aleman ◽  
Kelley Harsch ◽  
Nick Detore ◽  
Eric A. Klein ◽  
...  

1983 ◽  
Vol 44 (C6) ◽  
pp. C6-27-C6-34 ◽  
Author(s):  
B. K. Bein ◽  
J. Pelzl

2020 ◽  
Vol 3 (1) ◽  
pp. 43-57 ◽  
Author(s):  
Russel J Reiter ◽  
Qiang Ma ◽  
Ramaswamy Sharma

This review summarizes published reports on the utility of melatonin as a treatment for virus-mediated diseases. Of special note are the data related to the role of melatonin in influencing Ebola virus disease. This infection and deadly condition has no effective treatment and the published works documenting the ability of melatonin to attenuate the severity of viral infections generally and Ebola infection specifically are considered. The capacity of melatonin to prevent one of the major complications of an Ebola infection, i.e., the hemorrhagic shock syndrome, which often contributes to the high mortality rate, is noteworthy. Considering the high safety profile of melatonin, the fact that it is easily produced, inexpensive and can be self-administered makes it an attractive potential treatment for Ebola virus pathology.  


2015 ◽  
Vol 74 (8) ◽  
pp. 695-707 ◽  
Author(s):  
V. V. Naumenko ◽  
V.F. Solodovnik ◽  
A. V. Totskiy ◽  
J. T. Astola

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